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| 1 | WONCA研究论文摘要汇编——慢性阻塞性肺疾病对亚太地区的影响:基于亚洲人群的EPIC调查显示文摘背景慢性阻塞性肺疾病(COPD)是一种慢性、进行性呼吸减弱的临床病症,主要临床表现为不完全可逆性气流受限。在亚太地区,关于COPD患病率的研究较多,但关于COPD影响的研究较少,本研究旨在对COPD的现患病率及其对亚太地区的影响进行综合阐述。方法 2012年2月1日—5月16日,在亚太地区的9个区域进行人群调查。共有112 300个家庭接受调查,从中抽取符合本研究纳入标准(≥40岁;确诊为COPD、慢性支气管炎或肺气肿,或伴有慢性支气管炎症状)的居民69 279例,其中确诊为COPD的居民为4 289例。采用结构式调查问卷,通过面对面采访或电话随访的形式收集居民的相关资料,最终纳入患者1 841例。结果估算COPD总患病率为6.2%,其中19.1%为重症。调查前的12个月内,近一半患者(46.0%)的病情加重,其中19.0%的患者因病情加重而入院治疗。关于COPD对工作的影响,23.0%的患者表示无法工作,42.0%的患者认为该病限制了工作或活动能力。20.0%服用处方药的患者不知晓自身服用药物的名称;44.0%的患者在调查前12个月内服用过常见口服皮质类固醇处方,而吸入器的使用率(25.0%)较低。仅有37.0%的患者进行了肺功能检查,但89.0%接受检测的患者不知晓检查结果。结论亚太地区的COPD患病率较高,因患病带来的社会经济负担较大。COPD管理能力提升空间较大,患者和医生的疾病相关教育有待加强。 | Lim1 S Chi-Leung Lam D M AR | 2015 | 中国全科医学2015，18，28： | 20 |
| 2 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017，16，6： | 8 |
| 3 | 地中海膳食干预研究中来自胆碱通路的血浆代谢物与心血管病风险的关系显示文摘血浆甜菜碱水平以及胆碱代谢水平与主要心血管病终点之间的联系仍不清楚。研究者评估了胆碱通路的代谢物与偶发心血管病风险以及地中海膳食干预的潜在调节效应之间的相关性。 | 黄洁 叶鹏 Guasch-Ferré M Hu FB Ruiz-Canela M Bulló M Toledo E Wang DD Corella D Gómez-Gracia E Fiol M Estruch R Lapetra J Fitó M Arós F Serra-Majem L Ros E Dennis C Liang L Clish CB Martínez-González MA Salas-Salvadó J | 2017 | 中华高血压杂志2017，25，12： | 2 |
| 4 | Functional anatomy of the human cochlear nerve and its role in microvascular decompressions for tinnitus显示文摘 | De Ridder D Ryu H MФfller AR | 2004 | Neurosurgery2004，54，： | 1 |
| 5 | An outbreak of acute eosinophilie myositis attributed to human Sarcoeystis parasitism显示文摘 | Arness M K Brown J D Dubey J P | 1999 | J Trop Med & Hyg1999，61，4： | 1 |
| 6 | p27kipl is required for PTEN-induced G1 growth arrest显示文摘 | Gottschalk AR Basila D Wong M | 2001 | Cancer Res2001，61，5： | 1 |
| 7 | Does quality of reports of randomised trials affect estimates of intervention efficacy reported in Meta-analyses显示文摘 | Moher D Pham B Jones A Cook DJ Jadad AR Moher M | 1998 | Lancet1998，352，： | 1 |
| 8 | Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1 显示文摘 | Ceradini D J Kulkarni AR Callaghan M J | 2004 | Nat Med2004，10，8： | 1 |
| 9 | High-intensity training improves plasma glucose and acid-base regulation during intermittent maximal exercise in type 1 diabetes显示文摘 | Harmer AR Chisholm D J McKenna M J | 2007 | Diabetes Care2007，30，5： | 1 |
| 10 | Intramedullary spinal cord tumors in neurofibromatosis显示文摘 | Lee M Rezai AR Freed D | 1996 | Neurosurgery1996，38，1： | 1 |
| 11 | Heat treatment for disinfestation of empty grain storage bins 显示文摘 | TILLEY D R CASADA M E AR TH- UR F H | 2007 | Journal of Stored Products Research2007，43，3： | 1 |
| 12 | Invariant U2 RNA sequences bordering the branchpointrecognition region are essential for interaction with yeast SF3a and SF3bsubunits显示文摘 | YAN D ARES M | 1996 | Molecular and Cellular Biology1996，16，3： | 1 |
| 13 | Randomized trial of tacrolimus versus cyclosporin microemulsion in renal transplantation显示文摘 | Trompeter R Filler G Webb NJ Watson AR Milford DV Tyden G Grenda R Janda J Hughes D Ehrich JH Klare B Zacchello G Bjorn Brekke I McGraw M Perner F Ghio L Balzar E Friman S Gusmano R Stolpe J | 2002 | Pediatr Nephrol2002，17，3： | 1 |
| 14 | A sensitive direct sequencing assay based on nested PCR for the detection of HBV polymerase and surface glycoprotein mutations显示文摘 | Vincenti D Solmone M Garbuglia AR | 2009 | J Virol Methods2009，159，1： | 1 |
| 15 | Insulin-like growth factor 1 in- hibits apoptosis using the phosphatidylinositol 3'-kinase and mitogen- activated protein kinase pathways显示文摘 | P6rrizas M Sahiel AR LeRoith D | 1997 | Joumal of Biological Chemistry1997，272，1： | 1 |
| 16 | Subclass typing of IgG paraproteins by immunofixation electrophoresis显示文摘 | Klouche M Bradwell AR Wilhelm D | 1995 | Clin Chem1995，41，10： | 1 |
| 17 | The hallucinogen N, N-dimethyltryptamine (DMT) is an endogenous sigraa-1 receptor regulator 显示文摘 | FontaniUa D Johannessen M Hajipour AR Cozzi NV Jackson MB Ruoho AE | 2009 | Sci- ence2009，323，5916： | 1 |
| 18 | RNA-Seq analysis of sulfur-deprived Chlamydomonas cells reveals aspects of acclimationcritical for cell survival显示文摘 | Gonzlez-Ballester D Casero D Cokus S Pellegrini M Merchant SS Grossman AR | 2010 | Plant Cell2010，22，6： | 1 |
| 19 | Type III protein secretion is associated with poor clinical outcomes in patients with ventilator-associated pneumonia caused by Pseudomonas aeruginosa 显示文摘 | Hauser AR Cobb E Bodi M Mariscal D Valles J Engel JN Rello J | 2002 | CritCare Med2002，30，3： | 1 |
| 20 | Identification of the dynamic properties of joints using frequency- response functions显示文摘 | Č elič D Boltež ar M | 2008 | Journal of Sound and Vibration2008，317，12： | 1 |
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