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| 1 | Midkine, a cytokine that inhibits HIV infection by binding to the cell surface expressed nucleolin显示文摘生长因素 midkine (MK ) 是由堵住 HIV 粒子的附件到容许的细胞在 autocrine 和 paracrine 举止在细胞文化禁止 HIV 感染的 cytokine。MK mRNA 系统地从健康施主在成年的外部血淋巴细胞被表示,当它的表示显著地变得时,但是短暂地增加了在之上在有由公众房产管理局或通过 CD28 抗原的约会的 T 淋巴细胞的 IL-2 或 IFN-gamma 和激活的淋巴细胞的 vitro 治疗。到房间的 MK 的绑定在高度和一个低亲密关系绑定地点明确地发生。这个低亲密关系绑定地点是房间表面表示了 nucleolin,它在 HIV 粒子的起始的附件的机制被含有到房间。因此,而它阻止 MK 的绑定到低亲密关系绑定地点, nucleolin 有约束力的 HB-19 假肽没在 MK 绑定上有效果到高亲密关系绑定地点,因此建议 MK 的低亲密关系受体是 cell-surface-expressed nucleolin。共焦的免疫荧光激光显微镜学在不同的点揭示了 MK 和 cell-surface-expressed nucleolin 的 colocalization。nucleolin 的各种各样的删除构造的使用然后显示极端 C 终端 nucleolin 结束,包含氨基酸主题 RGG 的重复,作为绑 MK 的领域。到表面 nucleolin 的 MK 的特定的绑定独立于 heparan 硫酸盐和 chondroitin 硫酸盐 proteoglycans。在到房间的绑定以后, MK 由 nucleolin 和类脂化合物椽子在看起来被含有的一个活跃过程进入房间。有势力和与它在由各种各样的生理的刺激的淋巴细胞的提高的表示一起的 MK 的不同 anti-HIV 行动,指出 MK 是能涉及 HIV 的 cytokine 致病。 | Ara G Hovanessian | 2006 | Cell Research2006，16，2： | 5 |
| 2 | Immunohistochemical study of the digestive tract of Oligosarcus hepsetus显示文摘AIM: To describe the histology of the digestive tract and to investigate the occurrence of endocrine cells in Oligosarcus hepsetus (O. hepsetus ). METHODS: The digestive tract (DT) of O. hepsetus was divided into esophagus, two stomach regions (glandular and non-glandular) and two intestinal regions (anterior and posterior). These specimens were processed by routine histological techniques and stained with hematoxylin-eosin, Gomori's trichrome, periodic acid Schiff (PAS) and Alcian blue (AB). An immunohistochemical method using avidin-biotin-peroxidase was employed.RESULTS: The esophagus is lined with a non-keratinized stratified squamous epithelium that is reactive to PAS and AB. The stomach has a mucosa lined with a simple columnar epithelium with mucus-secreting cells that are reactive only to PAS. The intestine has a simple columnar epithelium with a brush border and goblet cells that are reactive to PAS and AB. Somatostatin, serotonin and cholecystokinin immunoreactive cells were identified throughout the DT.CONCLUSION: This study revealed adaptations for the species' diet and showed that the distribution and relative frequency of immunoreactive cells are similar to those of other fish. | Danielle A Vieira-Lopes Nadja L Pinheiro Armando Sales Adriana Ventura Francisco G Araújo Iracema D Gomes Aparecida A Nascimento | 2013 | World Journal of Gastroenterology2013，19，12： | 2 |
| 3 | Wind velocity and sand transport on a barchan dune显示文摘 | G Sauermann J.S Andrade L.P Maia U.M.S Costa A.D Araújo H.J Herrmann | 2003 | Geomorphology2003，，3： | 2 |
| 4 | Regular participation in sports is associated with enhanced physical fitness and lower fat mass in prepubertal boys显示文摘 | Ara I Vicente-Rodriguez G Jimenez- Ramirez J | | 0，，04： | 1 |
| 5 | Olmesartan decreases IL-1βand TNF-αlevels;downregulates MMP-2,MMP-9,COX-2,and RANKL;and upregulates OPG in experimental periodontitis显示文摘 | Araújo AA Lopes de Souza G Souza TO | 2013 | Naunyn Schmiedebergs Arch Pharmacol2013，386，10： | 1 |
| 6 | Detoxification of the herbicide propanil by means of Fenton process and Ti O2-photocatalysis显示文摘 | O M G S Araa J González D O | 2014 | Journal of Photochemistry and Photobiology A2014，219，： | 1 |
| 7 | Recent aspects of vasculitis and future direction 显示文摘 | Aras G | 2011 | Intern Med2011，50，18： | 1 |
| 8 | An infinite analogue of rings with stable range one显示文摘 | ARA P PEDERSEN G K PERERA F | 2000 | J Algebra2000，230，： | 1 |
| 9 | Simple rigid plastic model for seismic tilting of rigid walls 显示文摘 | Siddharthan R Ara A Norris G M | 1989 | Journal of Structural Engineering ASCE1989，118，： | 1 |
| 10 | Repair of massive ventral hernias with the separation of parts technique: Reversal of the ' Loss of Domain' 显示文摘 | Hadad I Small W Ara G | 2009 | Am Surg2009，75，2： | 1 |
| 11 | Influence of an anti-an giogenic treatment on 9L gliosarcoma, oxygenation and re sponse to eytotoxic therapy显示文摘 | Teicher B A Holden S A Ara G | 1995 | Int J Cancer1995，61，5： | 1 |
| 12 | Managing Corporate Performance: Investigating the Relationship Between Corporate Social Responsibility and Financial Performance in Emerging Markets显示文摘 | Aras G Aybars A Kuthu O | 2010 | International Journal of Productivity and Performance Management2010，59，3： | 1 |
| 13 | Bio-Oss collagen in the buccal gap at immediate implants:a 6-month study in the dog显示文摘 | Araújo M G Linder E Lindhe J | 2011 | Clin Oral Implants Res2011，22，1： | 1 |
| 14 | Design of optical wide-band log-periodic nanoantennas using surface integral equation techniques 显示文摘 | SOL TABOADA J M ARA~O G | 2013 | Optics Communications2013，，8： | 1 |
| 15 | Synthesis and character- ization of waterborne and phosphorus - containing flame retardant polyurethane coatings显示文摘 | CELEBI F ARAS L GUNDUZ G | 2003 | Journal of Coatings Technology2003，75，944： | 1 |
| 16 | Serum chitotriosidase activity is increased in subjects with atherosclerosie disease显示文摘 | Marta A Ara C Alberto G | 2003 | Arterioscler Thromb Vasc Biol2003，23，9： | 1 |
| 17 | Potassium-modified Mg(NH2)2/2Li H system for hydrogen storage显示文摘 | Wang J H Liu T Wu G T Li W Liu Y F Moysés Araújo C Scheicher R H Blomqvist A Ahuja R Xiong Z T Yang P Gao M X Pan H G Chen P | 2009 | Angewandte Chemie International Edition2009，48，： | 1 |
| 18 | Clinical importance of anti2 thyroglobulin auto-antibodies in patients with diferentiated thy- roid carcinoma: comparison with 99 mTcMIBI scans显示文摘 | kucuk ON Aras G Kulak HA | 2006 | Nucl Med Commun2006，27，11： | 1 |
| 19 | Correlation of 18F-FDG PET/CT find-ings with histopathological results in differentiated thyroid cancer patients who have increased thyroglobulin or antithyroglobulin anti- body levels and negative 1311 whole-body scan results显示文摘 | Ozkan E Aras G Kucuk NO | 2013 | Clin Nu- cl Med2013，38，5： | 1 |
| 20 | Specific detection of enterovirus71 directly from clinical specimens using rea-1 time RT-PCR hybrid ization probeassay显示文摘 | Tan E L Chow T K Kum aras inghe G | 2006 | Molecular and Cellular Probes2006，20，： | 1 |
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