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| 1 | Osteosarcopenia in autoimmune cholestatic liver diseases:Causes,management,and challenges显示文摘Primary biliary cholangitis and primary sclerosing cholangitis(PSC)are the most common cholestatic liver diseases(CLD)in adults and are both characterized by an immune pathogenesis.While primary biliary cholangitis is a model autoimmune disease,with over 90%of patients presenting very specific autoantibodies against mitochondrial antigens,PSC is considered an immune mediated disease.Osteoporosis is the most common bone disease in CLD,resulting in frequent fractures and leading to significant morbidity.Further,sarcopenia is emerging as a frequent complication of chronic liver diseases with a significant prognostic impact and severe implications on the quality of life of patients.The mechanisms underlying osteoporosis and sarcopenia in CLD are still largely unknown and the association between these clinical conditions remains to be dissected.Although timely diagnosis,prevention,and management of osteosarcopenia are crucial to limit the consequences,there are no specific guidelines for management of osteoporosis and sarcopenia in patients with CLD.International guidelines recommend screening for bone disease at the time of diagnosis of CLD.However,the optimal monitoring strategies and treatments have not been defined yet and vary among centers.We herein aim to comprehensively outline the pathogenic mechanisms and clinical implications of osteosarcopenia in CLD,and to summarize expert recommendations for appropriate diagnostic and therapeutic approaches. | Nicola Pugliese Ivan Arcari Alessio Aghemo Andrea G Lania Ana Lleo Gherardo Mazziotti | 2022 | World Journal of Gastroenterology2022，28，14： | 2 |
| 2 | The librarian in clinical care显示文摘 | Arcari R Lamb G | 1977 | Hosp Med Staff1977，6，12： | 1 |
| 3 | Microtensile bond strength of a nanofilled composite resin to human dentin after nonvital tooth bleaching显示文摘 | Arcari GM Araajo E Baratieri LN | 2007 | J Adhes Dent2007，9，3： | 1 |
| 4 | The in vitro and in vivo effects of yerba mate (Ilex paraguariensis) extract on adipogenesis显示文摘 | Arcari D P Santos J C Gambero A et 01 | 2013 | Food Chem2013，141，2： | 1 |
| 5 | Influence of the duration of treatment using a 10% carbamide peroxide bleaching gel on dentin surface microhardness:An in situ study显示文摘 | Gilberto Mtiller Arcari Luiz Narciso Baratieri Hamilton Pires Maia | 2005 | Quintessence Int2005，36，： | 1 |
| 6 | PF-03814735, an orally bio- available small molecule aurora kinase inhibitor for cancer therapy 显示文摘 | Jani JP Arcari J Bernardo V | 2010 | Mol Cancer Ther2010，9，4： | 1 |
| 7 | Analy- sis of DNA damage induced by aflatoxin BI in dunkin-hart- ley guinea pigs显示文摘 | Miranda D D C Arcari D P Ladeira M S P | 2007 | Mycopathologia2007，163，： | 1 |
| 8 | Ultrastructure of absorbing peripheral lymphatic vessel (ALPA) in guinea pig peyer's patches显示文摘 | Azzali G Vitale M Arcari M L | 2002 | Microvascular Res2002，64，： | 1 |
| 9 | Influence of the duration of treatment using a 10% carbamide peroxide bleaching gel on dentin surface microhardness:An in situ study显示文摘 | Arcari GM Baratieri LN Maia HP | 2005 | Quintessence Int2005，36，1： | 1 |
| 10 | Antiobesity effects of yerba mat6 extract (Ilex paraguariensis) in high-fat diet-induced obese mice显示文摘 | Arcari DP Bartchewsky W dos Santos TW | 2009 | Obesity2009，17，12： | 1 |
| 11 | Membrane treatment of secondary textile effluents for direct reuse显示文摘 | ROZZI A ANTONELLI M ARCARI M | 1999 | Wat Sci Tech1999，40，45： | 1 |
| 12 | The librarian in clinical care 显示文摘 | ARCARI R LAMB G | 1977 | Hosp Med Staff1977，6，12： | 1 |
| 13 | C reactive protein and its determinants in healthy men and women from European regions at different risk of coronary disease : the IMMIDIET Project 显示文摘 | Arcari A Zito F Di Castelnuovo A | 2008 | J Thromb Haemost2008，6，3： | 1 |
| 14 | Cognitive im- pairment and EEG background activity in adults with Down's syndrome: a topographic study 显示文摘 | Velikova S Magnani G Arcari C | 2011 | Human Brain Mapping2011，32，5： | 1 |
| 15 | Influence of postplacement in the racture resistance of endodontically treated in-cisors veneered with direct composite 显示文摘 | Baratieri LN De Andrada MA Arcari GM | 2000 | J Prosthet Dent2000，84，2： | 1 |
| 16 | The complete sequence of a full length eDNA for human liver glyceratdehyde-3-phossphate dehydrogenase : evidence for muhiple mRNA species 显示文摘 | Arcari P Martinelli R Salvatore F | 1984 | Nucleic Accid Res1984，12，23： | 1 |
| 17 | Macrophage migration inhibitory factor in prostatic adenocarcinoma correlation with tumor grading and combination endocrine treatment-related changes显示文摘 | Del vecchio MT Tripodi SA Arcari F | 2000 | Prostate2000，45，1： | 1 |
| 18 | Influence of the duration of treatment using a10%carbamide peroxide bleaching gel on dentin surface microhardness:An in situ study显示文摘 | Arcari GM Baratieri LN Maia HP | 2005 | Quintessence Int2005，36，1： | 1 |
| 19 | Primary pancreatic lymphoma - A report of five cases 显示文摘 | Arcari A Anselmi E Bernuzzi P | 2005 | Haematologica2005，90，3： | 1 |
| 20 | Influence of the duration of treatment using a 10% carbamide peroxide bleaching gel on dentin surface microhardness:an in situ study显示文摘 | Arcari GM Baratieri LN Maia HP | 2005 | Quintessence Int2005，36，1： | 1 |
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