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| 1 | Efficacy and safety of tenofovir disoproxil fumarate in pregnancy for the prevention of vertical transmission of HBV infection显示文摘AIM:To evaluate the effects of tenofovir disoproxil fumarate(TDF)use during late pregnancy to reduce hepatitis B virus(HBV)transmission in highly viremic mothers.METHODS:This retrospective study included 45 pregnant patients with hepatitis B e antigen(+)chronic hepatitis B and HBV DNA levels>107copies/mL who received TDF 300 mg/d from week 18 to 27 of gestation(n=21).Untreated pregnant patients served as controls(n =24).All infants received 200 IU of hepatitis B immune globulin(HBIG)within 24 h postpartum and 20μg of recombinant HBV vaccine at 4,8,and 24 wk.Perinatal transmission rate was determined by hepatitis B surface antigen and HBV DNA results in infants at week 28.RESULTS:At week 28,none of the infants of TDFtreated mothers had immunoprophylaxis failure,whereas2(8.3%)of the infants of control mothers had immunoprophylaxis failure(P=0.022).There were no differences between the groups in terms of adverse events in mothers or congenital deformities,gestational age,height,or weight in infants.At postpartum week 28,significantly more TDF-treated mothers had levels of HBV DNA<250 copies/mL and normalized alanine aminotransferase compared with controls(62%vs none,P<0.001;82%vs 61%,P=0.012,respectively).CONCLUSION:TDF therapy during the second or third trimester reduced perinatal transmission rates of HBV and no adverse events were observed in mothers or infants. | Mustafa Kemal Celen Duygu Mert Müzeyyen Ay Tuba Dal Safak Kaya Necmettin Yildirim Serda Gulsun Tunga Barcin Sevgi Kalkanli Mehmet Sinan Dal Celal Ayaz | 2013 | World Journal of Gastroenterology2013，19，48： | 26 |
| 2 | Imaging cerebral microbleeds using susceptibility weighted imaging: one step toward detecting vascular dementia 显示文摘 | Ayaz M Boikov AS Haacke EM | 2010 | J Magn Reson Imaging2010，31，1： | 1 |
| 3 | A survey on routing techniques in underwater wireless sensor networks显示文摘 | Ayaz M Nubaig I Abdullah A | 2011 | Journal of Network and Computer Application2011，34，6： | 1 |
| 4 | Factors affecting wool quality and quantity in sheep 显示文摘 | Kham M J Abbas A Ayaz M | 2012 | African Journal of Biotechnology2012，11，13： | 1 |
| 5 | The effects of Saccharomyces 5oulardii on bac terial translocation in rats with obstructive jaundice显示文摘 | Geyik M F Aldemir M Hosoglu S Ayaz C Satilmis S Buyuk bayram H | 2006 | Ann R Coll Surg Engl2006，88，： | 1 |
| 6 | Effects of rosiglitazone with insulin combination therapy on oxidative stress and lipid profile in left ventricular muscles of diabetic rats显示文摘 | Kavak S Ayaz L Emre M | | 0，，： | 1 |
| 7 | Sodium selenite protects against diabetes-induced alteratlons in the antloxidant defense system of the liver显示文摘 | Ayaz M Celik H A Aydln H H | 2006 | Diabetes Metab Res Rev2006，22，4： | 1 |
| 8 | Establishing a base- line phase behavior in magnetic resonance imaging to deter- mine normal vs abnormal iron content in the brain显示文摘 | Haacke EM Ayaz M Manova ES | 2007 | Magn Reson Imaging2007，26，2： | 1 |
| 9 | The role of a vascular access surgeon in ventriculo-venous shunts in difficult hydrocephalus 显示文摘 | Ayaz Hossain M Frampton AE Choo M | 2010 | J Vasc Access2010，11，2： | 1 |
| 10 | A Survey on Routing Techniques in Underwater Wireless Sensor Networks显示文摘 | Ayaz M Baig I Abdullah A | 2011 | Journal of Network and Computer Applications2011，34，6： | 1 |
| 11 | Imaging cerebral microbleeds using susceptibility weighted imaging:one steptoward detecting vascular dementia显示文摘 | Ayaz M Boikov A S Haacke E M | 2010 | J Magn Reson Imaging2010，31，1： | 1 |
| 12 | Imaging cerebral microb- leeds using susceptibility-weighted imaging: one step toward de- tecting vascular dementia显示文摘 | Ayaz M Boikov AS Haacke EM | 2010 | Magn Reson Imaging2010，31，1： | 1 |
| 13 | Sodium selenite pro-tects against diabetes-induced alterations in the antioxidant de-fense system of the liver显示文摘 | Ayaz M Celik H A Aydin H H | 2006 | Diabetes Metab Res Rev2006，22，4： | 1 |
| 14 | Imaging cerebral microbleeds using susceptibility weighted imaging: one step toward detecting vascular dementia显示文摘 | Ayaz M Boikov AS Haacke EM | 2010 | J Magn Reson Imaging2010，31，： | 1 |
| 15 | Imaging cerebral microbleeds using susceptibility weighted imaging:one step toward detecting vascular dementia显示文摘 | Ayaz M Boikov AS Haacke EM | 2010 | J Magn Reson Imaging2010，31，1： | 1 |
| 16 | Synthesis and antibacterial activity of substituted flavones, 4-thioflavones and 4-iminoflavones 显示文摘 | Mughal E U Ayaz M Hussain Z | 2006 | Bioorg Med Cbem2006，14，14： | 1 |
| 17 | Effect of selenite treatment on ultrastructural changes in experimental diabetic rat bones 显示文摘 | Ozdemir S Ayaz M Can B | 2005 | Biol Trace Elem Res2005，107，： | 1 |
| 18 | Establishing a baselinephase behavior in magnetic resonance imaging to determine normalvs abnormal iron content in the brain显示文摘 | Haacke EM Ayaz M Manova ES | 2007 | Magn Reson Imaging2007，26，2： | 1 |
| 19 | Semiautomated detection of cerebral microbleeds in magnetic resonance images显示文摘 | Barnes SR Haacke EM Ayaz M | 2011 | Magn Reson Imaging2011，29，6： | 1 |
| 20 | Protective effect of selenium treatment on diabeticinduced myocardial structural alterations显示文摘 | Ayaz M Can B | 2002 | Bio Trace Elem Res2002，89，3： | 1 |
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