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| 1 | 内皮Notch信号的抑制阻碍脂肪酸转运并导致成年心脏的代谢和血管重塑显示文摘营养成分在被肌肉细胞代谢利用之前通过内皮细胞转运。然而,对于内皮运输过程的调节知之甚少。Notch信号传导是发育过程中代谢和血管生成的关键调控因子。在该研究中,Jabs等研究了成年小鼠内皮Notch信号的遗传和药理学调控如何影响内皮脂肪酸转运、心脏血管生成和心脏功能。 | 刘青 叶鹏 Jabs M Rose AJ Lehmann LH Taylor J Moll I Sijmonsma TP Herberich SE Sauer SW Poschet G Federico G Mogler C Weis EM Augustin HG Yan M Gretz N Schmid RM Adams RH Gr9ne HJ Hell R Okun JG Backs J Nawroth PP Herzig S Fischer A | 2018 | 中华高血压杂志2018，26，3： | 6 |
| 2 | Effect of organic acids on aluminum toxicity in subsoils显示文摘 | Hue N V Craddock G R Adams F | 1986 | Soil Science Society of America Journal1986，50，： | 1 |
| 3 | 显示文摘 | HERBST D SMITH D ADAMS N G | 1989 | J Chem Soc Fraday Trans1989，285，10： | 1 |
| 4 | 显示文摘 | SMITH D ADAMS N G | 1989 | J Chem Soc:Fraday Trans1989，285，10： | 1 |
| 5 | Microstrueture of dense thin sheets of γ-TiAl fabricated by hot isostatic pressing of tape-cast monotapes 显示文摘 | ADAMS A G RAHAMAN M N DUTTON R E | 2008 | Materials Science and Engineering2008，447，： | 1 |
| 6 | Mesenchymal precursor cells in the blood of normal individuals显示文摘 | Zvaifler N J Marinova-Mutafchieva L Adams G | 2002 | Arthritis Res2002，2，6： | 1 |
| 7 | Computational Social Science显示文摘 | Lazer D Pentland A Adamic L Aral S Barabasi A L Brewer D Christakis N Contractor N Fowler J Gutmann M Jebara T King G Macy M Roy D Van Alstyne M | | 0，，5915： | 1 |
| 8 | The dynamic properties of carbon-glass fiber sandwich laminated composites,Theoretical,experimental and economic consideration显示文摘 | Ni R G Lin D N Adams R D | 1984 | Composites1984，15，4： | 1 |
| 9 | A comparison of column-displacement and centrifuge methods for obtai- ning soil solutions 显示文摘 | Adams F Burmester G Hue N | 1980 | Soil Science Society of America Journal1980，44，： | 1 |
| 10 | Langmuir显示文摘 | Glaser N Adams D J B ker A Glaser N Adams D J Boker A Krausch G | 2006 | 22:5 2272006，22，： | 1 |
| 11 | Follicular waves and circulating gonadotrophins in l-month old prepubettal heifers显示文摘 | Adams G P Evans A C O Rawlings N C | 1994 | J Reprod Fertil1994，100，： | 1 |
| 12 | Effect of organic acids on aluminum toxicity in subsoil显示文摘 | HUE N V CRADDOCK G R ADAMS F | 1986 | Soil Sci Soc Am J1986，50，： | 1 |
| 13 | Effect of organic acids on aluminum toxicity in subsoils显示文摘 | Hue N V Craddock G R Adams F | 1986 | Soil Sci Soc Am J1986，50，： | 1 |
| 14 | Lengthening clinicalcrowns:a solution for specific periodontal,restorative,and estheticproblems显示文摘 | Wolffe G N Van der Weijden F A Adam J | 1994 | Quintessence Int1994，25，2： | 1 |
| 15 | Carbon,nitrogen and O2 fluxes associated with the cyanobacterium Nodularia spumigena in the Baltic Sea显示文摘 | Ploug H Adam B Musat N Kalvelage T Lavik G Wolf-Gladrow D Kuypers M M M | | 0，，09： | 1 |
| 16 | The fluorescent toolbox for assessing protein location and func- tion 显示文摘 | Giepmans B N G Adams S R Ellisman M H | 2006 | Science2006，312，5771： | 1 |
| 17 | Changes in human hepatic metabolism in steatosis and cirrhosis显示文摘AIM To understand the underlying metabolic changes in human liver disease we have applied nuclear magnetic resonance(NMR) metabolomics analysis to human liver tissue.METHODS We have carried out pilot study using 1H-NMR to derive metabolomic signatures from human liver from patients with steatosis, nonalcoholic steatohepatitis(NASH) or alcohol-related liver damage(ARLD) to identify species that can predict outcome and discriminate between alcohol and metabolic-induced liver injuries. RESULTS Changes in branched chain amino acid homeostasis, tricarboxylic acid cycle and purine biosynthesis intermediates along with betaine were associated with the development of cirrhosis in both ARLD and nonalcoholic fatty liver disease. Species such as propylene glycol and as yet unidentified moieties that allowed discrimination between NASH and ARLD samples were also detected using our approach.CONCLUSION Our high throughput, non-destructive technique for multiple analyte quantification in human liver specimens has potential for identification of biomarkers with prognostic and diagnostic significance. | Zoe Schofield Michelle AC Reed Philip N Newsome David H Adams Ulrich L Günther Patricia F Lalor | 2017 | World Journal of Gastroenterology2017，23，15： | 1 |
| 18 | Mesenchymal precursor cells in the blood of normal individuals显示文摘 | AIFLER N J MARINOVA-MUTAFCHIEVA L ADAMS G | 2000 | Arthritis Res2000，2，6： | 1 |
| 19 | Influence of manufacturing conditions on the bioavailability of magnesium in calcined magnesites measured in vivo and in vitro显示文摘 | Adam C L Hemingway R G Ritchie N S | 1996 | J Agric Sci1996，127，： | 1 |
| 20 | Effect of organic acids on alumlnium toxicity in subsoils显示文摘 | Hue N V Craddock G R Adams F | 1986 | Soil Sci Soc Am J1986，50，： | 1 |
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