|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 尿钠排泄、血压、心血管病与死亡率的关系:社区前瞻性流行病学队列研究显示文摘WHO建议人群钠摄人<2 g/d作为预防心血管病的措施之一,但这一目标在任何国家都没有实现。该建议主要基于短期血压试验的个体水平数据,没有来自随机试验或观察性研究的关于低钠摄入与降低心血管事件的数据。前瞻性城市农村流行病学研究目前正在21个国家进行。该文对其中18个国家的数据进行分析,其中包含了临床结果数据。 | Mente A O'Donnell M Rangarajan S McQueen M Dagenais G Wielgosz A Lear S Ah STL Wei L Diaz R Avezum A Lopez-Jaramillo P Lanas F Mony P Szuba A Iqbal R Yusuf R Mohammadifard N Khatib R Yusoff K Ismail N Gulec S Rosengren A Yusufali A Kruger L Tsolekile LP Chifamba J Dans A Alhabib KF Yeates K Teo K Yusuf S 刘莉 叶鹏 | 2018 | 中华高血压杂志2018，26，12： | 29 |
| 2 | 茶叶摄入与中国成年人高密度脂蛋白胆固醇浓度纵向变化的关系显示文摘茶叶摄入与高密度脂蛋白胆固醇(high-density lipoprotein cholesterol,HDL-C)浓度的年龄相关变化之间的关系仍不清楚。该研究目的是探索茶摄入量与HDL-C浓度纵向变化之间的关系。研究人员通过调查问卷评估基线(2006年)的茶叶消费量,并在2006、2008、2010和2012年测量了未患有心血管病或癌症. | 刘莉 叶鹏 Huang S Li J Wu Y Ranjbar S Xing A Zhao H Wang Y Shearer GC Bao L Lichtenstein AH Wu S Gao X | 2018 | 中华高血压杂志2018，26，8： | 5 |
| 3 | 重组脊髓灰质炎病毒用于治疗复发胶质母细胞瘤(英文)显示文摘Background The prognosis of patients with recurrent World Health Organization(WHO)grade IV malignant glioma is dismal,and there is currently no effective therapy.We conducted a dose-finding and toxicity study in this population of patients,evaluating convection-enhanced,intratumoral delivery of the recombinant nonpathogenic polio-rhinovirus chimera(PVSRIPO).PVSRIPO recognizes the poliovirus receptor CD155,which is widely expressed in neoplastic cells of solid tumors and in major components of the tumor microenvironment.Methods We enrolled consecutive adult patients who had recurrent supratentorial WHO grade IV malignant glioma,confirmed on histopathological testing,with measurable disease(contrast-enhancing tumor of≥1 cm and≤5.5 cm in the greatest dimension).The study evaluated seven doses,ranging between 107 and 1010 50%tissue-culture infectious doses(TCID50),first in a dose-escalation phase and then in a dose-expansion phase.Results From May 2012 through May 2017,a total of 61 patients were enrolled and received a dose of PVSRIPO.Dose level-1(5.0×107TCID50)was identified as the phase 2 dose.One dose-limiting toxic effect was observed;a patient in whom dose level 5(1010TCID50)was administered had a grade 4 intracranial hemorrhage immediately after the catheter was removed.To mitigate locoregional inflammation of the infused tumor with prolonged glucocorticoid use,dose level 5 was deescalated to reach the phase 2 dose.In the dose-expansion phase,19%of the patients had a PVSRIPO-related adverse event of grade 3 or higher.Overall survival among the patients who received PVSRIPO reached a plateau of 21%(95%confidence interval,11 to 33)at 24 months that was sustained at 36 months.Conclusions Intratumoral infusion of PVSRIPO in patients with recurrent WHO grade IV malignant glioma confirmed the absence of neurovirulent potential.The survival rate among patients who receivedPVSRIPO immunotherapy was higher at 24 and 36 months than the rate among historical controls. | Desjardins A Gromeier M Herndon JE 2nd Beaubier N Bolognesi DP Friedman AH Friedman HS McSherry F Muscat AM Nair S Peters KB Randazzo D Sampson JH Vlahovic G Harrison WT McLendon RE Ashley D Bigner DD | 2018 | 中华神经外科疾病研究杂志2018，17，4： | 2 |
| 4 | Differential action of angiotensin Ⅱ and activity of angiotensin - converting enzyme in human bypass grafts显示文摘 | Borland JA Chester AH Crabbe S | 1998 | J Thorac Cardiovasc Surg1998，116，2： | 2 |
| 5 | Origins of breast cancer subtypes and therapeutic implications 显示文摘 | Sims AH Howell A Howell S J Clarke R B | 2007 | Nature Clin Pract Oncol2007，4，12： | 1 |
| 6 | Potent mimicry of infibronectin-induced intracellular signaling in glioma cells by the homodimeric snake venom disintegrin contortrostatin显示文摘 | Schmitmeier S Markland FS Schonthal AH | 2005 | Neurosurgery2005，57，1： | 1 |
| 7 | Suppression by cathepsin L inhibitors of the invasion of amnion membranes by murine cancer cells 显示文摘 | Yagel S Warner AH Nellans HN | 1989 | Cancer Res1989，49，13： | 1 |
| 8 | Transcutaneous photodynamic therapy alters the development of an adoptively transferred form of murine experimental autoimmune encephalomyelitis显示文摘 | Chan AH Levy JG | 1996 | Photochem Photobiol1996，64，： | 1 |
| 9 | Brain-derived neurotrophic factor and the development of structural neuronal connectivity 显示文摘 | Cohen-Cory S Kidane AH Shirkey N J | 2010 | Dev Neurobiol2010，70，5： | 1 |
| 10 | Influenza virus overcomes apoptosis by rapid multiplication显示文摘 | Kurokawa M Koyama AH Yasuoka S | 1999 | Int J Mol Med1999，3，： | 1 |
| 11 | Prevention of pleural effusion after hepatectomy using fibrinsealant 显示文摘 | Uetsuji S Komada Y Kwon AH | 1994 | Int Surg1994，79，2： | 1 |
| 12 | Antenatal inflammation induced TGF-betal but suppressed CTGF in preterm lungs 显示文摘 | Kunzmann S Speer CP Jobe AH | 2007 | Am J Physiol Lung Cell Mol Physiol2007，292，1： | 1 |
| 13 | Evaluation of RANKL/OPG serum concentration ratio as a new biomarker for coronary artery calcification : a pilot study 显示文摘 | Mohammadpour AH Shamsara J Nazemi S | 2012 | Thrombosis2012，2012，30： | 1 |
| 14 | Polymorphism in the STAT6 gene encodes risk for nut allergy 显示文摘 | Amoli MM Hand S Hajeer AH | 2002 | Genes Immun2002，3，： | 1 |
| 15 | Explaining development and change in organizations 显示文摘 | Van de Ven AH Poole M S | 1995 | Academy of Management Review1995，20，3： | 1 |
| 16 | AC133, a novel marker for human hematopoietic stem and progenitor cells 显示文摘 | Yin AH Miraglia S Zanjani ED | 1997 | Blood1997，90，： | 1 |
| 17 | Two-photon-excited fluorescence imaging of human RPE cells with a femtosecond Ti: Sapphire laser显示文摘 | Bindewald-Wittich A Han M Schmitz-Valckenberg S Snyder Sar- ah R Giese G Bille Josef F | 2006 | Invest Ophthalmol Vis Sci2006，47，10： | 1 |
| 18 | Resistance to intravenous immunoglobulin in children with Kawasaki disease显示文摘 | Tremoulet AH Best BM Song S | | 0，，01： | 1 |
| 19 | Molecular genetic evidence that endometriosis is a precursor of ovarian cancer显示文摘 | Prowse AH Manek S Varma R | 2006 | Int J Cancer2006，119，3： | 1 |
| 20 | Compara- tive study of hamstring and quadriceps strengthening treatments in the management of knee osteoarthritis显示文摘 | A1-Johani AH Kachanathu S J Ramadan Hafez A | 2014 | J Phys Ther Sei2014，26，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员