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| 1 | Outcome in obscure gastrointestinal bleeding after capsule endoscopy显示文摘AIM: To investigate the clinical impact of capsule endoscopy(CE) after an obscure gastrointestinal bleeding(OGIB) episode, focusing on diagnostic work-up, followup and predictive factors of rebleeding. METHODS: Patients who were referred to Hospital del Mar(Barcelona, Spain) between 2007 and 2009 for OGIB who underwent a CE were retrospectively analyzed. Demographic data, current treatment with non-steroid antiinflammtory drugs or anticoagulant drugs, hemoglobin levels, transfusion requirements, previous diagnostic tests for the bleeding episode, as well as CE findings(significant or non-significant), work-up and patient out-comes were analyzed from electronic charts. Variables were compared by χ 2 analysis and Student t test. Risk factors of rebleeding were assessed by Log-rank test, Kaplan-Meier curves and Cox regression model. RESULTS: There were 105 patients [45.7% women, median age of 72 years old(interquartile range 56-79)] and a median follow-up of 326 d(interquartile range 123-641) included in this study. The overall diagnostic yield of CE was 58.1%(55.2% and 63.2%, for patients with occult OGIB and overt OGIB, respectively). In 73 patients(69.5%), OGIB was resolved. Multivariate analysis showed that hemoglobin levels lower than 8 g/dL at diagnosis [hazard ratios(HR) = 2.7, 95%CI: 1.9-6.3], patients aged 70 years and above(HR = 2.1, 95%CI: 1.2-6.1) and significant findings in CE(HR = 2.4, 95%CI: 1.1-5.8) were independent predictors of rebleeding. CONCLUSION: One third of the patients presented with rebleeding after CE; risk factors were hemoglobin levels < 8 g/dL, age ≥ 70 years or the presence of significant lesions. | Alex Caas-Ventura Lucia Márque Xavier Bessa Josep Maria DedeuDepartment of Gastroenterology Hospital del Mar Research Institute Pompeu Fabra University Marc Puigvehí Sílvia Delgado-Aros Ines Ana Ibáez Agustin Seoane Luis Barranco Felipe Bory Montserrat Andreu Begoa González-Suárez | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，11： | 4 |
| 2 | Mapping aboveground biomass and its prediction uncertainty using LiDAR and field data, accounting for tree-level allometric and LiDAR model errors显示文摘Background: The increasing availability of remotely sensed data has recently challenged the traditional way of performing forest inventories, and induced an interest in model-based inference. Like traditional design-based inference, model-based inference allows for regional estimates of totals and means, but in addition for wall-to-wall mapping of forest characteristics. Recently Light Detection and Ranging(LiDAR)-based maps of forest attributes have been developed in many countries and been well received by users due to their accurate spatial representation of forest resources. However, the correspondence between such mapping and model-based inference is seldom appreciated. In this study we applied hierarchical model-based inference to produce aboveground biomass maps as well as maps of the corresponding prediction uncertainties with the same spatial resolution. Further, an estimator of mean biomass at regional level, and its uncertainty, was developed to demonstrate how mapping and regional level assessment can be combined within the framework of model-based inference.Results: Through a new version of hierarchical model-based estimation, allowing models to be nonlinear, we accounted for uncertainties in both the individual tree-level biomass models and the models linking plot level biomass predictions with LiDAR metrics. In a 5005 km2 large study area in south-central Sweden the predicted aboveground biomass at the level of 18 m×18 m map units was found to range between 9 and 447 Mg·ha^-1. The corresponding root mean square errors ranged between 10 and 162 Mg·ha^-1. For the entire study region, the mean aboveground biomass was 55 Mg·ha^-1 and the corresponding relative root mean square error 8%. At this level 75%of the mean square error was due to the uncertainty associated with tree-level models.Conclusions: Through the proposed method it is possible to link mapping and estimation within the framework of model-based inference. Uncertainties in both tree-level biomass models and models linking plot level biomass with LiDAR data are accounted for, both for the uncertainty maps and the overall estimates. The development of hierarchical model-based inference to handle nonlinear models was an important prerequisite for the study. | Svetlana Saarela AndréWästlund Emma Holmström Alex Appiah Mensah Sören Holm Mats Nilsson Jonas Fridman Göran Ståhl | 2020 | Forest Ecosystems2020，7，3： | 3 |
| 3 | Imaging pancreatobiliary ductal system with optical coherence tomography: A review显示文摘An accurate, noninvasive and cost-effective method of in situ tissue evaluation during endoscopy would be highly advantageous for the detection of dysplasia or early cancer and for identifying different disease stages. Optical coherence tomography(OCT) is a noninvasive, high-resolution(1-10 μm) emerging optical imaging method with potential for identifying microscopic subsurface features in the pancreatic and biliary ductal system. Tissue microstructure of pancreaticobiliary ductal system has been successfully imaged by inserting an OCT probe through a standard endoscope operative channel. High-resolution OCT images and the technique's endoscopic compatibility have allowed for the microstructural diagnostic of thepancreatobiliary diseases. In this review, we discussed currently available pancreaticobiliary ductal imaging systems to assess the pancreatobiliary tissue microstructure and to evaluate varieties of pancreaticobiliary disorders and diseases. Results show that OCT can improve the quality of images of pancreatobiliary system during endoscopic retrograde cholangiopancheatography procedure, which may be important in distinguishing between the neoplastic and non-neoplastic lesions. | Mohammad S Mahmud Gray R May Mohammad M Kamal Ahmed S Khwaja Carry Sun Alex Vitkin Victor XD Yang | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，11： | 2 |
| 4 | To Look or Book-An Examination of Consumers' Apprehensivene toward Internet Use显示文摘 | Alex M Sukind Mark A Bonn Chekitan S Dev | 2003 | Journal of Travel Research2003，42，3： | 1 |
| 5 | 0-Defensins: cyclic pep- tides with endless potential显示文摘 | Robert I L Alex M C Michael E S | 2012 | J Biol Chem2012，287，27： | 1 |
| 6 | A 30-year expe rience in the management of primary carcinoma of vagi ha:analysis of prognostic factors and treatment modali ties显示文摘 | Richard G Stock M D Alex S J | 1995 | Gynecol Oncol1995，56，1： | 1 |
| 7 | Effects of yttrium on the sintering and microstructure of alumina-silicon carbide 'nanocomposites' 显示文摘 | ALEX M C IAN P S RICHARD I T STEVE G R | 2005 | J Am Ceram Soc2005，88，9： | 1 |
| 8 | Star pattern identification using discrete attitude variation technique显示文摘 | Rao G N Bhat M S Alex T K | 2005 | Journal of Guidance Control and Dynamics2005，28，6： | 1 |
| 9 | Characterization of polyploid wheat genomic diversity using a high-density 90 000 single nucleotide polymorphism array 显示文摘 | Wang SC Debbie W Kerrie F Alexandra A Shiaoman C Bevan EH Marco M Silvio S Sara GM Luigi C Anna MM Alex W Stuart S Gary B Ralf W Joerg P International Wheat Genome Sequencing Consortium Morten L Diane M Rudi A Rudy D Gina BG Abraham K Alina RA Catherine F Jerome S Michele M Curtis P Luo MC Jan DMM Jorge D Martin G Roberto T Cindy L Ivan M Colin C Keith JE Matthew H Eduard A | 2014 | Plant Biotechnol J2014，12，： | 1 |
| 10 | Virtual auditing agents: the EDGAR agent challenge 显示文摘 | Kay M N Alex K Rajendra P S Vasarhelyi Miklos A | 2000 | Decision Support System2000，28，： | 1 |
| 11 | Electrolyte composition for Cu electrochemical mechanical planarization 显示文摘 | ABHINAV T CRAIG B IAN I S LI Y Z FRANCOIS D ALEX B JAMES M A | 2008 | Journal of The Electrochemical Society2008，155，7： | 1 |
| 12 | Numerical Study on Effects of Coal Properties on Spontaneous Heating in Longwall Goaf Areas 显示文摘 | Li M Y Alex C S | 2008 | Fuel2008，87，15： | 1 |
| 13 | The involvement of cysteine proteases and pretease inhibitor genes in the regulation of programmed cell death in plants显示文摘 | MAZAL S Beatrice B Massimo D Ester M Alex L | | 0，，： | 1 |
| 14 | Screen-printable silver pastes with metallic nano-zinc and nano-zinc alloys for crystalline silicon photovoltaic cells显示文摘 | Alex S Ionkin Brian M Fish Zhigang Rick Li | 2011 | Appl Mater Interf2011，3，： | 1 |
| 15 | I-kB and p65 regulate the cytoplasmic shuttling of nuclear corepressors:Cross-talk between notch and NF-kB pathways 显示文摘 | Llui's E Julia I E Alex R M | 2003 | Mol Biol Cell2003，14，： | 1 |
| 16 | Cross-species amplification of microsatellite loci in aphids: assessment and application 显示文摘 | ALEX C C W BLANDINE M JEAN-CHRISTOPHE S | 2004 | Molecular Ecology Notes2004，4，： | 1 |
| 17 | Genetic variation in IL28B and spontaneous clearance of hepatitis C virus显示文摘 | Thomas D L Thio C L Martin M P Qi Y Ge D O'Huigin C Kidd J Kidd K Khakoo S I Alex | | 0，，7265： | 1 |
| 18 | Complete genome sequence and taxonomic position of Anguillid herpesvirus 显示文摘 | VAN BEURDEN S J ALEX BOSSERS VOORBERGEN- LAARMAN M H A et ai | 2010 | J Gen Virol2010，91，4： | 1 |
| 19 | Star pattern identification using discrete attitude variation technique 显示文摘 | Rao G N Bhat M S Alex T K | 2005 | Journal of Guieanee Contral and Dynamics2005，28，6： | 1 |
| 20 | Ferroelectrie nanotubes显示文摘 | Morrison F D Luo Y Szafraniak I Nagarajan V Wehrspoh R B Steinhart M Wendorff J H Zakharov N D Mishina E D Vorotilov K A Sigov A S Nakabayshi S Alexe M Ramesh R Scott J F | 2003 | Rev Adv Mater Sci2003，4，： | 1 |
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