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| 1 | Fondaparinux预防老年急性内科患者发生静脉血栓形成的效果与安全性:随机安慰剂对照研究显示文摘目的:观察 Fondaparinux 对具有中高度静脉血栓发生危险的老年急性内科住院患者的抗凝效果与安全性。设计:双盲随机安慰剂对照研究。背景:8个国家的35个中心。参与者:849例≥60岁内科患者,住院原因分别为充血性心力衰竭、慢性肺病合并急性呼吸系统疾患、急性炎症性或感染性疾病,预期至少住院4天以上。干预:2.5 mg Fondaparinux 或安慰剂,每天1次皮下注射,持续6~14天。观察指标:主要指标为静脉血栓形成(治疗后15天内采用双侧静脉造影检查)及有症状的静脉血栓;次要指标为死亡与出血。患者随访时间为1个月。结果:Fondaparinux 治疗组425例患者和安慰剂组414例患者接受了安全性分析(10例未治疗)。644例患者(75.9%)可接受主要指标分析。静脉血栓检出率在 Fondaparinux 治疗组为5.6%(18/321),安慰剂组为10.5%(34/323),相对危险减少46.7%(95% CI 7.7%~69.3%)。安慰剂组5例患者发生有症状的静脉血栓,Fondaparinux治疗组无患者发生有症状的静脉血栓(P=0.029)。两组均有1例(0.2%)患者发生严重出血。随访结束时,安慰剂组、Fondaparinux 治疗组分别死亡25(6.0%)、14(3.3%)例患者。结论:Fondaparinux 可有效预防急性内科老年患者无症状性及有症状的静脉血栓。严重出血几率两组相似。 | Alexander T Cohen Bruce L Davidson Alexander S Gallus Michael R Lassen Martin H Prins Witold Tomkowski Alexander G G Turpie Jan F M Egberts Anthonie W A Lensing 石汉平(译) 王深明(校) | 2006 | 英国医学杂志中文版2006，9，5： | 3 |
| 2 | Nitrogen and Carbon Isotope Data of Olenekian to Anisian Deposits from Kamenushka/South Primorye, Far-Eastern Russia and Their Palaeoenvironmental Significance显示文摘The Kamenushka Formation, exposed in the northern part of South Primorye(Kamenushka-1 and Kamenushka-2 sections), is one of the few localities in the world with richly fossiliferous Lower–Upper Olenekian sedimentary successions. Lower to Middle Triassic ammonoid-, brachiopod-and conodont-bearing silty-clayey deposits of the Kamenushka-1 and Kamenushka-2 sections have been isotope-geochemically investigated in detail. As a result, these sections, together with the previously investigated Abrek Section, exposed in the southern part of South Primorye, provide almost complete 15 Norg-and 13 Corg-records for the Lower Triassic of this region. Nine Nisotope intervals and the five negative C-isotope excursions, reflecting, apparently, unstable climatic and hydrological conditions, have been distinguished in the Lower Triassic of South Primorye. On the basis of the new C-isotope data the Mesohedenstroemia bosphorensis Zone(upper part), Shimanskyites shimanskyi and Neocolumbites insignis zones of South Primorye are correlated now with the Lower Smithian part of the Yinkeng Formation, the Upper Smithian part of the Helongshan Formation and the Middle Spathian part of the Nanlinghu Formation in South China, respectively, as has been observed in the Abrek, Kamenushka-2, West Pingdingshan and Majiashan sections. | Yuri D Zakharov Micha Horacek Alexander M Popov Liana G Bondarenko | 2018 | Journal of Earth Science2018，29，4： | 2 |
| 3 | 脊髓损伤后残存自主神经功能载录国际标准显示文摘近年来,脊髓损伤神经学分类园际标准(International Stand- ards for the Neurological Classification of Spinal Cord Injury, ISNCSCI)被用来记载脊髓损伤后运动和感觉功能的损害,目前该标准已是第六版。1992年第一份国际认可的标准出版时,曾进行了较大的修订,修订内容包括完全性损伤与不完全性损伤的定义, | MS Alexander AB Jackson W Donovan DE Graves SL Elliott A Krassioukov AW Sheel I Estoresl B Green A Gousse NL Braekett D Cardenas M Kennelly A-K Karlason F Biering-Sorensen K Krogh T Linsenmeyer R Marino J Ditunno CJ Mathias I Perkash G Creasey G Schilero J Wecht B Schurch V Dietz J Sonksen S Stiens D Bodner LA Wuermser J-J Wyndaele 周谋望 刘楠 S Charlifue | 2010 | 中华物理医学与康复杂志2010，32，4： | 2 |
| 4 | Agerelated cortical grey matter reductions in nondemented Down's syndrome adults determined by MRI with voxelbased morphometry显示文摘 | Teipel S J Alexander G E Schapiro M B | 2004 | Brain2004，127，4： | 1 |
| 5 | Dynamic light scattering tech -niques and their applications in food science 显示文摘 | Alexander M Dalgleish D G | 2006 | Food Biophysics2006，，1： | 1 |
| 6 | Application of transmission diffusing wave spectroscopy to the study of gelation of milk by acidification and rennet 显示文摘 | Alexander M Dalgleish D G | 2004 | Colloids and Surfaces B: Biointerfaces2004，38，： | 1 |
| 7 | Advanced ray tracing with earth atmospheric models 显示文摘 | Kunz G J Moerman M M Eijk van Alexander M J | 2002 | SPIE2002，4718，： | 1 |
| 8 | Human parathyroid hormone 1-34 reverses bone loss in ovariectomized mice显示文摘 | Alexander JM Bab I Fish S Muller R Uchiyama T Gronowicz G Nahounou M Zhao Q White DW Chorev M Gazit D Rosenblatt M | | 0，，： | 1 |
| 9 | The role of red and processed meat in colorectal cancer development:a perspective显示文摘 | OOSTINDJER M ALEXANDER J AMDAM G V | 2014 | Meat Science2014，97，4： | 1 |
| 10 | Steel Corrosion on RC Structures under Sustained Service Loads A Critical Review显示文摘 | Malumbela G Alexander M Moyo P | 2009 | Engineering Structures2009，31，11： | 1 |
| 11 | Mean-variance portfolio selection with ' at-risk 'constraints and discrete distributions 显示文摘 | Alexander G J Baptista A M Yan S | 2007 | Journal of Banking Finance2007，31，12： | 1 |
| 12 | Lateral Deform- ation of RC Beams under Simultaneous Load and Steel Corrosion 显示文摘 | Malumbela G Alexander M Moyo P | 2010 | Construction and Building Materials2010，24，1： | 1 |
| 13 | Acid gelation in heated and unheated milks: inter acttions between serum protein complexes and the surfaces of casein micelles 显示文摘 | Donato L Alexander M Dalgleish D G | 2007 | Journal of Agricultural and Food Chemistry2007，55，： | 1 |
| 14 | Coumarins from two Coleonema species 显示文摘 | Alexander I G Viaran J M Noreen B O | 1987 | Phytochemistry1987，26，： | 1 |
| 15 | Inversion control in sugarcane juice with sodium Metasilieate显示文摘 | Alexander G B Acin N D Zapata R M | 1971 | Proc Int Soc Sugarcane Technol1971，13，： | 1 |
| 16 | Effect of controlled environmental conditions on durability index parameters of portland cement concretes 显示文摘 | Griesel E J Alexander M G | 2001 | Cement Concrete and Aggregates2001，23，1： | 1 |
| 17 | Variation of Steel Loss and Its Effect on the Ultimate Flexural Ca- pacity of RC Beams Corroded and Repaired under Load 显示文摘 | Malumbela G Alexander M Moyo P | 2010 | Construction and Building Materials2010，24，6： | 1 |
| 18 | Manufacturing Technology 显示文摘 | Alexander J M Brewer R C Rowe G W | 1999 | Tribology Transactions1999，59，2： | 1 |
| 19 | Nonextraction orthodontic therapy:posttreatment dental and skeletal stability 显示文摘 | GLENN G SINCLAIR P M ALEXANDER R G | 1987 | Am J orthod dentofacial orthop1987，92，： | 1 |
| 20 | Reacttions in supererifical fluid: a case study of the thermo-dynamie solvent effects on a Diels-Alder reaction in supercritical CO2显示文摘 | Paulaitis M E Alexander G C | 1987 | Pure and Applied Chemistry1987，59，1： | 1 |
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