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| 1 | Near-infrared fluorescence imaging of a solitary fibrous tumor of the pancreas using methylene blue显示文摘A 67-year-old female presented with unexplained abdominal pain. A contrast-enhanced computed tomography scan of the abdomen incidentally revealed a mass in the uncinate process of the pancreas. This mass was resected and based on histopathological findings, diagnosed as a solitary fibrous tumor (SFT) of the pancreas. A SFT is an extremely rare benign mesenchymal tumor that in 65% of cases affects the visceral pleura but can also affect extra-pleural sites. The intraoperative demarcation of pancreatic tumors, such as SFTs, can bechallenging. In this report, the first clear intraoperative identification of a SFT of the pancreas in a human was shown using near-infrared fluorescence and methylene blue. | Joost R van der Vorst Alexander L Vahrmeijer Merlijn Hutteman Tjalling Bosse Vincent THBM Smit Cornelis JH van de Velde John V Frangioni Bert A Bonsing | 2012 | World Journal of Gastrointestinal Surgery2012，4，7： | 7 |
| 2 | Colonoscopy quality with Entonox? vs intravenous conscious sedation:18608 colonoscopy retrospective study显示文摘AIM To compare colonoscopy quality with nitrous oxide gas(Entonox?) against intravenous conscious sedation using midazolam plus opioid.METHODS A retrospective analysis was performed on a prospectively held database of 18608 colonoscopies carried out in Lothian health board hospitals between July 2013 and January 2016.The quality of colonoscopies performed with Entonox was compared to intravenous conscious sedation(abbreviated in this article as IVM).Furthermore,the quality of colonoscopies performed with an unmedicated group was compared to IVM.The study used the following key markers of colonoscopy quality:(1) patient comfort scores;(2) caecal intubation rates(CIRs); and (3) polyp detection rates (PDRs).We used binary logistic regression to model the data.RESULTS There was no difference in the rate of moderate-toextreme discomfort between the Entonox and IVM groups (17.9% vs 18.8%; OR = 1.06,95%CI: 0.95-1.18,P = 0.27).Patients in the unmedicated group were less likely to experience moderate-to-extreme discomfort than those in the IVM group(11.4% vs 18.8%; OR = 0.71,95%CI: 0.60-0.83,P < 0.001).There was no difference in caecal intubation between the Entonox and IVM groups(94.4% vs 93.7%; OR = 1.08,95%CI: 0.92-1.28,P = 0.34).There was no difference in caecal intubation between the unmedicated and IVM groups (94.2% vs 93.7%; OR = 0.98,95%CI: 0.79-1.22,P = 0.87).Polyp detection in the Entonox group was not different from IVM group (35.0% vs 33.1%; OR = 1.01,95%CI: 0.93-1.10,P = 0.79).Polyp detection in the unmedicated group was not significantly different from the IVM group (37.4% vs 33.1%; OR = 0.97,95%CI: 0.87-1.08,P = 0.60).CONCLUSION The use of Entonox was not associated with lower colonoscopy quality when compared to intravenous conscious sedation using midazolam plus opioid. | Alexander R Robertson Nicholas A Kennedy James A Robertson Nicholas I Church Colin L Noble | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，9： | 3 |
| 3 | Fondaparinux预防老年急性内科患者发生静脉血栓形成的效果与安全性:随机安慰剂对照研究显示文摘目的:观察 Fondaparinux 对具有中高度静脉血栓发生危险的老年急性内科住院患者的抗凝效果与安全性。设计:双盲随机安慰剂对照研究。背景:8个国家的35个中心。参与者:849例≥60岁内科患者,住院原因分别为充血性心力衰竭、慢性肺病合并急性呼吸系统疾患、急性炎症性或感染性疾病,预期至少住院4天以上。干预:2.5 mg Fondaparinux 或安慰剂,每天1次皮下注射,持续6~14天。观察指标:主要指标为静脉血栓形成(治疗后15天内采用双侧静脉造影检查)及有症状的静脉血栓;次要指标为死亡与出血。患者随访时间为1个月。结果:Fondaparinux 治疗组425例患者和安慰剂组414例患者接受了安全性分析(10例未治疗)。644例患者(75.9%)可接受主要指标分析。静脉血栓检出率在 Fondaparinux 治疗组为5.6%(18/321),安慰剂组为10.5%(34/323),相对危险减少46.7%(95% CI 7.7%~69.3%)。安慰剂组5例患者发生有症状的静脉血栓,Fondaparinux治疗组无患者发生有症状的静脉血栓(P=0.029)。两组均有1例(0.2%)患者发生严重出血。随访结束时,安慰剂组、Fondaparinux 治疗组分别死亡25(6.0%)、14(3.3%)例患者。结论:Fondaparinux 可有效预防急性内科老年患者无症状性及有症状的静脉血栓。严重出血几率两组相似。 | Alexander T Cohen Bruce L Davidson Alexander S Gallus Michael R Lassen Martin H Prins Witold Tomkowski Alexander G G Turpie Jan F M Egberts Anthonie W A Lensing 石汉平(译) 王深明(校) | 2006 | 英国医学杂志中文版2006，9，5： | 3 |
| 4 | Delayed,spontaneous hypothermia reduces neuronal damage after asphyxial cardiac arrest in rats显示文摘 | Hickey R W Ferimer H Alexander H L | 2000 | Crit Care Med2000，28，： | 1 |
| 5 | Bacterial trans location:a potential sourc efor infection in acute pancreatitis显示文摘 | Gianotti L Munda R Alexander JW | 1993 | Pancreas1993，8，4： | 1 |
| 6 | Clinical rating sys- tems for the ankle-hindfoot,midfoot,hallux,and lesser toes显示文摘 | Kitaoka H B Alexander L J Adelaar R S | 1994 | Foot Ankle Int1994，15，7： | 1 |
| 7 | Synthesis of a-hydroxyphosphonates phosphonates using a solid supported base 显示文摘 | Alexander C W Albiniak P A Gibson L R | 2000 | Phosphorus Sulfur and Silicon ( S1042-6507 )2000，167，： | 1 |
| 8 | Effect of an extract from sulla (Hedysarum coronarium) containing condensed tannins on the migration of three sheep gastrointestinal nematodes in vitro显示文摘 | MOLAN A L ALEXANDER R A BROOKES I M | 2000 | Proceedings of the New Zealand Society of Animal Production2000，60，： | 1 |
| 9 | Formation and reactions of alkyl adamantanes in sediments:carbon surface reactions显示文摘 | Berwick L Alexander R Pierce K | 2011 | Organic Geochemistry2011，42，7： | 1 |
| 10 | Tetracyclic diterpenoid hydrocarbons in some Australian coals, sediments and crude oils显示文摘 | Noble R A Alexander R Kagi R l | 1985 | Geochimica et Cosmochimica Acta1985，49，10： | 1 |
| 11 | Antiangiogenic gene therapy of cancer utilizing a recombinant adenovirus to elevate systemic endostatin levels in mice显示文摘 | Feldman A L Restifo N P Alexander H R | 2000 | Cancer Res2000，，60： | 1 |
| 12 | Sexual arousal and organs in women:effect of spinal cord injury显示文摘 | Sipski M L Alexander C J Rosen R | 2001 | Ann Neurol2001，49，1： | 1 |
| 13 | Thyroid nodule guide- lines:agreement,disagreement and need for future research显示文摘 | Paschke R Hegedtis L Alexander E | 2011 | Nat Rev Endocrinol2011，7，6： | 1 |
| 14 | Coordinate gene activity in response to agents that in- duce systemic acquired resistance显示文摘 | WARD E R UKNESS S J WILLIAMS S C DINCHER S S WIEDER- HOLD D L ALEXANDER D C AHL-GOY P METRAUX J P RYALS J A | 1991 | Plant Cell1991，3，10： | 1 |
| 15 | Single carbon surface reaction of 1-octadecene and 2,3,6-trimethylphenol on activated carbon:implications for methane formation in sediments显示文摘 | Alexander R Berwick L Pierce K | 2011 | Organic Geochemistry2011，42，5： | 1 |
| 16 | Improvements in 230Th dating, 230Th and 254U half-life values, and U Th isotopic measurements by multi--collector inductively coupled plasma mass spectroscopy 显示文摘 | Cheng H Edwards R L Shen C C Po Asrnerom Y Woodhed J Hellstrom J Wang Y Kon6 X Spotl C Wang X Alexander Jr E C | 2013 | Earth and Planetary Science Letters2013，3713，72： | 1 |
| 17 | Roads and Their MajorEcological Effects显示文摘 | FORMAN R T T ALEXANDER L E | 1998 | Annual review of ecology and systematics1998，29，： | 1 |
| 18 | Mode of delivery and the survival of macrosomia infants in the United States,1995-1999显示文摘 | Boulet S L Salihu H M Alexander G R | 2009 | Birth2009，33，4： | 1 |
| 19 | First-Grade Classroom Behavior: Its Short- and Long-Term Consequences for School Performance显示文摘 | Alexander K L Entwisle D R Dauber S L | 1993 | Child Development1993，，64： | 1 |
| 20 | Neoadjuvant chemotherapy for locally advanced gastric adenocarcinoma 显示文摘 | ALEXANDER H R GREM J L PASS H I | 1993 | Oncology (Huntingt)1993，7，5： | 1 |
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