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| 1 | Effectiveness of hepatitis B virus vaccination program in Egypt:Multicenter national project显示文摘AIM:To assess the effectiveness of hepatitis B virus(HBV) vaccination program among fully vaccinated children.METHODS:A national community based crosssectional study was carried out in 6 governorates representing Egypt. A total of 3600 children aged from 9 mo to 16 years who were fully vaccinated with HBV vaccine during infancy were recruited. Face to face interviews were carried out and sera were evaluated for hepatitis B surface antigen(HBsA g),anti-HBV core antibodies(total) and quantitative detection of hepatitis B surface antibody using enzyme linked immunoassays techniques. Samples positive to HBs Ag/anti-HBV core antibodies were subjected to quantitative HBV-DNA detection by real time polymerase chain reaction with 3.8 IU/L detection limit. RESULTS:Sero-protection was detected among 2059 children(57.2%) with geometric mean titers 75.4 ± 3.6 IU/L compared to 3.1 ± 2.1 IU/L among nonseroprotected children. Multivariate logistic analysis revealed that older age and female gender were the significant predicting variables for having non seroprotective level,with adjusted odds ratio 3.3,9.1and 14.2 among children aged 5 to < 10,10 to < 15 and ≥ 15 years respectively compared to those < 5 years and 1.1 among girls compared to boys with P < 0.01. HBs Ag was positive in 0.11% and breakthrough infection was 0.36% and 0.39% depending on positivity of anti-HBc and DNA detection respectively. The prevalence of HBV infection was significantly higher among children aged ≥ 7 years(0.59%) compared to 0.07% among younger children with odds ratio equal to 8.4(95%CI:1.1-64.2) and P < 0.01.The prevalence was higher among girls(0.48%) than boys(0.29%) with P > 0.05. C ON C LU S I ON :T he E gy pt ian c ompuls or y H B V vaccination program provides adequate protection. Occult HBV infection exists among apparently healthy vaccinated children. Adherence to infection control measures is mandatory. | Iman I Salama Samia M Sami Zeinab Nabil Ahmed Said Manal H El-Sayed Lobna A El Etreby Thanaa M Rabah Dalia M Elmosalami Amany T Abdel Hamid Somaia I Salama Aida M Abdel Mohsen Hanaa M Emam Safaa M Elserougy Amal I Hassanain Naglaa F Abd Alhalim Fatma A Shaaban Samia A Hemeda Nihad A Ibrahim Ammal M Metwally | 2015 | World Journal of Hepatology2015，7，22： | 2 |
| 2 | Yield and quality of maize as affected by slow-release nitrogen in newly reclaimed sand- y soil显示文摘 | Amany A B Zeidan M S Hozayn M | 2006 | American-Eurasian Journal of Agricultural & Environmental2006，1，3： | 1 |
| 3 | Production of high protein quality noodles using wheat flour fortified with different protein products from lupine显示文摘 | MAHMOUD E A M NASSEF S L AMANY BASUNY M M | 2012 | Annals of Agricultural Science2012，57，2： | 1 |
| 4 | The effect of zinc oxide and titanium dioxide nanoparticles in the comet assay with UVA photoactivation of human sperm and lymphocytes显示文摘 | Gopalan R Osman I Amani A | 2009 | Nanotoxicology2009，3，： | 1 |
| 5 | Cyanidin 3-glucoside modulated cell cycle progression in liver precancerous lesion,in vivo study显示文摘BACKGROUND Cyanidin-3-O-glucoside(cyan)exhibits antioxidant and anticancer properties.The cell cycle proteins and antimitotic drugs might be promising therapeutic targets in hepatocellular carcinoma.AIM To investigate the effect of cyan administration on cell cycle in hepatic precancerous lesion(PCL)induced by diethylnitrosamine/2-acetylaminofluorene(DEN/2-AAF)in Wistar rats.METHODS In vivo,DEN/2-AAF-induced hepatic PCL,rats were treated with three doses of cyan(10,15,and 20 mg/kg/d,for four consecutive days per week for 16 wk).Blood and liver tissue samples were collected for measurement of the followings;alpha fetoprotein(AFP)liver function and RNA panel differential expression was evaluated via real time polymerase chain reaction.Histopathological examination of liver sections stained with H&E and immunohistochemical study using glutathione S-transferase placental(GSTP)and proliferating cell nuclear antigen(PCNA)antibodies were assessed.RESULTS Cyan administration mitigated the effect of DEN/2-AFF induced PCL,decreased AFP levels,and improved liver function.Remarkably,treatment with cyan dose dependently decreased the long non-coding RNA MALAT1 and tubulin gamma 1 mRNA expressions and increased the levels of miR-125b,all of which are involved in cell cycle and mitotic spindle assembly.Of note,cyan decreased GSTP foci percent area and PCNA positively stained nuclei.CONCLUSION Our results indicated that cyan could be used as a potential therapeutic agent to inhibit liver carcinogenesis in rat model via modulation of cell cycle. | Marwa Matboli Amany H Hasanin Reham Hussein Sarah El-Nakeep Eman K Habib Rawan Ellackany Lobna A Saleh | 2021 | World Journal of Gastroenterology2021，27，14： | 1 |
| 6 | Correlation of serum lipoprotein ratios with insulin resistance in infertile women with polycystic ovarian syndrome:a case control study显示文摘 | Ghaffarzad A Amani R Mehrzad Sadaghiani M | 2016 | Int J Fertil Steril2016，10，1： | 1 |
| 7 | Canopy temperature depression associated with yield of irrigated spring wheat cultivars in a hot climate显示文摘 | Amani Iischer R A Eynolds M P | 1996 | J Agron Crop Sci1996，176，2： | 1 |
| 8 | Pre-treatment effect of different doses of soy isoflavones on spatial learning and memory in an ovariectomized animal model of Alzheimer's disease显示文摘 | Sarkaki A Amani R Badavi M | | 0，，08： | 1 |
| 9 | Amblyopia screening for first and second-grade children in Jordan显示文摘AIM:To share the results of a national screening program for amblyopia in school children in the north of Jordan.METHODS:This is a prospective national screening study for amblyopia.The program rolls first and second-grade children(6 to 7 years old) in the north of Jordan.The eye examination included:best-corrected visual acuity,cover-uncover test,and cycloplegic retinoscopy.Monocular visual acuity was tested using an ETDRS visual acuity chart without correction.Moreover,children were tested with full cycloplegic refraction when the test criteria were met.Unilateral amblyopia was defined as a best-corrected visual acuity difference of 2 or more lines.In comparison,bilateral amblyopia was defined as a best-corrected visual acuity of 20/40 or worse in the best eye.RESULTS:The prevalence of amblyopia for the total sample tested(n=17 203) was 2.78%(n=479).The most common cause of amblyopia was hypermetropia(64.45%),followed by previous ocular surgeries(15.1%),myopia(10.43%),strabismus(9.39%),and congenital cataract(0.63%).CONCLUSION:This is the first and only study,identifing modifiable risk factors in Jordanian children with amblyopia.In their first couple of years of elementary education,many Jordanian children are affected by amblyopia and pass unnoticed.A more governmental effort is needed into screening programs to improve vision in the Jordanian population. | Khalil M.Al-Salem Mohammad S.Saleem Ismat Ereifej Hamzeh M.Alrawashdeh Rayed Falah Hussein Obeidat Asma Ali Abdlmohdi Raeda Zaki Al-Momani Layal Mohammed Hammad Omar Ahmad al-Habahbeh Yaqeen M.Assassfeh Laith Ramzi Najib Al-Qsous Ashraf Hatim Adeeb Nasraween Tariq A.Al Maaitah Deya'-Aldin Muneer Hasan Aqeel Ibtehal Eyadeh Awad Alabdulrazzg Abdullah Mahmoud Mohammad Murad Amany Jehad Faleh AL-Zurqan Enas Jamal Mohammad Jaradat Slsabela Emad Suliman Aldhoon Ala'a Majed Dmour Ahmad Talal Asassfeh Jeries Ayman Halaseh Abdel Aziz Ammar Daoud Waha Ayman Alkasasbeh Kholoud GH.Matar | 2022 | International Journal of Ophthalmology(English edition)2022，15，2： | 1 |
| 10 | Effect of ovariectomy on reference memory version of Morris water maze in young adult rats显示文摘 | Sarkaki A Amani R Badavi M | 2008 | Iran Biomed J2008，12，2： | 1 |
| 11 | Stability of yam starch gels during processing显示文摘 | AMANI N G KAMENAN A ROLLAND-SABATE A | 2005 | African Journal of Biotechnology2005，4，1： | 1 |
| 12 | The pro- moter region ( - 800, - 509 ) polymorphisms of transibrming growth factor - betal (TGF - betal ) gene and recurrent spontaneous abortion 显示文摘 | AMANI D KHAIILNEZHAD A GHAD ERI A | 2004 | J Reprod Immunol2004，62，12： | 1 |
| 13 | Removal of toxic chromium from wastewater using green alga Ulva lactuea and its activated carbon显示文摘 | El-Sikaily Amany El Nemr A Khaled A | 2007 | Journal of Hazardous Materials2007，148，12： | 1 |
| 14 | Canopy temperature depression associated with yield of irrigated spring wheat cultivation a hot climate显示文摘 | AMANI I FISCHER R A REYNOLDS M P | 1996 | Journal of Agronomy and Crop Science1996，176，2： | 1 |
| 15 | Neuroprotection by misoprostol against rotenone-induced neurotoxicity in rat brain显示文摘Objective: To investigate the effect of the prostaglandin E1 analogue misoprostol on oxidative stress and neurodegeration caused by subcutaneous rotenone administration in rats. Methods:Rotenone was administered in a dose of 1.5 mg/kg every other day for 2 weeks. Starting from the 1 st day of rotenone injection, rats were subcutaneously treated with misoprostol at doses of10, 100 or 1 000 μg/kg. Rats were evaluated for brain lipid peroxidation(malondialdehyde:MDA), reduced glutathione(GSH), nitric oxide(NO) levels, and paraoxonase-1(PON-1) activity.The concentrations of the anti-apoptotic protein B cell/lymphoma-2(Bcl-2) were determined in the striatum. Histopathologic examination and the expression of inducible nitric oxide synthase(iNOS) in the cerebral cortex and striatum were also performed. Results: Compared with the vehicle-treated group, rotenone caused a significant increase in brain lipid proxidation(MDA)by 61%(P<0.05) accompanied by an increase in NO by 73.1%(P<0.05) and a decrease in GSH concentration by 29.4%(P<0.05). In addition, brain PON-1 activity significantly decreased by63.0%(P<0.05) and striatal Bcl-2 significantly decreased by 27.9%(P<0.05) with respect to the corresponding control value. Brain sections from rotenone treated rats showed extensive dark pyknotic and apoptotic nuclei in neurons, shrunken cytoplasm and perineuronal vacuolation.Rotenone also caused pronounced expression of iNOS in the cerebral cortex and striatum.Treatment with misoprostol at doses of 100 and 1 000 μg/kg resulted in decreased brain MDA(by 16.5%-23.0%)(P<0.05) and NO levels(by 37.1%-40.7%)(P<0.05) and increased GSH concentrations(by 18.8%-30.1%)(P<0.05). PON-1 activity was significantly increased by80.0%-114.8%(P<0.05) by misoprostol at 100 and 1 000 μg/kg, respectively. In addition,misoprostol treatment restored striatal Bcl-2 concentrations to its normal value. Misoprostol treatment resulted in markedly reduced brain injury and decreased iNOS expression in the cerebral cortex and striatum of rotenone intoxicated rats. Conclusions: These data suggest that misoprostol prevents the rotenone-induced neurodegeneration in rat brain by reducing brain oxidative stress. | Omar M.E.Abdel-Salam Amany A Sleem Eman R Youness Nadia A Mohammed Enayat A Omara | 2018 | Asian Pacific Journal of Tropical Medicine2018，11，1： | 1 |
| 16 | Gemeitabine plus oxalila tin(GEMOX) combined with cetuximah in patients with progres sive advanced stage hepatocellular carcinoma: results of a multi center phase 2 study显示文摘 | Amani A Laetitia F Olivier R | 2008 | Cancer2008，112，12： | 1 |
| 17 | Hepatoprotective and antioxidant activities of Tamarix nilotica flowers显示文摘 | Sameh A Z Amany S | 2011 | Pharmaceutical Biology2011，49，4： | 1 |
| 18 | Cadmium induced changes in pigment contention up-take, proline content and phosphoenolpyruvate carboxylase activity in Triticum aestivum seedlings 显示文摘 | AMANI A L | 2008 | Australian Journal of Basic and Applied Sciences2008，2，1： | 1 |
| 19 | Canopy temperature depression association with yield of irrigated spring wheat cultivars in a hot climate显示文摘 | Amani I Fischer R A Reynolds M P | 1996 | Journal of Agronomy and Crop Science1996，176，： | 1 |
| 20 | Effect of riscumalbum on acute hepatic damage caused by carbon tetrachloride inrats显示文摘 | OMAR M A AMANY A NERMEEN M | 2010 | Turk J Med Sci2010，40，3： | 1 |
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