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4篇 您的检索式:作者名="Amy Taylor"
    题名 作者 年代 出处 被引量
1Recognizing Hospitalized Heart Failure as an Entity and Developing New Therapies to Improve Outcomes显示文摘Mihai Gheorghiade Ami N. Shah Muthiah Vaduganathan Javed Butler Robert O. Bonow Giuseppe M.C. Rosano Scott Taylor Stuart Kupfer Frank Misselwitz Arjun Sharma Gregg C. Fonarow 2013Heart Failure Clinics2013,,:1
2Can short-term fasting protect against doxorubicin-induced cardiotoxicity?显示文摘Doxorubicin(Dox) is one of the most effective chemotherapeutic agents used in the treatment of several types of cancer. However the use is limited by cardiotoxicity. Despite extensive investigation into the mechanisms of toxicity and preventative strategies, Dox-induced cardiotoxicity still remains a major cause of morbidity and mortality in cancer survivors. Thus, continued research into preventative strategies is vital. Short-term fasting has proven to be cardioprotective against a variety of insults. Despite the potential, only a few studies have been conducted investigating its ability to prevent Dox-induced cardiotoxicity. However, all show proof-of-principle that short-term fasting is cardioprotective against Dox. Fasting affects a plethora of cellular processes making it difficult to discern the mechanism(s) translating fasting to cardioprotection, but may involve suppression of insulin and insulin-like growth factor-1 signaling with stimulated autophagy. It is likely that additional mechanisms also contribute. Importantly, the literature suggests that fasting may enhance the antitumor activity of Dox. Thus, fasting is a regimen that warrants further investigation as a potential strategy to prevent Dox-induced cardiotoxicity. Future research should aim to determine the optimal regimen of fasting, confirmation that this regimen does not interfere with the antitumor properties of Dox, as well as the underlying mechanisms exerting the cardioprotective effects.Amie J Dirks-Naylor Samir A Kouzi Sendra Yang Ngan TK Tran Joseph D Bero Raean Mabolo Diep T Phan Stephanie D Whitt Heather N Taylor 2014World Journal of Biological Chemistry2014,5,3:1
3Value of peripheral vascular endothelial function in the detection of relative myocardial ischemia in asymptomatic type 2 diabetic patients who underwent myocardial perfusion imaging显示文摘Georgios I. Papaioannou Christos Kasapis Richard L. Seip Neil J. Grey Deborah Katten Frans J. Th. Wackers Silvio E. Inzucchi Samuel Engel Amy Taylor Lawrence H. Young Deborah A. Chyun Janice A. Davey Ami E. Iskandrian Robert E. Ratner Evelyn C. Robinson S 2006Journal of Nuclear Cardiology2006,,3:1
4Structural analysis of protein inclusion bodies by Fourier transform infrared microspectroscopy显示文摘Ami D Natalello A Taylor G 2006Biochim Biophys Acta2006,1764,4:1
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