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| 1 | Clinical scenarios for the use of S100β as a marker of hepatic encephalopathy显示文摘AIM: To evaluate the association between serum concentrations of S100β in patients with cirrhosis and the presence of low grade hepatic encephalopathy(HE).METHODS: This was a cross-sectional study. The population was categorized into four groups healthy subjects, cirrhosis without HE, cirrhosis with covert hepatic encephalopathy(CHE) and cirrhosis with overt HE. Kruskal-Wallis, Mann Whitney's U with Bonferroni adjustment Spearman correlations and area under the ROC were used as appropriate.RESULTS: A total of 61 subjects were included, 46 cirrhotic patients and 15 healthy volunteers. S100β values were different among all groups, and differences remained significant between groups 1 and 2(P < 0.001), and also between groups 2 and 3(P = 0.016), but not between groups 3 and 4. In cirrhotic patients with HE S100β was higher than in patients without HE [0.18(0.14-0.28) ng/m L vs 0.11(0.06-0.14) ng/m L, P < 0.001]. There was a close correlation between serum concentrations of S100β and psychometric hepatic encephalopathy score in patients with cirrhosis without HE compared to the patients with cirrhosis with CHE(r =-0.413, P = 0.019). ROC curve analysis yielded > 0.13 ng/m L as the best cutoff value of S100β for the diagnosis of HE(sensitivity 83.3%, specificity 63.6%).CONCLUSION: Serum concentrations of S100β are higher in patients with cirrhosis than in healthy volunteers, and are further increased in the presence of hepatic encephalopathy. The results suggest that serum biomarkers such as S100β could help in the correct characterization of incipient stages of HE. | Andrés Duarte-Rojo Astrid Ruiz-Margáin Ricardo U Macias-Rodriguez Francisco Javier Cubero José Estradas-Trujillo Rosa Ma Munoz-Fuentes Aldo Torre | 2016 | World Journal of Gastroenterology2016，22，17： | 4 |
| 2 | The pharmacokinetics of 750 μg levonorgestrel following administration of one single dose or two doses at 12 - or 24 -h in terval 显示文摘 | DOMINIQUE T ERIN G ANDRE U | 2001 | Contraception2001，64，3： | 1 |
| 3 | Effects of hydrogen peroxide and nitric oxide on both salt and heat stress tolerance in rice显示文摘 | Akio U Andre T J Takashi H | 2002 | Plant Science2002，163，3： | 1 |
| 4 | Analysis of chatter vibration phenomena of rolling mills using finite element methods 显示文摘 | GUO R M ANDRE C U JERRY H | 1993 | Iron and Steel Engineer1993，70，1： | 1 |
| 5 | Development of cermet microstructures during sintering显示文摘 | Zackrisson J Andrén H O Rolander U | 2001 | Metallurgical and Materials Transactions A2001，32，1： | 1 |
| 6 | Right ventricular function by strain echocardiography显示文摘 | Andre L Ruxandra J Jens U | | Current Opinion in Cardiology0，，： | 1 |
| 7 | A new deformable cat- enary element for the analysis of cable net structures显示文摘 | ANDRE A U GIL L ROCA P | 2006 | Computers & Structures2006，84，2930： | 1 |
| 8 | Profiling of com- plex mierobial populations by denaturing gradient gel eleetro- phoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA显示文摘 | GERARD M ELLEN C D W ANDRE G U | 1993 | Applied and Environmental Microbi- ology1993，59，3： | 1 |
| 9 | Analysis of the Arabidopsis shoot meristem transcfiptome during floral transition identifies distinct regulatory patterns and a leucine-rich repeat protein that promotes flowering 显示文摘 | Torti S Fornara F Vincent C Andres F NordstrOm K GObel U Knoll D Schoof H Coupland G | 2012 | Plant Cell2012，24，： | 1 |
| 10 | Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA显示文摘 | Muyzer G Ellen C D W Andre G U | 1993 | Appl Environ Microbiol1993，59，： | 1 |
| 11 | On the specific filtration mechanism of a mesoporous silica membrane, prepared with non-connecting parallel pores显示文摘 | C'edric Boissi'ere Marco U Martines Andr'e Larbot | 2005 | J Membr Sci2005，251，： | 1 |
| 12 | Mid and Late Holocene Fluvial Dynamics in the Tropical Guapi- Macacu Catchment, Southeast Brazil: The Role of Cli mate Change and Human Impact显示文摘 | ANDRE K NEHREN U BEHLING H | 2015 | Palaeogeography Palaeoclimatology Palaeoecology2015，426，： | 1 |
| 13 | Response to Salinity of three grain legumes for potential cultivation in arid areas显示文摘 | RA(U)L L ANDR(E)S O ARMANDO L | 2003 | Soil Science Plant Nutrition2003，49，3： | 1 |
| 14 | lym- phoplasmacytic lymphoma-Waldenstrom's macroglobulinemia 显示文摘 | VITOLO U FERRERI ANDRES J M MONTOTO S | 2008 | Critical Reviews in Oncology/Hematology2008，67，2： | 1 |
| 15 | Profiling of complex microbial population by denaturing gradient gel electrophoresis analysis of polymerase chain amplified reaction genes encoding for 16S rRNA 显示文摘 | Muyzer G Ellen C W Andre G U | 1993 | Appl Environ Microbiol1993，59，： | 1 |
| 16 | Development and Prospects of Mineral Liberation by Electrical Pulses 显示文摘 | ANDRES U | 2010 | International Journal of Mineral Processing2010，97，14： | 1 |
| 17 | Stabilization of foams with inorganic colloidal particles显示文摘 | Gonzenbach U T Studart Andre R Tervoort Elena | 2006 | Langmuir2006，22，10： | 1 |
| 18 | Treatment of peri-implant mucositis using a glycine powder air-polishing or ultrasonic device:a randomized clinical trial显示文摘 | Riben-Grundstrom C Norderyd O AndréU | 2015 | J Clin Periodontol2015，42，5： | 1 |
| 19 | The modified cramer-rao bound and its application to synchronization problems 显示文摘 | D'Andres A N Mengali U Reggiannini R | 1994 | IEEE Transactions on Communications1994，42，24： | 1 |
| 20 | Development of cermet microstructures during sintering显示文摘 | Zackrisson J Andrén H O Rolander U | 2001 | Metallurgical and Materials Transactions A2001，32，1： | 1 |
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