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| 1 | 膳食中钠(盐)与血压的关系及其他膳食因素可能的调节作用显示文摘现有资料表明,膳食钠(盐)与血压直接相关。以往大多数研究结果来自缺乏膳食数据的研究;因此,这种钠-血压关系是否受其他膳食因素调节尚不清楚。国际宏量/微量营养素和血压研究(international study on macro/micronutrients and blood pressure,INTERMAP)结果显示,在控制多种非膳食因素情况下,年龄40~59岁的男性和女性4680人(中国、日本、英国和美国的17个人口样本)的血压与24h尿钠排泄和尿钠/钾直接相关。 | 刘莉 叶鹏 Stamler J Chan Q Daviglus ML Dyer AR Van Horn L Garside DB Miura K Wu Y Ueshima H Zhao L Elliott P INTERMAP Research Group | 2018 | 中华高血压杂志2018，26，4： | 8 |
| 2 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017，16，6： | 8 |
| 3 | DDGS和酵母培养物对奶牛生产性能和乳成分的影响显示文摘选择16头泌乳天数为127±52d经产荷斯坦泌乳牛用于评价酵母培养物(达农威益康XP)和玉米酒糟及其可溶物(DDGS)在试验日粮中含有限草料纤维数量(草料中的中性洗涤纤维含量为19.3%,干物质基础)之情况下对产奶量和乳成分的影响及其它们之间的互作效应。本次试验采用4重复4×4拉丁方设计,试验时间为4个星期。处理组均按照2×2因子排列而设定,其中:1)日粮中不含酵母培养物和DDGS(对照组);2)日粮中含有20%DDGS,无酵母培养物(DDGS组);3)日粮中含有60g/d的酵母培养物益康XP(XP组);4)日粮中含有20%DDGS和60g/d的益康XP(XP+DDGS组)。本次试验结果表明:各处理组之间对奶牛体重和体况评分无显著的影响。日粮的处理并不影响干物质采食量(DMI),在使用草料纤维含量较低且添加20%DDGS的日粮情况下乳脂率会降低。添加益康XP的确能够提高产奶量及乳蛋白产量,但却不能够完全阻止因DDGS所造成的乳脂率下降的趋势。无论日粮中是否含有DDGS,益康XP都能够提高奶牛的生产性能。 | AR Hippen DJ Schingoethe KF Kalscheur P Linke K Gross DR Rennich IIkye Yoon 徐明 | 2010 | 中国奶牛2010，，8： | 4 |
| 4 | Novel approaches in schizophrenia-from risk factors and hypotheses to novel drug targets显示文摘Schizophrenia is a severe psychiatric disorder characterized by emotional,behavioral and cognitive disturbances, and the treatment of schizophrenia is oftencomplicated by noncompliance and pharmacoresistance. The search for thepathophysiological mechanisms underlying schizophrenia has resulted in theproposal of several hypotheses to explain the impacts of environmental, genetic,neurodevelopmental, immune and inflammatory factors on disease onset andprogression. This review discusses the newest insights into the pathophysiologyof and risk factors for schizophrenia and notes novel approaches in antipsychotictreatment and potential diagnostic and theranostic biomarkers. The currenthypotheses focusing on neuromediators (dopamine, glutamate, and serotonin),neuroinflammation, the cannabinoid hypothesis, the gut-brain axis model, andoxidative stress are summarized. Key genetic features, including small nucleotidepolymorphisms, copy number variations, microdeletions, mutations andepigenetic changes, are highlighted. Current pharmacotherapy of schizophreniarelies mostly on dopaminergic and serotonergic antagonists/partial agonists, butnew findings in the pathophysiology of schizophrenia have allowed theexpansion of novel approaches in pharmacotherapy and the establishment ofmore reliable biomarkers. Substances with promising results in preclinical andclinical studies include lumateperone, pimavanserin, xanomeline, roluperidone,agonists of trace amine-associated receptor 1, inhibitors of glycine transporters,AMPA allosteric modulators, mGLUR2-3 agonists, D-amino acid oxidase inhibitorsand cannabidiol. The use of anti-inflammatory agents as an add-on therapy ismentioned. | MatejĽupták Danica Michaličková Zdeněk Fišar Eva Kitzlerová Jana Hroudová | 2021 | World Journal of Psychiatry2021，11，7： | 3 |
| 5 | A shunt active power filter applied to high voltage distribution lines显示文摘 | HAFNER J AREDS M HEUMANN K | 1997 | IEEE Trans on Power Delivery1997，12，1： | 1 |
| 6 | Risk factors for peripheral arterial disease incidence in persons with diabetes: the Atherosclerosis Risk in Communities (ARIC) Study显示文摘 | Wattanakit K Folsom AR Selvin E | 2005 | Atherosclerosis2005，180，2： | 1 |
| 7 | Secondary elevation of extra cellular neuro transmitter aminoacids in the reperfusion phase following focal cerebral ischemia显示文摘 | Matsumoto K Lo EH Pierce AR | 1996 | J Cereb Blood Flow Metab1996，16，1： | 1 |
| 8 | Difereneesin inflammatory eytokine and Toll - like receptor genes and bacterial vaginosis in pregnancy 显示文摘 | Goepfert AR Vamer M Ward K | 2005 | Am J Obstet Gynecol2005，193，： | 1 |
| 9 | HIV seroeonversion in intravenous drug users in San Francisco, 1985 - 1990 显示文摘 | Moss AR Vranizan K Gorter R | 1994 | AIDS1994，8，2： | 1 |
| 10 | The surgical management of thoracolumbar injuries 显示文摘 | Singh K Vaccaro AR Eichenbaum MD | 2004 | J Spinal Cord Med2004，27，2： | 1 |
| 11 | The origin of annular junctions: a mechanism of gap junction internalization显示文摘 | Jordan K Chodock R Hand AR | 2001 | J Cell Sci2001，114，4： | 1 |
| 12 | P2 receptors modulate respiratory rhythm but do not contribute to central CO2 sensitivity in vitro显示文摘 | Lorier AR Peebles K Brosenitsch T | 2004 | Respiratory Physiology & Neurobiology2004，142，： | 1 |
| 13 | Rotavirus nonstructural glycoproein NSP4 alters plasma membrane permeability in mammalian cells显示文摘 | Newton K Meyer TC Bellamy AR | 1997 | J Virol1997，71，12： | 1 |
| 14 | Reconstruction with autologo-us pasteurized whole knee joint I:experimental study in a rabbit model显示文摘 | Ahmed AR Watanabe H Takagishi K | 2003 | J Orthop Sci2003，8，2： | 1 |
| 15 | Effect of fluid and sodium removal on mortality in peritoneal dialysis patients显示文摘 | Ares K Nergizoglu G Keven K | 2001 | Kidney Int2001，60，： | 1 |
| 16 | Enhancement of sta- bility following anterior cervical corpectomy: a biome- chanical study 显示文摘 | Singh K Vaccaro AR Kim J | 2004 | Spine ( Phila Pa 1976 )2004，29，8： | 1 |
| 17 | Macrophage migrationinhibitory factor promotes cell death and aggravates neurologicdeficits after experimental stroke 显示文摘 | Inacio AR Ruscher K Leng L | 2011 | J Cereb Blood FlowMetab2011，31，4： | 1 |
| 18 | Overexpression of caveolln- I inhibits endothelial cell proliferation by arresting the cell cycle at G0/G1 phase 显示文摘 | Fang K Fu W Beardsley AR | 2007 | Cell Cycle2007，6，2： | 1 |
| 19 | Ketamine: from medicine to misuse 显示文摘 | Wolff K Winstock AR | 2006 | CNS Drugs2006，20，3： | 1 |
| 20 | Methadone ameliorates multiple-low-dose streptozotocin- induced type 1 diabetes in mice 显示文摘 | Amirshahrokhi K Dehpour AR Hadjati J | 2008 | Toxicol Appl Pharm2008，232，： | 1 |
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