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| 1 | Cardiometabolic health among gastric bypass surgery patients with polycystic ovarian syndrome显示文摘AIM:To examine the effect of gastric bypass surgery on cardiometabolic health among women with polycystic ovarian syndrome(PCOS).METHODS:Retrospective medical chart review identified women(n = 389) with PCOS who underwent Roux-en-Y gastric bypass surgery from 2001-2009 in one surgical practice.Separate repeated measures linear mixed models were fit using the MIXED procedureto assess mean change in cardiometabolic disease risk factors from before to 1-year after surgery and were evaluated by ethnicity [Hispanic,non-Hispanic black(NHB) and white(NHW)].RESULTS:The majority of the sample was Hispanic(66%,25% NHB,9% NHW).Mean body mass index significantly improved 1 year post-surgery for all ethnic groups(45.5 to 35.5 kg/m2 for Hispanics,46.8 to 37.7 kg/m2 for NHB and 45.7 to 36.7 kg/m2 for NHW,P < 0.001).Among Hispanic women mean total cholesterol(198.1 to 160.2 mg/dL),low-density lipoproteins(LDL) cholesterol(120.9 to 91.0 mg/dL),triglycerides(148.6 to 104.8 mg/dL),hemoglobin A1c(6.2% to 5.6%),alanine aminotransferase(28.1 to 23.0 U/L) and aspartate aminotransferase(23.5 to 21.6 U/L) decreased significantly(P < 0.001).Among NHB,mean total cholesterol(184.5 to 154.7 mg/dL),LDL cholesterol(111.7 to 88.9 mg/dL) and triglycerides(99.7 to 70.0 mg/dL) decreased significantly(P < 0.05).Among NHW,mean total cholesterol(200.9 to 172.8 mg/dL) and LDL cholesterol(124.2 to 96.6 mg/dL),decreased significantly(P < 0.05).Pairwise ethnic group comparisons of all cardiometabolic outcomes adjusted for age and type of surgery before and 1 year after surgery showed no statistical difference between the three groups for any outcome.CONCLUSION:Cardiometabolic disease risk improvements vary by ethnicity and obesity may impact glucose tolerance and liver function changes more in Hispanic women with PCOS vs non-Hispanic women. | Carley A Gomez-Meade Adriana Carrillo Gabriela Lopez-Mitnik Sarah E Messiah Kristopher L Arheart Nestor de la Cruz-Muoz | 2013 | World Journal of Diabetes2013，4，3： | 6 |
| 2 | Obesity and cardiometabolic disease risk factors among US adolescents with disabilities显示文摘AIM: To generate prevalence estimates of weight status and cardiometabolic disease risk factors among adolescents with and without disabilities.METHODS: Analysis of the 1999-2010 National Health and Nutrition Examination Survey data was conducted among 12-18 years old with(n = 256) and without disabilities(n = 5020). Mean values of waist circumference, fasting glucose, high-density-lipoprotein cholesterol, triglycerides, systolic and diastolic blood pressure and metabolic syndrome(Met S, ≥ 3 risk factors present) were examined by the following standardized body mass index(BMI) categories for those with and without disabilities; overweight(BMI ≥ 85th- < 95 th percentile for age and sex), obesity(BMI ≥ 95 th percentile) and severe obesity(BMI ≥35 kg/m2). Linear regression models were fit with each cardiometabolic disease risk factor independently as continuous outcomes to show relationships with disability status. RESULTS: Adolescents with disabilities were significantlymore likely to be overweight(49.3%), obese(27.6%) and severely obese(12%) vs their peers without disabilities(33.1%, 17.5% and 3.6%, respectively, P ≤ 0.01 for all). A higher proportion of overweight, obese and severely obese children with disabilities had abnormal SBP, fasting lipids and glucose as well as Met S(18.9% of overweight, 32.3% of obese, 55% of severely obese) vs their peers without disabilities(9.7%, 16.8%, 36.3%, respectively). US adolescents with disabilities are over three times as likely to have Met S(OR = 3.45, 95%CI: 1.08-10.99, P = 0.03) vs their peers with no disabilities.CONCLUSION: Results show that adolescents with disabilities are disproportionately affected by obesity and poor cardiometabolic health vs their peers with no disabilities. Health care professionals should monitor the cardiometabolic health of adolescents with disabilities. | Sarah E Messiah Denise C Vidot Gabriel Somarriba Kanathy Haney Semra Aytur Ruby A Natale Jeffrey P Brosco Kristopher L Arheart | 2015 | World Journal of Diabetes2015，6，1： | 2 |
| 3 | Secondhand smoke exposure and C-reactive protein levels in youth 显示文摘 | Wilkinson JD Lee D J Arheart KL | 2007 | Nicotine Tob Res2007，9，2： | 1 |
| 4 | Low circulating folate and vitamin B6 concentrations: risk factors for stroke, peripheral vascular disease, and coronary artery disease显示文摘 | Robinson K Arheart K Refsum H | 1998 | Cir culation1998，97，： | 1 |
| 5 | Mieroemboli in aneurysmal suharachnoid hemorrhage显示文摘 | Romano JG Rabinstein AA Arheart KL | 2008 | J Neuroimaging2008，18，： | 1 |
| 6 | Single serum progesterone as a screen for ectopic pregnancy:exchanging specificity and sensitivity to obtain optimal test performance显示文摘 | McCord ML Arheart KL Muram D | 1996 | Fertil Steril1996，66，4： | 1 |
| 7 | Low circulation folate and vitamin B6 concentrations risk factors for stroke,peripheral vascular disease,and coronary artery disease显示文摘 | Robinson K Arheart K Refsum H | 1998 | Circulation1998，97，4： | 1 |
| 8 | Reduction of homocysteine levels in coronary artery disease by low-dose folic acid combined with vitamins B6 and B12显示文摘 | Lobo A Naso A Arheart K | 1999 | Am J Cardiol1999，83，6： | 1 |
| 9 | Suppression of insulin secretion is associated with weight loss and altered maeronu- trient intake and preference in a subset of obese adults 显示文摘 | Velasqnez - Mieyer PA Cowan PA Arheart KL | 2003 | Int J Obes Relat Metab Disord2003，27，2： | 1 |
| 10 | CYP2D6 poor metabolizer genolype and smoking predict severe postoperative pain in female patients on arrival Io the rec~ovet'y room显示文摘 | Yang Z Yang Z Arheart KL el aI | 2012 | Pain Med2012，13，4： | 1 |
| 11 | Evaluation of all immunosuppressant side effect instrument显示文摘 | Winsett RP Arheart K Stratta RJ | 2004 | Prog Transplant2004，14，3： | 1 |
| 12 | CYP2D6 poor metabolizer genotype and smoking predict severe postoperative pain in female patients on arrival to the recovery room 显示文摘 | Yang Z Arheart KL Morris R | 2012 | Pain Med2012，13，4： | 1 |
| 13 | Low circulating folate and vitamin B6 concentrations :risk factors for stroke,peripheral vascular disease,and coronary artery disease 显示文摘 | Robinson K Arheart K Refsum H | 1998 | Circulation1998，97，： | 1 |
| 14 | Reduction of homocysteine levels in coronary artery disease by low-dose folic acid combined with vitamins B6 and B12显示文摘 | LOBO A NASO A ARHEART K | 1999 | Am J Cardiol1999，83，6： | 1 |
| 15 | Low circu- lating folate and vitamin B6 concentrations,risk fac- tors for stroke,peripheral vasealar disease and coro- nary artery disease European COMAC Group 显示文摘 | Robinson K Arheart K Refsum H | 1998 | Circulation1998，97，5： | 1 |
| 16 | Bariatricsurgery significantly decreases the prevalence of type 2 diabetes melli-tus and pre-diabetes among morbidly obese multiethnic adults:long-term results显示文摘 | de la Cruz-Munoz N Messiah S E Arheart K L | 2011 | J Am Coll Surg2011，212，4： | 1 |
| 17 | Reduction of homocysteine levels in coronary artery disease by low-dose folic acid combined with vitamins B6 and B12 显示文摘 | Lobo A Naso A Arheart K | 1999 | Am J Cardiol1999，83，： | 1 |
| 18 | Low circulating folateand vitamin B6 concentrations : risk factors for stroke, peripheral vascular disease coronary artery disease 显示文摘 | Robinson K Arheart K Refsum H | 1998 | Circulation1998，97，5： | 1 |
| 19 | Evaluation of an immunosuppressant side effect instrument显示文摘 | Winsett RP Arheart k Stratta RJ | 2004 | Prog Transplant2004，14，3： | 1 |
| 20 | Bariatric surgery significantly decreases the prevalence of type 2 diabetes mellitus and pre- diabetes among morbidly obese multiethnic adults:Long -term results显示文摘 | De la Cruz - Mufioz N Messiah SE Arheart KL | 2011 | J Am Coil Surg2011，212，4： | 1 |
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