|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Advances in nutritional therapy in inflammatory boweldiseases:Review显示文摘Inflammatory bowel diseases(IBD), including ulcerative colitis and Crohn's disease are chronic, life-long, and relapsing diseases of the gastrointestinal tract. Currently, there are no complete cure possibilities, but combined pharmacological and nutritional therapy may induce remission of the disease. Malnutrition and specific nutritional deficiencies are frequent among IBD patients, so the majority of them need nutritional treatment, which not only improves the state of nutrition of the patients but has strong anti-inflammatory activity as well. Moreover, some nutrients, from early stages of life are suspected as triggering factors in the etiopathogenesis of IBD. Both parenteral and enteral nutrition is used in IBD therapy, but their practical utility in different populations and in different countries is not clearly established, and there are sometimes conflicting theories concerning the role of nutrition in IBD. This review presents the actual data from research studies on the influence of nutrition on the etiopathogenesis of IBD and the latest findings regarding its mechanisms of action. The use of both parenteral and enteral nutrition as therapeutic methods in induction and maintenance therapy in IBD treatment is also extensively discussed. Comparison of the latest research data, scientific theories concerning the role of nutrition in IBD, and different opinions about them are also presented and discussed. Additionally, some potential future perspectives for nutritional therapy are highlighted. | Andrzej Wędrychowicz Andrzej Zając Przemysław Tomasik | 2016 | World Journal of Gastroenterology2016，22，3： | 21 |
| 2 | Ghrelin and gastrin in advanced gastric cancer before and after gastrectomy显示文摘AIM: To investigate plasma ghrelin, gastrin and growth hormone secretagogue receptor (GHS-R) expression in advanced gastric cancer (GC) before and after resection. METHODS: Seventy subjects in whom endoscopy of the upper gastrointestinal tract was performed in the Department of General Surgery at Cracow University during the past decade: (1) 25 patients with GC associated with Helicobacter pylori (H. pylori) infection; (2) 10 patients with GC 4-5 years after (total or subtotal) gastrectomy; (3) 25 healthy H. pylori-negative controls, matched by age and BMI to the above two groups; and (4) 10 GC patients 4-5 years after total gastrectomy. Ghrelin and gastrin plasma concentrations were measured by specific radioimmunoassay under fasting conditions and postprandially at 60 and 90 min after ingestion of a mixed meal. GHS-R expression was examined in biopsy samples from intact healthy mucosa and GC tissue using semi-quantitative reverse transcription-polymerase chain reaction. RESULTS: In healthy controls, fasting plasma ghrelin levels were significantly elevated and declined markedly at 60 and 90 min after a mixed meal. The concomitant enhanced ghrelin, GHS-R and gastrin expression in GC tissue over that recorded in intact mucosa, and the marked rise in plasma gastrin in these subjects under fasting conditions indicate the role of these hormonal factors in GC formation. Fasting plasma levels and postprandial response of ghrelin and gastrin appear to be inversely correlated in healthy subjects. Feeding in the controls resulted in a significant fall in plasma ghrelin with a subsequent rise in plasma gastrin, but in H. pylori-positive GC patients submitted to total or distal gastrectomy, feeding failed to affect significantly the fall in plasma ghrelin that was recorded in these patients before surgery. Fasting ghrelin concentrations were significantly lower in patients 4-5 years after total gastrectomy compared to those in healthy controls and to these in GC patients before surgery. CONCLUSION: Elevated plasma gastrin and suppression of fasting ghrelin in patients with GC suggest the existence of a close relationship between these two hormones in gastric carcinogenesis. | Anna Zub-Pokrowiecka Kazimierz Rembiasz Peter C Konturek Andrzej Budzyński Stanisaw J Konturek Marek Winiarski Wadysaw Bielański | 2011 | World Journal of Gastroenterology2011，17，4： | 7 |
| 3 | Korean pine nut fatty acids affect appetite sensations,plasma CCK and GLP 1 in overweight subjects 显示文摘 | Einerhand AW Pasman W Rubingh C | 2006 | FASEB J2006，20，： | 1 |
| 4 | New 3-((2′:2',5':2''-terthiophene)-3 '-yl) acrylic acid as active layer for organic fieldeffect transistor显示文摘 | SALIM N T AW K C PENG H | 2008 | Mater Chem Phys2008，111，1： | 1 |
| 5 | Circulation CXCL16 is not related to circulation ox LDL in patients with rheumatoid arthritis 显示文摘 | van Lieshout AW Popa C Meyer-Wentrup F | 2007 | Boochem Biophys Res Commun2007，355，2： | 1 |
| 6 | PAK signaling regulates oxidant-dependent NF-κB activation by flow显示文摘 | Orr AW Hahn C Blackman B R | | 0，，06： | 1 |
| 7 | Carotid artery plaque burden, stiffness, and mortality risk in elderly men: a prospective, population-based cohort study显示文摘 | Stork S van den Beld AW von Schacky C | 2004 | Circulation2004，110，3： | 1 |
| 8 | Vitamin D3 improves glucose folerance and insulin secretion in vitamin D - deficent rat in vivo 显示文摘 | Cade C Norman AW | 1986 | Endocrinology1986，119，： | 1 |
| 9 | Transthoracic echo- cardiographic predictors of left atrial hypertension in patients on venoarterial extracorporeal membrane oxygenation 显示文摘 | Eckhauser AW Jones C Witte MK | 2014 | World J Pediatr Congenit Heart Surg2014，5，1： | 1 |
| 10 | Premiere use of IntegraTM artificial skin to close an extensive fetal skin defect during open in utero repair of myelomeningocele显示文摘 | Meuli M Meuli-Simmen C Flake AW | 2013 | Pediatr Surg Int2013，29，12： | 1 |
| 11 | CREB-binding protein is a mediator of neuroblastoma cell death induced by the histone deacetylase inhibitor trichostatin A显示文摘 | Subramanian C Jarzembowski JA Opipari AW Jr | 2007 | Neoplasia2007，9，6： | 1 |
| 12 | Regional trabecular bone matrix degeneration and osteocyte death in femora of glucocorticoid-treated rabbits显示文摘 | EBERHARDT AW YEAGER-JONES A BLAIR H C | 2001 | Endocrinology2001，142，3： | 1 |
| 13 | Retival VEGF mRNA measured by SYBR green Ⅰ fluorescence: A versatile approach to quantitative PCR显示文摘 | Simpson DA Feeney S Boyle C Stitt AW | 2000 | Mol Vis2000，6，10： | 1 |
| 14 | Autoimmune thrombocytopenia in non-Hodgkin' s lymphomas 显示文摘 | Hauswirth AW Skrabs C Schotzinger C | 2008 | Hematology2008，93，3： | 1 |
| 15 | Right ventricular septal pacing:a comparative study of outflow tract and mid ventricular sites显示文摘 | Rosso R Medi C Teh AW | 2010 | Pacing Clin Electrophysiol2010，33，10： | 1 |
| 16 | Conserved microtubμLe-actin interactions in cell movement and morphogenesis 显示文摘 | Rodriguez OC Schaefer AW Mandato C A | 2003 | Nature cell biology2003，5，7： | 1 |
| 17 | Meta-analysis of selective serotonin reuptake inhibitors in patients with depression and coronary heart disease显示文摘 | Pizzi C Rutjes AW Costa GM | 2011 | Am J Cardiol2011，107，7： | 1 |
| 18 | Ultrasoundguided strategy for provisional stenting with focal balloon combination catheter: results from the randomized Strategy for Intracoronary Ultrasound-guided PTCA and Stenting (SIPS) trial显示文摘 | Frey AW Hodgson JM Muller C | 2000 | Circulation2000，102，20： | 1 |
| 19 | Anti-hepatocyte growth factor antibody inhibits hepatocyte proliferation during liver regeneration显示文摘 | Burr AW Toole K Chapman C | 1998 | Pathol1998，185，： | 1 |
| 20 | Carotid artery plaque burden,Stif&ess, and mortaliy risk in elderly men: aprospcctive, popula-tion-based cohort study 显示文摘 | Stork S Beld AW Schacky C et ai | 2004 | Circulation2004，110，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员