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| 1 | Pyrodinium大量繁殖现象会在东南亚地区重新发生和扩散吗?——千年末的见解显示文摘迄今20年来,Pyrodinium bahamense(var.compressum)一直是造成东南亚地区重大公众健康问题和经济问题的唯一的腰鞭毛虫物种。它产生石房蛤毒素,即一系列造成麻痹性贝毒(PSP)的毒素。这是一个影响世界上许多国家的严重的毒理学问题,轻者,会在30分钟内发生中毒现象,重者,可能在食用中毒贝类后的2~24小时内由于呼吸系统麻痹而致死。在马来西亚、文莱、菲律宾以及印度尼西亚均有关于这种生物大量繁殖的报道。自1976年首次在马来西亚沙巴发生以来,东盟-加拿大赤潮网已在26个地区记录到31次该种生物大量繁殖事件。截止1999年,受影响最严重的国家是菲律宾、其受影响的地区最多、发生麻痹性贝毒(PSP)事件最多(约1995起)。马来西亚报道总共发生609起PSP事件,造成44人死亡,而文莱则记录有14起PSP事件,但没有死亡事故。印度尼西亚则记录有427起PSP事件,17人死亡。在该地区迄今没有开展关于这些大量繁殖事件对生态/环境的影响的研究。对经济影响的估算表明,损失可高达每天30万美元。有助于了解Pyrodinium大量繁殖动态的大部分信息来自于已经在受到影响的地区各国不同程度地开展的有害/有毒藻类监测与研究。区域性的合作研究与监测工作可有助于协调当地的数据集并保证其用于比较分析和模拟所要求的质量和有效性。对地方和区域尺度上大量繁殖的时间模型以及Pyrodinium大量繁殖发生/再发生和扩散的可能征兆和趋势可以进行调查。可以通过改进和优化现有的Pyrodinium大量繁殖描述性和简单的预报模型,来帮助管理这里的人民赖以为日常食物来源和生计的野生捕捞和人工养殖的贝类。 | Rhodora V. Azanza FJR Max Tayor 林宝法 | 2001 | AMBIO-人类环境杂志2001，30，6： | 5 |
| 2 | Concurrent clarithromycin and cyclosporine A treatment显示文摘 | Sádaba B López de Ocáriz A Azanza J R | 1998 | J Antimicrob Chemother1998，42，3： | 1 |
| 3 | Pharmacokinetics of tramadol enantiomers and their respective phase I metabolites in relation to CYP2D6 phenotype显示文摘 | Garcia-Quetglas E Azanza JR Sadaba B | 2007 | Pharmacol Res2007，55，2： | 1 |
| 4 | Short-term efficacy of intravitreal dobesilate in central serouschorioretinopathy 显示文摘 | Cuevas P Outeirino LA Azanza C Angulo J Gimenez-GallegoG | 2012 | Eur J Med Res2012，17，1： | 1 |
| 5 | Ibuprofen-arginine pharmacology and role in the treatment of acute pain显示文摘 | Garcia-Quetglas E Sádaba B Azanza JR | 2006 | Dolor2006，21，1： | 1 |
| 6 | Food safety knowledge and practices of street food vendors in a Philippines university campus显示文摘 | Azanza MP Gatchalian CF Ortega MP | 2000 | Int J Food Sci Nutr2000，51，4： | 1 |
| 7 | Quality of orange juice drink subjected to a predictive model-based pasteurization process 显示文摘 | GABRIEL A A AZANZA M P V | 2009 | Journal of Food Quality2009，32，4： | 1 |
| 8 | In vitro carpospore release and germination in Kappaphycus alvarezii (Dory) Doty from Tawi- Tawi, Philippines 显示文摘 | AZANZA R V ALIAZA T T | 1999 | Botanica Marina1999，42，3： | 1 |
| 9 | Molecular mappingof gibberellin- responsive dwarfing genes in bread wheat 显示文摘 | Ellis M H Rebetzke G J Azanza F | 2005 | Theoretical and Applied Genetics2005，111，3： | 1 |
| 10 | Influence of double enzymic hydrolyses on gluten functionality 显示文摘 | Mimouni B Azanza JL Raymond J | 1999 | Journal of the Science of Food and Agriculture1999，79，： | 1 |
| 11 | short-term efficacy of intravitreal dobesilate in central serous choriortinopathy 显示文摘 | Cuevas P Outeirfio LA Azanza C | 2012 | Eur J Med Res2012，17，： | 1 |
| 12 | Critical appraisal of bilastine for the treatment of allergic rhinoconjunctivitis and urticaria 显示文摘 | Sadaba B Azanza JR Gomez-Guiu A | 2013 | Ther Clin Risk Manag2013，9，4： | 1 |
| 13 | An extensive cochlodinium bloom along the Western coast of Palawan, Philippines显示文摘 | AZANZA R V DAVID L T BORJA R T BAUIA I U FUKUYO Y | 2008 | Harmful Algae2008，7，： | 1 |
| 14 | Influence of double enzymic hydrolyses on gluten functionality显示文摘 | MIMOUNI B AZANZA J L RAYMOND J | 1999 | Journal of the Science of Food and Agriculture1999，79，7： | 1 |
| 15 | Absorption coefficient of bulk and thin film Cu20显示文摘 | Claudia Malerba FrancescoBiccari Cristy Leonor Azanza Ricardo | 2011 | Solar Energe Materials and Solar Cell2011，，： | 1 |
| 16 | Quantitative trait loci influencing chemical and sensory characteristics of eating quality in sweet corn 显示文摘 | Azanza F Tadmor Y Klein B P | 1996 | Genome1996，39，： | 1 |
| 17 | Improvement in the signs and symptoms of dry eye disease with dobesilate eye drops显示文摘Background:Dry eye is a multifactor disease of the tear film and ocular surface that substantially affects quality of life.Case presentation:Dobesilate administered as eye drops was well tolerated and effective in treating both the objective signs and subjective symptoms of dry eye disease in this 2-week study.Conclusion:To the best of our knowledge,this is the first clinical report of using dobesilate in eye drops.Dobesilate may provide a novel approach to treating drying diseases of the eye. | Pedro Cuevas Luis Antonio Outeiriño Carlos Azanza Javier Angulo Guillermo Giménez-Gallego | 2016 | Journal of Medical Colleges of PLA(China)2016，31，1： | 1 |
| 18 | Molecular mapping of gibberellin responsive dwarfing genes in bread wheat 显示文摘 | Ellis M H Rebetzke G J Azanza F | 2005 | Theoretical and Applied Genetics2005，111，： | 1 |
| 19 | Quantitative trait loci influencing chemical and sensory characteristics of eating quality in sweet corn 显示文摘 | Azanza F Tadmor Y Klein B P | 1996 | Genome1996，39，1： | 1 |
| 20 | An extensive Cochlo- dinium bloom along the western coast of Palawan, Philippines 显示文摘 | AZANZA R V DAVID LT BORJA RT | 2008 | Harmful Algae2008，7，： | 1 |
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