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| 1 | Macrophage migration inhibitory factor gene polymorphisms in inflammatory bowel disease: An association study in New Zealand Caucasians and meta-analysis显示文摘AIM:To investigate the association of macrophage migration inhibitory factor(MIF)promoter polymorphisms with inflammatory bowel disease(IBD)risk.METHODS:One thousand and six New Zealand Caucasian cases and 540 Caucasian controls were genotyped for the MIF SNP-173G>C(rs755622)and the repeat polymorphism CATT5-8(rs5844572)using a predesigned TaqMan SNP assay and capillary electrophoresis,respectively.Data were analysed for single site and haplotype association with IBD risk and phenotype.Meta-analysis was employed,to assess cumulative evidence of association of MIF-173G>C with IBD.All published genotype data for MIF-173G>C in IBD were identified using PubMed and subsequently searching the references of all PubMed-identified studies.Imputed genotypes for MIF-173G>C were generated from the Wellcome Trust Case Control Consortium(and National Institute of Diabetes and Digestive and Kidney Diseases).Separate meta-analyses were performed on Caucasian Crohn’s disease(CD)(3863 patients,6031controls),Caucasian ulcerative colitis(UC)(1260 patients,1987 controls),and East Asian UC(416 patients and 789 controls)datasets using the Mantel-Haenszel method.The New Zealand dataset had 93%power,and the meta-analyses had 100%power to detect an effect size of OR=1.40 atα=0.05,respectively.RESULTS:In our New Zealand dataset,single-site analysis found no evidence of association of MIF polymorphisms with overall risk of CD,UC,and IBD or disease phenotype(all P values>0.05).Haplotype analysis found the CATT5/-173C haplotype occurred at a higher frequency in New Zealand controls compared to IBD patients(0.6 vs 0.01;P=0.03,OR=0.22;95%CI:0.05-0.99),but this association did not survive bonferroni correction.Meta-analysis of our New Zealand MIF-173G>C data with data from seven additional Caucasian datasets using a random effects model found no association of MIF polymorphisms with CD,UC,or overall IBD.Similarly,meta-analysis of all published MIF-173G>C data from East Asian datasets(416UC patients,789 controls)found no association of this promoter polymorphism with UC. | James D Falvey Robert W Bentley Tony R Merriman Mark B Hampton Murray L Barclay Richard B Gearry Rebecca L Roberts | 2013 | World Journal of Gastroenterology2013，19，39： | 9 |
| 2 | A non-oscillatory Eulerian approach to interface in multimaterial flows (ghost fluid method)显示文摘 | Fedkiw R P Aslam T Merriman B | 1999 | Journal of Computational Physics1999，152，2： | 2 |
| 3 | A non-oscillatory Eulerian approach to interfaces in multimaterial flows (the gost fuid mthod) 显示文摘 | Fedkiw R P Marquina A Merriman B | 1999 | Journal of Computational Physics1999，152，： | 1 |
| 4 | An isobaric fix for the overheating problem in muitimaterial compressible flows显示文摘 | Fedkiw R P Marquina A Merriman B | 1999 | Journal of Computational Physics1999，148，： | 1 |
| 5 | A PDE-based fast local level set method显示文摘 | Peng D Merriman B Osher S | 1999 | Journal of Computational Physics1999，155，2： | 1 |
| 6 | Autonomic shutdown of lithium-ion batteries using thermoresponsive microspheres显示文摘 | Baginska M Blaiszik B J Merriman R J | 2012 | Advanced Energy Materials2012，2，5： | 1 |
| 7 | Moti-on of Multiple Junctions,A Level Set Approach显示文摘 | Bence J Osher S | 1994 | Journal of Computational Physics1994，112，3： | 1 |
| 8 | Capturing the behavior of bubbles and drops using the variational level set approach 显示文摘 | ZHAO Hong-kai MERRIMAN B OSHER S | 1998 | Journal of Computational Physics1998，143，2： | 1 |
| 9 | A variational level set approach to multiphase motion 显示文摘 | Zhao Hong-kai Chan T Merriman B | 1996 | Journal of Computational Physics1996，127，1： | 1 |
| 10 | A non-oscillatory Eulerian approach to interfaces in multi-material Flows (the Ghost Fluid Method) 显示文摘 | Fedkiw R P Aslam T Merriman B | 1999 | Journal of Computational Physics1999，152，： | 1 |
| 11 | A level set formulation of Eulerian interface capturing methods for incompressible fluid flows显示文摘 | Chang Y C Hou T Y Merriman B | 1996 | J Camp Phys1996，124，2： | 1 |
| 12 | Implicit and nonparametric shape reconstruction from unorganized data using a variational level set method 显示文摘 | ZHAO Hong-kai OSHER S MERRIMAN B | 2000 | Computer Vision and Image Un- derstanding2000，80，3： | 1 |
| 13 | A varia- tional level-set approach to muhiphase motion 显示文摘 | ZHAO H K CHAN T MERRIMAN B | 1996 | Journal of Computational Physics1996，127，： | 1 |
| 14 | A non-oscillatory Eulerian approach to interfaces in multimaterial flows (the ghost fluid method) 显示文摘 | Fedkiw R P Aslam T Merriman B | 1999 | Journal of Computational Physics1999，152，2： | 1 |
| 15 | SeqWare query engine: storing and searching sequence data in the cloud 显示文摘 | OCONNOR B MERRIMAN B NELSON S | 2010 | BMC Bioinformatics2010，11，12： | 1 |
| 16 | A variational level set approach to multiphase motion显示文摘 | Zhao H K Chan T Merriman B | | 0，，： | 1 |
| 17 | Repetitive sequence environment distinguishes housekeeping genes显示文摘 | Eller C D Regelson M Merriman B | 2007 | Gene2007，390，12： | 1 |
| 18 | A Level Set Formulation of Eulerian Interface Capturing Methods for Incompressible Fluid Flows 显示文摘 | Hou T Y Merriman B | 1996 | J Comput Phys1996，124，： | 1 |
| 19 | A variation-al level set approach to multiphase motion 显示文摘 | Zhao H K Chan T Merriman B | 1996 | Journal of Computational Physics1996，127，1： | 1 |
| 20 | A PDE-based fast level set method 显示文摘 | Peng Danping Merriman B Osher Stanley | 1999 | Journal of Computational Physics1999，155，2： | 1 |
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