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| 1 | Preoperative immunonutrition in patients undergoing liver resection:A prospective randomized trial显示文摘BACKGROUND Preoperative supplementation with immunonutrients, including arginine and n-3 fatty acids, has been shown in a number of systematic reviews to reduce infectious complications in patients who have undergone gastrointestinal surgery. Limited information, however, is available on the benefits of nutritional supplementation enriched with arginine and n-3 fatty acids in patients undergoing liver resection.AIM To evaluate the effects of preoperative nutritional supplementation enriched with arginine and n-3 fatty acids on inflammatory and immunologic markers and clinical outcome in patients undergoing liver resection.METHODS Thirty-four patients undergoing liver resection were randomized to either five days of preoperative Impact? [1020 kcal/d, immunonutrition(IMN) group], or standard care [no supplementation, standard care(STD) group]. Nutritional status was measured at study entry by subjective global assessment(SGA).Functional assessments(grip strength, fatigue and performance status) were carried out at study entry, on the day prior to surgery, and on postoperative day(POD) 7 and 30. Inflammatory and immune markers were measured at study entry, on the day prior to surgery, and POD 1, 3, 5, 7, 10 and 30. Postoperative complications were recorded prospectively until POD30.RESULTS A total of 32 patients(17 IMN and 15 STD) were analysed. All except four patients were SGA class A. The plasma ratio of(eicosapentaenoic acid plus docosahexaenoic acid) to arachidonic acid was higher in IMN patients on the day prior to surgery and POD 1, 3, 5 and 7(P < 0.05). Plasma interleukin(IL)-6 concentrations were elevated in the IMN group(P = 0.017 for POD7). No treatment effect was detected for functional measures, immune response(white cell count and total lymphocytes) or markers of inflammation(C-reactive protein,tumour necrosis factor-α, IL-8, IL-10). There were 10 patients with infectious complications in the IMN group and 4 in the STD group(P = 0.087). Median hospital stay was 9(range 4–49) d in the IMN group and 8(3-34) d in the STD group(P = 0.476).CONCLUSION In well-nourished patients undergoing elective liver resection, this study failed to show any benefit of preoperative immunonutrition. | Kylie Russell Han-Guang Zhang Lyn K GillANDers Adam SJR Bartlett Helena L Fisk Philip C Calder Peter J Swan Lindsay D Plank | 2019 | World Journal of Hepatology2019，11，3： | 3 |
| 2 | Meeting report:a hard look at the state of enamel research显示文摘The Encouraging Novel Amelogenesis Models and Ex vivo cell Lines(ENAMEL) Development workshop was held on 23 June 2017 at the Bethesda headquarters of the National Institute of Dental and Craniofacial Research(NIDCR). Discussion topics included model organisms, stem cells/cell lines, and tissues/3 D cell culture/organoids. Scientists from a number of disciplines,representing institutions from across the United States, gathered to discuss advances in our understanding of enamel, as well as future directions for the field. | ophir d klein olivier duverger wendy shaw rodrigo s lacruz derk joester janet moradian-oldak megan k pugach j timothy wright sarah e millar ashok b kulkarni john d bartlett thomas gh diekwisch pamela den besten james p simmer | 2017 | International Journal of Oral Science2017，9，4： | 3 |
| 3 | Review and assessment of methane emissions from wetlands显示文摘 | Bartlett K B Harriss R C | 1993 | Chemosphere1993，26，： | 2 |
| 4 | Review and assessment of methane emissions form wetlands显示文摘 | Bartlett K B Harris R C | 1993 | Chemosl0here1993，26，： | 1 |
| 5 | Use of randomly amplified polymorphic DNA markers for the genetic analysis of relatedness and diversity in chickens and turkeys 显示文摘 | Smith E J Jones C P Bartlett J Nestor K E | 1996 | Poultry Sciences1996，75，2： | 1 |
| 6 | Recognizing faces with PCA and ICA显示文摘 | Draper B A Baek K Bartlett M S | 2003 | Computer Vision Image Understanding2003，91，1： | 1 |
| 7 | Relationships between HMG-CoA reductase inhibitors (statin) use and strength, balance and falls in older people 显示文摘 | Haerer W Delbaere K Bartlett H | 2010 | Intern Med2010，42，： | 1 |
| 8 | Popliteal artery-tibial plateau relationship before and after total knee replacement: a prospective ultrasound study显示文摘 | Eriksson K Bartlett J | 2010 | Knee Surg Sports Traumatol Arthrosc2010，18，7： | 1 |
| 9 | A pre-operative intervention for pain reduction, improved mobility and self-effieacy显示文摘 | Heye M L Foster L Bartlett M K | 2002 | Appl Nurs Res2002，15，3： | 1 |
| 10 | Growth and body composition of dairy calves fed milk replacers containing different amounts of protein at two feeding rates显示文摘 | Bartlett K S Mckeith F K Vandehaar M J | 2006 | J Anim Sci2006，84，： | 1 |
| 11 | Multiple biochemical effects in the pathogenesis of alcoholic fatty liver显示文摘 | Eaton S Record CO Bartlett K | 1997 | European Journal of Clinical Investigation1997，27，9： | 1 |
| 12 | Serum lep?tin is elevated in Saudi Arabian patients with metabolic syn?drome and coronary artey disease显示文摘 | Al-Daghri N Al-Rubean K Bartlett WA | 2003 | Diabet Med2003，20，： | 1 |
| 13 | Multiple biochemical effects in the pathogenesis of alcoholic fatty liver 显示文摘 | Eaton S Record C O Bartlett K | 1997 | Eur J Clin Invest1997，27，9： | 1 |
| 14 | Growth and body composition of dairy calves fed milk replacers containing different amounts of protein at two feeding rates 显示文摘 | Bartlett K S McKeith F K VandeHaar M J | 2006 | Journal of Animal Science2006，，84： | 1 |
| 15 | Robotic liver surgery显示文摘 | Idrees K Bartlett DL | 2010 | Surg Clin North Am2010，90，4： | 1 |
| 16 | Anti-CD30 antibodies for Hodgkin lymphoma显示文摘 | Foyil K V Bartlett N L | 2010 | Curr Hematol Malig Rep2010，5，3： | 1 |
| 17 | High pressure influences on gene and protein expression显示文摘 | BARTLETT D H KATO C HORIKOSHI K | 1995 | Res Microbiol1995，146，： | 1 |
| 18 | Recognizing faces with PCA and ICA显示文摘 | Draper B Baek K Bartlett M S | 2003 | Computer Vision and Image Understanding(Special Issue on Face Recognition)2003，91，12： | 1 |
| 19 | Review assessment of methane emissions from wetlands 显示文摘 | Bartlett K B Harriss R C | 1993 | Chemosphere1993，26，14： | 1 |
| 20 | Methane flux from Minnesota peatlands显示文摘 | Crill P M Bartlett K B Sebacher D I | 1988 | Global Biogeochemistry Cycles1988，2，： | 1 |
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