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| 1 | Non-invasive means of measuring hepatic fat content显示文摘Hepatic steatosis affects 20% to 30% of the general adult population in the western world. Currently, the technique of choice for determining hepatic fat deposition and the stage of fibrosis is liver biopsy. However, it is an invasive procedure and its use is limited, particularly in children. It may also be subject to sampling error. Non-invasive techniques such as ultrasound, computerised tomography (CT), magnetic resonance imaging (MRI) and proton magnetic resonance spectroscopy (1H MRS) can detect hepatic steatosis, but currently cannot distinguish between simple steatosis and steatohepatitis, or stage the degree of fibrosis accurately. Ultrasound is widely used to detect hepatic steatosis, but its sensitivity is reduced in the morbidly obese and also in those with small amounts of fatty infiltration. It has been used to grade hepatic fat content, but this is subjective. CT can detect hepatic steatosis, but exposes subjects to ionising radiation, thus limiting its use in longitudinal studies and in children. Recently, magnetic resonance (MR) techniques using chemical shift imaging have provided a quantitative assessment of the degree of hepatic fatty infiltration, which correlates well with liver biopsy results in the same patients. Similarly, in vivo 1H MRS is a fast, safe, non-invasive method forthe quantification of intrahepatocellular lipid (IHCL) levels. Both techniques will be useful tools in future longitudinal clinical studies, either in examining the natural history of conditions causing hepatic steatosis (e.g. non-alcoholic fatty liver disease), or in testing new treatments for these conditions. | Sanjeev R Mehta E Louise Thomas Jimmy D Bell Desmond G Johnston Simon D Taylor-Robinson | 2008 | World Journal of Gastroenterology2008，14，22： | 21 |
| 2 | Effects of purified dies containing different combinations of arachidonic and docosahexaenoic acid on survival, growth and fatty acid composition of juvenile turbot (Scophthalmus maximus) 显示文摘 | Castell J D Bell J G Tocher D R | 1994 | Aquaculture1994，1，： | 2 |
| 3 | Abundance and partitioning of OH in a hlgh-pressure magmatic system: Megacrysts from the Monastery kimberlite, South Africa显示文摘 | Bell D B Rossman G R Moore R O | 2004 | J Petrol2004，45，： | 1 |
| 4 | A physicochemical study of the aging of colloidal sillica gels used in zeolite Y synthesis显示文摘 | Ginter D M Went G T Bell A T | 1992 | Zeolites1992，12，： | 1 |
| 5 | Effects of essential fatty acid-deficient diets on growth, mortality, tissue histopathology and fatty acid compositions in juvenile turbot ( Scophthalmus maximus) 显示文摘 | BELL J G TOCHER D R FARNDALE B M | 1999 | Fish Physiol Biochem1999，20，3： | 1 |
| 6 | Effects of purified diets containing different combinations of arachidonic and docosahexaenoic acid on survival,growth and fatty acid composition of juvenile turbot (Scophthalmus maximus )显示文摘 | Castell J D Bell J G Tocher D R | 1994 | Aquaculture1994，128，： | 1 |
| 7 | Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternative spliced exons显示文摘 | Screaton G R Bell M V Jackson D G | 1992 | Proc Natl Acad Sci USA1992，89，12： | 1 |
| 8 | Price Competition under Stockpiling and Flexible Con- sumption显示文摘 | BELL D R IYER G PADMANABHAN V | 2002 | Journal of Marketing Research2002，39，8： | 1 |
| 9 | Terminating eukaryote translation: domainl of release factor eRF1 functions in stop codon recognition显示文摘 | Bertram G Bell H A Ritchie D W | 2000 | RNA2000，，6： | 1 |
| 10 | Development and application of molecular marker linkage maps in woody fruit crops显示文摘 | N F Weeden M Hemmatt D M Lawson M Lodhi R L Bell A G Manganaris B I Reischs S K Brown G N Ye | 1994 | Euphytica1994，77，12： | 1 |
| 11 | Attacker-defender models and road network vulnerability 显示文摘 | Bell M G H Kanturska U Schmocker J D | 2008 | Philosophical Transactions of the Royal Society A-Mathematical Physical and Engineering Sciences2008，366，1872： | 1 |
| 12 | OptorSim:A grid simulator for studying dynamic data replication strategy显示文摘 | Bell W H Cameron D G Capozza L | 2003 | International Journal of High Performance Computing Applications2003，17，4： | 1 |
| 13 | A geotechnical overview of Katse Dam and Transfer Tunnel,Lesotho,with a note on basalt durability显示文摘 | Bell F G Haskins D R 1997 | 1997 | Engineering Geology1997，46，2： | 1 |
| 14 | Hydroxide in pyroxene: Variations in the natural environment显示文摘 | Skogby H Bell D R Rossman G R | 1990 | Am Mineral1990，75，： | 1 |
| 15 | Requirement criteria for essential fatty acids显示文摘 | Sargent J R Bell J G Bell M V Henderson R J Tocher D R | 1995 | J Appl Ichthyol1995，11，： | 1 |
| 16 | Soil acidification and the carbon cycle in a cropping soil of north- eastern Victoria显示文摘 | Slattery W J Edwards D G Bell L C | 1998 | Australian Journal of Soil Research1998，36，2： | 1 |
| 17 | NASA World Wind: Opensource GIS for mission operations显示文摘 | Bell D G Kuehnel F | 2007 | Aerospace Conference2007，，： | 1 |
| 18 | Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons显示文摘 | Screaton G R Bell M V Jackson D G | 1992 | Proc Natl Acad Sic USA1992，89，12： | 1 |
| 19 | Lipid nutrition of marine fish during early development:current status and future directions显示文摘 | Sargent J R McEvoy L A Estevez A Bell J G Bell M V Henderson R J Tocher D R | 1999 | Aquaculture1999，179，： | 1 |
| 20 | OptorSim - A Grid Simulator for Studying Dynamic Data Replication Strategies 显示文摘 | W H Bell D G Cameron L Capozza A P Millar K Stockinger and F Zini | 2003 | International Journal of High Performance Computing Applications2003，17，4： | 1 |
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