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| 1 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012，45，5： | 22 |
| 2 | Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density显示文摘 | W.S Simonet D.L Lacey C.R Dunstan M Kelley M.-S Chang R Lüthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.-L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van | 1997 | Cell1997，，2： | 6 |
| 3 | Precision atomic gravimeter based on Bragg diffraction显示文摘 | P A Altin M T Johnsson V Negnevitsky G R Dennis R P Anderson J E Debs S S Szigeti K S Hardman S Bennetts G D McDonald L D Turner J D Close N P Robins | 2013 | New Journal of Physics2013，，2： | 2 |
| 4 | Melting magnesium under air/SF~ protective atmospheres 显示文摘 | Couling S L Bennett F C Leontis T E | 1997 | Light Metal Age1997，，1： | 1 |
| 5 | Homocysteine and Coronary Heart Disease:Meta-analysis of MTHFR Case Contorl Studies,Avoiding Publication Bias显示文摘 | Clakre E Bennett DA Parish S | 2012 | PLoS Med2012，9，10： | 1 |
| 6 | Education in cancer pain manage-ment 显示文摘 | MichaelI Bennett Kate Flemming S Jos e Closs | 2011 | Curt Opin Support Palliat Care2011，5，： | 1 |
| 7 | In vivo insulin sensitivity in the rat determined by euglycemic clamp显示文摘 | KRAEGEN E W JAMES D E BENNETT S P | 1983 | Am J Physiol1983，245，1： | 1 |
| 8 | Vertical jumpcoordination:fatigue effects显示文摘 | RODACKI A L FOWLER N E BENNETT S J | 2002 | Med Sci Sports Exe2002，34，1： | 1 |
| 9 | A locus for paroxysmal kinesigenic dyskinesia maps to human chromosome 16显示文摘 | Bennett L B Roach E S Bowcock A M | 2000 | Neurology2000，54，1： | 1 |
| 10 | 2B4(CD244) and CS1: novel members of the CD2 subset of the immunoglobulin superfamily molecules expressed on natural killer cells and other leukocytes 显示文摘 | Boles K S Stepp S E Bennett M | 2001 | Immunol Rev2001，181，： | 1 |
| 11 | Regulation of Wnt signaling duringadipogenesis显示文摘 | Bennett C N Ross S E Longo K A | 2002 | Biol Chem2002，277，31： | 1 |
| 12 | Laid off,but still loyal:The influence of perceived justice and organizational support显示文摘 | Naumann S E Bennett N Bies R J | 1998 | International Journal of Conflict Management1998，9，4： | 1 |
| 13 | Analysis of cDNAfor human erythrocyte ankyrin indicates a repeated structure with homology to tissue-differentiation and cell-cycle control pro- teins显示文摘 | LUX S E JOHNK M BENNETT V | 1990 | Nature1990，344，6261： | 1 |
| 14 | The stability of supply chains显示文摘 | Riddalls C E Bennett S | 2002 | Inter- national Journal of Production Research2002，40，2： | 1 |
| 15 | A Case for Procedural Justice Cli- mate:Development and Test of a Multilevel Model 显示文摘 | Naumann S E Bennett N | 2000 | Acad- emy of Management Journal2000，43，5： | 1 |
| 16 | Modelling the dynamics of supply chains显示文摘 | Riddalls C E Bennett S Tipi N S | 2000 | International Journal of Systems Science2000，31，8： | 1 |
| 17 | Antecedents and sex/gender differences in youth suicidal behavior显示文摘Suicide is the second leading cause of death in youth globally; however, there is uncertainty about how best to intervene. Suicide rates are typically higher in males than females, while the converse is true for suicide attempts. We review this 'gender paradox' in youth, and in particular, the age-dependency of these sex/gender differences and the developmental mechanisms that may explain them. Epidemiologic, genetic,neurodevelopmental and psychopathological research have identified suicidal behaviour risks arising from genetic vulnerabilities and sex/gender differences in early adverse environments, neurodevelopment, mental disorder and their complex interconnections. Further, evolving sex-/gender-defined social expectations and norms have been thought to influence suicide risk. In particular, how youth perceive and cope with threats and losses(including conforming to others' or one's own expectations of sex/gender identity) and adapt to pain(through substance use and helpseeking behaviours). Taken together, considering brain plasticity over the lifespan, these proposed antecedents to youth suicide highlight the importance of interventions that alter early environment(s)(e.g., childhood maltreatment) and/or one's ability to adapt to them. Further, such interventions may have more enduring protective effects, for the individual and for future generations, if implemented in youth. | Anne E Rhodes Michael H Boyle Jeffrey A Bridge Mark Sinyor Paul S Links Lil Tonmyr Robin Skinner Jennifer M Bethell Corine Carlisle Sarah Goodday Travis Salway Hottes Amanda Newton Kathryn Bennett Purnima Sundar Amy H Cheung Peter Szatmari | 2014 | World Journal of Psychiatry2014，4，4： | 1 |
| 18 | Substitution of alanine for serine 250 in the murine fatty acid transport protein inhibits long chain fatty acid transport显示文摘 | STUHLSATZ K S M BENNETT N E SCHAFFERJ E | 1998 | Journal of Biology Chemistry1998，273，28： | 1 |
| 19 | Vitamin E and donepezil for the treatment of mild cognitive impairment显示文摘 | Petersen RC Thomas RG Grundman M Bennett D Doody R Ferris S Galasko D Jin S Kaye J Levey A Pfeiffer E Sano M van Dyck CH Thal LJ Alzheimer's Disease Cooperative Study Group | | 0，，23： | 1 |
| 20 | An investigation of the reliability of Rapid Upper Limb Assessment ( RULA ) as a method of assessment of children's computing posture 显示文摘 | Dockrell S O'Grady E Bennett K | 2012 | Appl Ergon2012，43，3： | 1 |
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