|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | On the mechanical behavior of the human biliary system显示文摘This paper reviews the progress made in understanding the mechanical behaviour of the biliary system. Gallstones and diseases of the biliary tract affect more than 10% of the adult population. The complications of gallstones, i.e. acute pancreatitis and obstructive jandice, can be lethal, and patients with acalculous gallbladder pain often pose diagnostic difficulties and undergo repeated ultrasound scans and oral cholecystograms. Moreover, surgery to remove the gallbladder in these patients, in an attempt to relieve the symptoms, gives variable results. Extensive research has been carried out to understand the physiological and pathological functions of the biliary system, but the mechanism of the pathogenesis of gallstones and pain production still remain poorly understood. It is believed that the mechanical factors play an essential role in the mechanisms of the gallstone formation and biliary diseases. However, despite the extensive literature in clinical studies, only limited work has been carried out to study the biliary system from the mechanical point of view. In this paper, we discuss the state of art knowledge of the fluid dynamics of bile flow in the biliary tract, the solid mechanics of the gallbladder and bile ducts, recent mathematical and numerical modelling of the system, and finally the future challenges in the area. | Xiaoyu Luo Wenguang Li Nigel Bird Swee Boon Chin NA Hill Alan G Johnson | 2007 | World Journal of Gastroenterology2007，13，9： | 9 |
| 2 | Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density显示文摘 | W.S Simonet D.L Lacey C.R Dunstan M Kelley M.-S Chang R Lüthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.-L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van | 1997 | Cell1997，，2： | 6 |
| 3 | Fecal lactoferrin accurately reflects mucosal inflammation in inflammatory bowel disease显示文摘BACKGROUND Studies have demonstrated a potential role for fecal biomarkers such as fecal calprotectin(FC)and fecal lactoferrin(FL)in monitoring inflammatory bowel diseases(IBD)-Crohn's disease(CD)and ulcerative colitis(UC).However,their correlation to endoscopic scores,disease severity and affected intestinal surface has not been extensively investigated.AIM To correlate FL,and for comparison white blood cell(WBC)and C-reactive protein(CRP),with endoscopic scores,disease extent and location in CD and UC.METHODS Retrospective analysis in 188 patients who had FL,CRP and WBC determined within 30 d of endoscopy.Disease location,disease extent(number of intestinal segments involved),disease severity(determined by endoscopic scores),timing of FL testing in relation to colonoscopy,as well as the use of effective fast acting medications(steroids and biologics)between colonoscopy and FL measurement,were recorded.RESULTS In 131 CD and 57 UC patients,both CRP and FL-but not WBC-distinguished disease severity(inactive,mild,moderate,severe).In patients receiving fastacting(steroids or biologics)treatment in between FL and colonoscopy,FL showed a higher correlation to endoscopic scores when tested before vs after the procedure(r=0.596,P<0.001,vs r=0.285,P=0.15 for the Simple Endoscopic Score for CD;and r=0.402,P=0.01 vs r=0.054 P=0.84 for Disease Activity Index).Finally,FL was significantly correlated with the diseased mucosal surface(colon-ileocolon>small bowel)and the number of inflamed colon segments.CONCLUSION FL and CRP separated disease severity categories with FL showing lower discriminating P-values.FL showed a close correlation with the involved mucosal surface and with disease extent and was more closely correlated to endoscopy when determined before the procedure–this indicating that inflammatory activity changes associated with therapy might be rapidly reflected by FL levels.FL can accurately and timely characterize intestinal inflammation in IBD. | Marrieth G Rubio Kofi Amo-Mensah James M Gray Vu Q Nguyen Sam Nakat Douglas Grider Kim Love James H Boone Dario Sorrentino | 2019 | World Journal of Gastrointestinal Pathophysiology2019，10，5： | 4 |
| 4 | Hydrodesulfurization studies with a single -layer molybdenum disulfite catalyst 显示文摘 | Boone W P Ekerdt J G | 2000 | Journal of Catalysis2000，193，： | 1 |
| 5 | Proteomic analysis of the Arabidopsis nucleolus suggests novel nucleolar functions显示文摘 | Pendle A F Clark G P Boon R | 2005 | Mol Biol Cell2005，16，： | 1 |
| 6 | River Conservation and Management显示文摘 | P J Boon P Calow G E Petts | 1992 | John Wiley & Sons1992，，： | 1 |
| 7 | Is this patient dead,vegetative,or severely neurologically impaired? Assessing outcome for comatose survivors of cardiac arrest显示文摘 | Booth CM Boone RH Tomlinson G | | 0，，07： | 1 |
| 8 | Synthe- sis of LD-Hepp and Kdo containing di- and tetrasac- charide derivatives of Neisseriu meningitidis inner-core region via iodonium ion promoted glycosidations 显示文摘 | Boons G J Van D F L Vander K P M | 1992 | Tetrahedron1992，48，5： | 1 |
| 9 | APRIL and TALL1 and receptors BCMA and TACI:system for regulation humoral activity显示文摘 | YU G BOONE T DELANEY J | 2000 | Nat Immunol2000，1，3： | 1 |
| 10 | Direct temperature resolved HRMS of fire-retarded polymers by in-Source PyMS on an external ion source fourier transform ion cyclotron resonance mass spectrometer显示文摘 | Heeren R M A De Koster C G Boon J J | 1995 | Analytical Chemistry1995，67，21： | 1 |
| 11 | Speticity in sewers:causes,consequences and containment显示文摘 | BOON A G | 1995 | Water Sci Technol1995，31，7： | 1 |
| 12 | Oxidation, Kinetics of Zinc Sulphide with Thiobacillus ferrooxidans 显示文摘 | Boon M Snider M Hansford G S | 1998 | Hydromrtallurgy1998，48，2： | 1 |
| 13 | Targets for molecular therapy in esophageal cell carcinoma:an immunohistochemical analysis显示文摘 | Boone J van Hillegersberg R Offerhaus G J | | 0，，06： | 1 |
| 14 | Microwave stabilization versus chemical fixation:A morphometric study in glycolmethacrylate - and paraffin-embedded tissue显示文摘 | Van de Kant H J De Booij D G Boon M E | 1990 | Histochem J1990，22，67： | 1 |
| 15 | The dynamics of interpersonal trust:Resolving uncertainty in the face of risk显示文摘 | Boon S D Holmes J G | 1991 | Cooperation and prosocial behavior1991，，： | 1 |
| 16 | City structure, obesity, and environmental justice: An integrated analysis of physical and social barriers to walkable streets and park access 显示文摘 | CuRs B B Darby K J Boone C G Brewis A | 2009 | Social Science & Medicine2009，69，9： | 1 |
| 17 | Effect of plant growth on copper solubility and speciation in soil solution samples显示文摘 | Bouwman L A Boon G T | 1999 | Environmental Pollution1999，106，： | 1 |
| 18 | Mutation detection by electrocatalysis at DNA-modified electrodes显示文摘 | Ceres D M Drummond T G | 2000 | Nature Biotechnology2000，18，10： | 1 |
| 19 | Commonalities and Contradictions in HRM and Performance Research 显示文摘 | Boselie P Dietz G Boon C | 2005 | Human Resource Management Journal2005，15，3： | 1 |
| 20 | The impact of adhesions on operations and postoperative recov- ery in colon cancer surgery显示文摘 | Ramzi Amri Itannah C den Boon Liliana G Bordeianou | 2013 | Am J Surg2013，206，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员