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| 1 | Associations of sense of coherence with psychological distress and quality of life in inflammatory bowel disease显示文摘AIM:To investigate the relationship between sense of coherence,psychological distress and health related quality of life in inflammatory bowel disease(IBD).METHODS:This cross-sectional study enrolled a consecutive sample of 147 IBD(aged 45.1 ± 14.1 years; 57.1% female) patients recruited from a tertiary gastroenterology service.Sixty-four participants met diagnostic criteria for Crohn's disease,while eightythree patients had ulcerative colitis.Socio-demographic data(education,age,race,gender,gross monthly income and marital status),disease-related variables(illness activity,relapse rate in past 2 years,history of surgery and time since diagnosis),sense of coherence(Antonovsky's SOC scale),psychological distress symptoms(Hospital Anxiety and Depression Scale) and health-related quality of life(HRQo L; WHOQOLBref) were assessed.Hierarchical multiple regression analyses were performed to identify factors that are independently associated with psychological distress and HRQo L in patients with IBD and to provide indications for possible moderating or mediating effects.In addition,formal moderation and mediation analyses(Sobel tests) were performed to confirm potential moderators/mediators of the relationship between SOC,psychological distress symptoms and HRQoL.RESULTS:Lower SOC scores(std beta=-0.504; P < 0.001),female gender(std beta = 0.176; P = 0.021) and White race(std beta = 0.164; P = 0.033) were independently associated with higher levels of depressive symptoms,while lower levels of SOC(std beta =-0.438; P < 0.001) and higher relapse rate(std beta = 0.161; P = 0.033) were independently associated with more severe anxiety symptoms.A significant interaction between time since diagnosis and SOC was found with regard to the severity of depressive or anxiety symptoms,as the interaction term(time since diagnosis X SOC) had beta coefficients of-0.191(P = 0.009) and-0.172(P = 0.026),respectively.Lower levels of anxiety symptoms(std beta =-0.369; P < 0.001),higher levels of SOC(std beta = 0.231; P = 0.016) and non-White race(std beta =-0.229; P = 0.006),i.e.,mixed-race,which represented the reference category,were independently associated with higher levels of overall HRQoL.Anxiety symptoms were the most potent independent correlate of most aspects of HRQoL.In addition,anxiety mediated the association between SOC and satisfaction with health,as well as its relationship with physical,mental,and social relations HRQo L.Depressive symptoms also mediated the association between SOC and mental HRQoL.CONCLUSION:Our data indicated that SOC is an important construct,as it influences psychological distress and has significant albeit indirect effects on several HRQoL domains in IBD. | Thiago H Freitas Elias Andreoulakis Gilberto S Alves Hesley LL Miranda Lúcia LBC Braga Thomas Hyphantis André F Carvalho | 2015 | World Journal of Gastroenterology2015，21，21： | 10 |
| 2 | Relationship be- tween lipids and bone mass in tow cohorts of healthy women and men显示文摘 | Adami S Braga V Zamboni M | 2004 | Calcif Tissue Int2004，74，： | 1 |
| 3 | Effect of the inoculation level of Lactobacillus acidophilus in probiotic cheese on the physicochemical features and sensory performance compared with commercial cheeses显示文摘 | GOMES A A BRAGA S P CRUZ A G | 2011 | Journal of Dairy Science2011，94，： | 1 |
| 4 | Inflammatory Myofibroblastic Tumor of the Hepatobiliary System:Report of MR Imaging Appearance in Four Patients显示文摘 | Venkataraman S Semelka RC Braga L | | 0，，3： | 1 |
| 5 | Site-specific effects of strength training on bone structure and geometry of ultra distal radius in postmenopausal women显示文摘 | Asami S Gatti D Braga V | 1999 | J Bone Miner Res1999，14，1： | 1 |
| 6 | Urinary 11-dehydro thromboxane B 2 levels in type 2 diabetic patients before and during aspirin intake显示文摘 | Lillian Harboe Gon?alves Luci Maria Sant'Ana Dusse Ana Paula Fernandes Karina Braga Gomes Mirelle Oliveira Sóter Michelle Teodoro Alves Kathryna Fontana Rodrigues Fernanda Rocha Freitas Flavia Komatsuzaki Marinez Oliveira Sousa Adriana Aparecida Bosco Gér | 2011 | Clinica Chimica Acta2011，，15： | 1 |
| 7 | Fate of steroid estrogens in Australian inland and coastal wastewater treatment plants 显示文摘 | BRAGA O SMYTHE G A FEITZ A J S | 2005 | Environ Sci Technol2005，39，9： | 1 |
| 8 | Structural effects of WO3 incorporation on USY zeolite and applica- tion to free fatty acids esterification显示文摘 | Costa A A Braga P R S Macedo J L | 2012 | Microporous and Mesoporous Materials2012，147，1： | 1 |
| 9 | Obstruction of pipelines due to paraffin deposition during the flow of crude oils显示文摘 | Ribeiro F S Mendes P R S Braga S L | 1997 | International Journal of Heat Mass Transfer1997，18，1： | 1 |
| 10 | Profile of impurities in polycrystalline silicon samples purified in an electron beam melt ing furnace显示文摘 | PIRES J C S BRAGA A F B MEI P R | 2003 | Solar Energy Materials &Solar Cells2003，79，3： | 1 |
| 11 | Immobilization of Fe, Mn and Co tetraphenylporphyrin complexes in MCM-41 and their catalytic activity in cyclohexene oxidation reaction by hydrogen peroxide 显示文摘 | COSTA A A GHESTI G F MACEDO J L BRAGA V S SANTOS M M DIAS J A DIAS S C L | 2008 | J Mol Catal A: Chem2008，282，： | 1 |
| 12 | Sleep apnoea in ischaemic heart disease: differences between acute and chronic coronary syndromes 显示文摘 | Moruzzi P Sarzi -Braga S Rossi M | 1999 | Heart1999，82，3： | 1 |
| 13 | Serum humanepididymis protein 4 vs carbohydrate antigen 125 for ovariancancer diagnosis显示文摘 | Ferrar S Braga F Lanzoni M | 2013 | Clin Pathol2013，66，4： | 1 |
| 14 | Inflammatory myofibroblastic tumor of the hepatobiliary system: report of MR imaging appearance in four patients 显示文摘 | Venkataraman S Semelka RC Braga L | 2003 | Radiology2003，227，3： | 1 |
| 15 | The purifica- tion of metallurgical grade silicon by electron beam rnelting显示文摘 | PIRES J C S OTUBO J BRAGA A F B | 2005 | Journal of Materials Processing Technology2005，169，1： | 1 |
| 16 | Iwvitro sensitiv ity of infective larvae of Oesophagostomum species to nemato phagous fungi显示文摘 | Ferreira S R Araujo J V Braga F R | 2012 | Vet Scan2012，7，： | 1 |
| 17 | New Processes for the Production of Solar-grade Polycrystalline Silicon:A Review显示文摘 | Braga A F B Moreira S P Zampieri P R | | 0，，： | 1 |
| 18 | Mitracarpus frigidus aerial parts exhibited potent antimicrobial, antileishmanial, and antioxidant effects显示文摘 | Fabri R L Nogueira M S Braga F G | 2009 | Bioresour Technol2009，100，1： | 1 |
| 19 | Steroid estrogens in ocean sediments显示文摘 | BRAGA O S G SHAFER A I FEITZ A J | 2005 | Chemosphere2005，61，6： | 1 |
| 20 | New processes for the production of solar-grade polycrystalline silicon: A review显示文摘 | Braga A F B Moreira S P Zampieri P R | 2008 | Solar Energy Materials and Solar Cells2008，92，4： | 1 |
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