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| 1 | Sperm retrieval success and testicular histopathology in idiopathic nonobstructive azoospermia显示文摘Prior studies have investigated sperm retrieval rates in men with non obstructive azoospermia(NOA)secondary to specific etiologies,yet most cases of NOA are idiopathic.We compared sperm retrieval rates and testicular histopathology in idiopathic NOA(iNOA)and nonidiopathic NOA(niNOA).We performed a retrospective review of men with NOA who underwent microdissection testicular sperm extraction(microTESE)between 2000 and 2016.Men with no history of malignancy or cryptorchidism and negative genetic evaluation were considered idiopathic.Multivariable regression determined the association between idiopathic etiology and primary outcomes of sperm retrieval and active spermatogenesis on histopathology.Among 224 men,86(38.4%)were idiopathic,75(33.5%)were nonidiopathic,and 63(28.1%)did not undergo genetic testing.Median age and serum testosterone were higher among iNOA or no testing versus niNOA.Median follicle-stimulating hormone(FSH)was lower among iNOA or no testing versus niNOA.A higher proportion of iNOA or no testing versus niNOA had a clinical varicocele.Sperm retrieval rates were similar between iNOA,niNOA,and no testing(41.8%vs 48.0%vs 55.6%,respectively;P=0.255).Active spermatogenesis was seen in a higher proportion of iNOA or no testing versus niNOA(31.4%and 27.0%vs 16.0%,P=0.073).On multivariable analysis,iNOA was not associated with sperm retrieval or spermatogenesis(P=0.430 and P=0.078,respectively).Rates of sperm retrieval and spermatogenesis on testis pathology were similar in men with iNOA and niNOA.These data will be useful to clinicians in preoperative counseling for men with NOA and negative genetic evaluation. | Arighno Das Joshua A Halpern Annie L Darves-Bornoz Mehul Patel James Wren Mary Kate Keeter Robert E Brannigan | 2020 | Asian Journal of Andrology2020，22，6： | 3 |
| 2 | Insertion of an extra amino acid is the main cause of the low affinity of penicillin-binding protein 2 in penicillin-resistant strains of Neisseria gonorrhoeae 显示文摘 | Brannigan JA Tirodimos IA Zhang QY | 1990 | Mol Microbiol1990，4，： | 1 |
| 3 | Association of hemospermia with prostate cancer显示文摘 | Han M Brannigan RE Antenor JA | 2004 | J Urol2004，172，61： | 1 |
| 4 | Blood flow patterns in focal liver lesions at microbuhble - enhanced US 显示文摘 | Brannigan M Bums PN Wilson SR | 2004 | Radiographics2004，24，12： | 1 |
| 5 | Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small cell lung cancer to gefitinib 显示文摘 | Lynch TJ Bell DW Sordella R Gurubhagavatula S Okimoto RA Brannigan BW | 2004 | N Engl J Med2004，350，21： | 1 |
| 6 | Comparison of tunica albuginea substitutes for the treatment of Peyronie's disease显示文摘 | Brannigan RE Kim ED Oyasu R | 1998 | J Urol1998，159，3： | 1 |
| 7 | Neutrophil apoptosis is delayed in patients with inflammatory bowel disease显示文摘 | BRANNIGAN AE O'CONNELL PR HURLEY H | 2000 | Shock2000，13，5： | 1 |
| 8 | Blood flow pat- terns in focal liver lesions at microbubble-enhanced US 显示文摘 | Brannigan M Bums P N Wilson S R | 2004 | Radiographics2004，24，4： | 1 |
| 9 | The crystal structures of macrophage migration inhibitory factor from Plasmodiam falciparum and Plasmodium berghei 显示文摘 | Dobson SE Augustijn KD Brannigan JA | 2009 | Protein Sci2009，18，12： | 1 |
| 10 | Ileal pouch-anal anastomosis 显示文摘 | McGuire BB Brannigan AE O'Connell PR | 2007 | Br J Surg2007，94，7： | 1 |
| 11 | Aprotein catalytic framework with an N-terminal nucleophile is capable of self-activation 显示文摘 | Brannigan JA Dodson G Duggleby HJ Moody PCE Smith JL Tomchick DR Murzin AG | 1995 | Nature1995，378，6557： | 1 |
| 12 | Sperm DNA dam- age evaluation techniques 显示文摘 | Dugum M Sandlow JI Brannigan RE | 2011 | Androl2011，32，3： | 1 |
| 13 | The T790M 'gatekeeper' mutation in EGFR mediates resistance to low concentrations of an irreversible EGFR inhibitor显示文摘 | Godin-Heymann N Ulkus L Brannigan BW | | 0，，04： | 1 |
| 14 | Increased adhesion molecule expression in serosal fibroblasts isolated from patients with inflammatory bowel disease is secondary to inflammation显示文摘 | Brannigan A Watson W Beddy D | 2002 | Ann Surg2002，235，4： | 1 |
| 15 | Blood flow patterns in focal liver lesions at microbubble-enhanced US 显示文摘 | Brannigan M Burns PN Wilson SR | 2004 | Radio- graphics2004，24，4： | 1 |
| 16 | Increased adhesion molecule expression in serosal fibroblasts isolated from patients with inflammatory bowel disease is secondary to inflammation显示文摘 | Brannigan AE Watson RW Beddy D | 2002 | Ann Surg2002，235，4： | 1 |
| 17 | Blood flow patterns in focal liver lesions at microbubble-enhanced US显示文摘 | Brannigan M Burns P N Wilson S R | 2004 | Radiographies2004，24，4： | 1 |
| 18 | Blood flowpatterns in focal liver lesions at microbubble-enhanced US显示文摘 | Brannigan M Burns PN Wilson SR | | 0，，： | 1 |
| 19 | Ileal pouch anal anastomosis显示文摘 | McGuire BB Brannigan AE O'Connell PR | 2007 | Br J Surg2007，94，7： | 1 |
| 20 | A critical analysis of the reported association between vasectomy and frontotemporal dementia显示文摘 | Tobias S K6hler Jeremy T Choy Anees A Fazili Joel F Koenig Robert E Brannigan | 2012 | Asian Journal of Andrology2012，14，6： | 1 |
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