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| 1 | Functions of NKG2D in CD8^(+) T cells: an opportunity for immunotherapy显示文摘Natural killer group 2 member D(NKG2D)is a type II transmembrane receptor.NKG2D is present on NK cells in both mice and humans,whereas it is constitutively expressed on CD8+T cells in humans but only expressed upon T-cell activation in mice.NKG2D is a promiscuous receptor that recognizes stress-induced surface ligands.In NK cells,NKG2D signaling is sufficient to unleash the killing response;in CD8+T cells,this requires concurrent activation of the T-cell receptor(TCR).In this case,the function of NKG2D is to authenticate the recognition of a stressed target and enhance TCR signaling.CD28 has been established as an archetype provider of costimulation during T-cell priming.It has become apparent,however,that signals from other costimulatory receptors,such as NKG2D,are required for optimal T-cell function outside the priming phase.This review will focus on the similarities and differences between NKG2D and CD28;less well-described characteristics of NKG2D,such as the potential role of NKG2D in CD8+T-cell memory formation,cancer immunity and autoimmunity;and the opportunities for targeting NKG2D in immunotherapy. | Kushal Prajapati Cynthia Perez Lourdes Beatriz Plaza Rojas Brianna Burke Jose A Guevara-Patino | 2018 | Cellular & Molecular Immunology2018，15，5： | 7 |
| 2 | Coronary plaque erosion without rupture into a lipid core: a frequent cause of coronary thrombosis in sudden coronary death显示文摘 | Farb A Burke AP Tang AL | 1996 | Circulation1996，93，： | 3 |
| 3 | Pathology of the unstable plaqueeta显示文摘 | Virmani R Burke AP Farb A etal | 2002 | Prog Cardiovasc Dis2002，44，： | 1 |
| 4 | A note on measuring parallelism in concurrent engineering显示文摘 | BURKE R J GRAVES R | 2000 | International Journal of Production Research2000，38，8： | 1 |
| 5 | Daily meatal care for prevention of catheter-associated bacteriuria:results using frequent applications of polyantibiotic cream显示文摘 | Classen D C Larsen R A Burke J P | 1991 | Infect Control Hosp Epidemiol1991，12，3： | 1 |
| 6 | Elevated C - reactive protein values and at herosclerosis in sudden coronary death association with different pat hologies 显示文摘 | BURKE A P TRACY R P MALCOM G T | 2001 | Circulation2001，105，： | 1 |
| 7 | Pathology of the vulnerable plaque显示文摘 | Virmani R Burke AP Farb A | 2006 | J Am Coil Cardiol2006，47，8： | 1 |
| 8 | Morphollgie finding of coronary atherosclerotic plaques in diabetics: a postern study 显示文摘 | Burke AP Kolodgie FD Zieske A | 2004 | Arterioseler Thromb Vase Biol2004，24，： | 1 |
| 9 | Grb2 signaling in cell motility and cancer显示文摘 | Giubellino A Burke T R Jr Bottaro D P | 2008 | Expert Opin Ther Targets2008，12，8： | 1 |
| 10 | Reducing temper embrittle by lanthanide additions 显示文摘 | Garcia C I Ratz G A Burke M G | 1985 | Journal of Metals1985，27，9： | 1 |
| 11 | Relative timing of rifting and volcanism on Earth and its tectonic implications显示文摘 | Sengor A M C Burke K | 1978 | Geophysical Research Letters1978，5，： | 1 |
| 12 | Evidence for a dose-response relationship between occupational noise and blood pressure显示文摘 | Talbott EO Gibson LB Burks A | 1999 | Arch Environ Health1999，54，： | 1 |
| 13 | Using GC-MS/ Combustion/IRMS to determine the^13 C/^12 C ratios of individual hydrocarbons produced from the combustion of biomass materials--application to biomass burning 显示文摘 | O'Malley V P Burke R A Schlotzhauer W S | 1997 | Organic Geochemistry1997，27，78： | 1 |
| 14 | The Impact d Cross- training on Team Effectiveness 显示文摘 | Marks M A Sabella M J Burke C S Zaccaro S J | 2002 | Jour- ruff tff Applied Psychology2002，83，： | 1 |
| 15 | The ripple effect: Biofuels, food security, and the environment显示文摘 | Naylor R L Liska A J Burke M B | 2007 | Environment: Science and Policy for Sustainable Development2007，49，9： | 1 |
| 16 | Hypoallergenicity of rice bran protein 显示文摘 | Helm R M Burks A W | 1996 | Cereal Foods World1996，，41： | 1 |
| 17 | The effects of ω3 fatty acids and coenzyme Q10 on blood pressure and heart rate in chronic kidney disease: a randomized controlled trial显示文摘 | Trevor A Mori Valerie Burke Ian B Puddey Ashley B Irish Christine A Cowpland Lawrence J Beilin Gursharan K Dogra Gerald F Watts | 2009 | Journal of Hypertension2009，，9： | 1 |
| 18 | Pathology of the vulnerable plaque显示文摘 | Virmani R Burke AP Farb A | | 0，，： | 1 |
| 19 | Childhood food allergy显示文摘 | Burks A W | | 0，，： | 1 |
| 20 | Glutamate transpoi-ters : a key piece in the glutamate puzzle of major depressive disorder显示文摘 | Medina A Burke S Thompson RC | 2013 | J Psyehiatr Res2013，47，9： | 1 |
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