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| 1 | Statin use and risk of diabetes mellitus显示文摘The 3-hydroxy-methylglutaryl coenzyme A reductase inhibitors, statins, are widely used in the primary and secondary prevention of cardiovascular diseases to lower serum cholesterol levels. As type 2 diabetes mellitus is accompanied by dyslipidemia, statins have a major role in preventing the long term complications in diabetes and are recommended for diabetics with normal low density lipoprotein levels as well. In 2012, United States Food and Drug Administration released changes to statin safety label to include that statins have been found to increase glycosylated haemoglobin and fasting serum glucose levels. Many studies done on patients with cardiovascular risk factors have shown that statins have diabetogenic potential and the effect varies as per the dosage and type used. The various mechanisms for this effect have been proposed and one of them is downregulation of glucose transporters by the statins. The recommendations by the investigators are that though statins can have diabetogenic risk, they have more long term benefits which can outweigh the risk. In elderly patients and those with metabolic syndrome, as the risk of diabetes increase, the statins should be used cautiously. Other than a subset of population with risk for diabetes; statins still have long term survival benefits in most of the patients. | Bharti Chogtu Rahul Magazine KL Bairy | 2015 | World Journal of Diabetes2015，6，2： | 8 |
| 2 | Evaluation of antiinflammatory activity of Tephrosia purpurea in rats显示文摘Objective:To evaluate the antiinflammatory activity of orally administered ethanolic extract of Tephrosia purpurea in acute and subacute inflammation in rats.Methods:An ethanolic extract of Tephrosia purpurea was prepared.Carrageenan induced paw edema and cotton pellet granuloma were the models for acute and subacute inflammation respectively.Four groups of rats in each model were treated orally with 2%gum acacia,100 mg /kg of aspirin,500 mg/kg and 1 000 mg/kg of ethanolic extract of Tephrosia purpurea respectively.In carrageenan induced paw edema model, subplantar injection of 1%carrageenan was made into the hind paw of the rats sixty minutes after the administration of the respective drugs.The paw volume was measured immediately after injection of carrageenan,at 3 hours and at 6 hours.Then percentage inhibition of edema was calculated.In the cotton pellet granuloma model,animals were administered drugs for six days after placing cotton pellets in the axilla on each side.On the 7th day,dry weight of granuloma was calculated.Results:The rats treated with Tephrosia purpurea did not exhibit any significant decrease in paw volume and serum ceruloplasmin levels as compared to the control and aspirin treated groups in the acute inflammation model;while,there was a significant(P < 0.01) decrease in the weight of granuloma in Tephrosia purpurea and aspirin treated groups as compared to control in subacute inflammation.Conclusions:The ethanolic extract of orally administered Tephrosia purpurea shows significant antiinflammatory effect in subacute inflammation but not in acute inflammation in rats. | Shenoy Smita Shwetha K Prabhu K Maradi R Bairy KL Shanbhag T | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，3： | 5 |
| 3 | Diagnostic efficacy of Ziehl-Neelsen method against fluorescent microscopy in detection of acid fast bacilli显示文摘Objective:To investigate the application of Ziehl-Neelsen(Z-N) and fluorescent microscopy in detection of acid fast bacilli(AFB).Methods:Duplicate smears were prepared from 260 sputum samples and stained with Z-N and fluorescent staining(FS) methods.The efficiency of both methods in primary diagnosis of tuberculosis were evaluated.Results:The smears were positive for AFB in 15(5.77%) samples by Z-N staining method and in 16(6.15%) samples by FS method.The sensitivity and specificity of Z-N staining method against FS method were 93.75% and 100%respectively.Conclusions:Though lesser cost-effective than Z-N,FS method is a more sensitive and better case finding tool in detection of AFB. | Soham Gupta Vishnu Prasad Shenoy Indira Bairy Muralidharan S | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，4： | 3 |
| 4 | Effect of banana on cold stress test & peak expiratory flow rate in healthy volunteers显示文摘 | Sarkar C Bairy K L Rao N M | 1999 | Indian Journal of Medical Research1999，110，6： | 1 |
| 5 | A new diterpenoid alkaloid isolated from Delphinium caeruleum显示文摘The present study was designed to determine the chemical constituents of Delphinium caeruleum Jacq. ex Camb.. The chemical constituents were isolated and purified by column chromatography with silica gel, ODS, and Sephadex LH-20. Their structures were elucidated by IR, MS, and NMR. Ten compounds were obtained and identified as caerudelphinine A(1), lycoctonine(2), talitine B(3), talitine A(4), talitine C(5), tatsienine-V(6), d-magnoflorine(7), 2-trimethyl-ammonio-3-(3-indolyl) propionate(8), vakhmatine(9), and delatisine(10). Compound 1 was a new lycoctonine-type C19-diterpenoid alkaloid, and compounds 4-10 were isolated from this plant for the first time. | LIN Chao-Zhan LIU Zhu-Jie BAIRI Zeren-Dawa ZHU Chen-Chen | 2017 | Chinese Journal of Natural Medicines2017，15，1： | 1 |
| 6 | Virtual screening of cathepsin k inhibitors using docking and pharmacophore models显示文摘 | Ravikumar M Pavan S Bairy S | 2008 | Chem Biol Drug Des2008，72，1： | 1 |
| 7 | Effect of banana on cold stress test & peak expiratory flow rate in healthy volunteers显示文摘 | Bairy KL Rao NM | 1999 | Indian J Med Res1999，110，： | 1 |
| 8 | Effect of banana on cold stress test & peak expiratory flow rate in healthy volunteers 显示文摘 | Sarkar C Bairy KL Rao NM | 1999 | Indian J Med Res1999，110，： | 1 |
| 9 | Virtual screening of ca-thepsin k inhibitors using docking and pharmacophore models显示文摘 | Ravikumar M Pavan S Bairy S | 2008 | Chem Biol Drug Des2008，71，6： | 1 |
| 10 | Hesperidine, a flavonoid antioxidant decrease oxidative stress and prevent foetal molformations in experimental diabetic pregnancy显示文摘 | OUALI K TREA F TOUMI L BAIRI A MAUREL D GUELLATI M A | 2007 | Phytotherapie ( Paris )2007，5，4： | 1 |
| 11 | A co-assembled gel of a pyromellitic dianhydride derivative and polyaniline with optoelectronic and photovoltaic properties显示文摘 | BAIRI P CHAKRABORTY P SHIT A | 2014 | Langmuir2014，30，： | 1 |
| 12 | Numerical and experimental study of natural convection in tilted parallelepiped cavities for large Rayleigh numbers显示文摘 | Bairi A Laraqi N Garcia de Maria J M | 2007 | Experimental Thermal And Fluid Science2007，31，： | 1 |
| 13 | Theory of thermal resistance between solids with randomly sized and located contacts显示文摘 | Laraqi N Bairi A | 2002 | International Journal of Heat and Mass Transfer2002，45，20： | 1 |
| 14 | Phosphorous and nitrogen dual heteroatom doped mesoporouscarbon synthesized via microwave method for supercapacitor application 显示文摘 | MASINI U B BAIRI V G RAMASAHAYAM S K | 2014 | Journal of Power Sources2014，250，3： | 1 |
| 15 | Comparison of the efficacy of carbamazepine,gabapentin and lamotrigine for neuropathic pain in rats显示文摘 | Chogtu B Bairy KL Smitha D | 2011 | Indian J Pharmacol2011，43，5： | 1 |
| 16 | Comparison of efficacyof carbamasepin gabapentin and lamotrigine for neuropathic painin rats显示文摘 | Bharti Chogtu Bairy K L Smitha D | 2011 | Indian J Pharmacol2011，43，5： | 1 |
| 17 | Hesperidine,a flavonoid antioxidant decrease oxidative stress and prevent foetal molformations in experimental diabetic pregnancy 显示文摘 | OUALI K TREA F TOUMI L BAIRI A MAUREL D GUELLATI M A | 2007 | Phytotherapie (Paris)2007，5，4： | 1 |
| 18 | Nusselt-Rayleigh correlations for design of industrial elements : experimental and numerical investigation of natural convection in tilted square air filled enclosures 显示文摘 | Bairi A | 2008 | Energy Conversion and Management2008，49，： | 1 |
| 19 | Diagrams for fast transient conduction in sphere and long cylinder subject to sudden and violent thermal effects on its surface显示文摘 | Abderrahmane Bairi Najib Laraqi | 2003 | Applied Thermal Engineering2003，23，： | 1 |
| 20 | pH and anion sensitive silver ( I ) coordinated melamine hydrogel with dye absorbing properties: metastability at low melamine concentration显示文摘 | BAIRI P ROY B NANDI A K | 2011 | J Mater Chem2011，21，11： | 1 |
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