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| 1 | Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?显示文摘AIM:To evaluate the overlap of autoimmune hepatitis in hepatitis C virus(HCV)-infected patients with intense interface hepatitis.METHODS:Among 1759 patients with hepatitis C submitted to liver biopsy,92(5.2%) presented intense interface hepatitis.These patients were evaluated regarding the presence of antinuclear antibody(ANA),anti-smooth muscle antibody(SMA) and anti-liver/kidney microsomal antibody(LKM-1),levels of γ-globulin and histological findings related to autoimmune hepatitis(plasma cell infiltrate and presence of rosettes).RESULTS:Among patients with hepatitis C and intense interface hepatitis there was a low prevalence of autoantibodies(ANA=12%,SMA=5%,LKM-1=0%) and the median γ-globulin level was within the normal range.Typical histological findings of autoimmune disease were observed in only two cases(2%).After applying the score for diagnosis of autoimmune hepatitis,only one patient was classified with a definitive diagnosis of autoimmune hepatitis.Since overlap with autoimmune hepatitis was not the explanation for the intense necroinflammatory activity in patients with chronic hepatitis C we sought to identify the variables associated with this finding.The presence of intense interface hepatitis was associated with more advanced age,both at the time of infection and at the time of the biopsy,and higher prevalence of blood transfusion and alcohol abuse.CONCLUSION:Although possible,overlap with autoimmune hepatitis is a very rare association in HCV-infected patients with intense interface hepatitis,an unusual presentation which seems to be related to other host variables. | Rosilene G Badiani Vitória Becker Renata M Perez Carla AL Matos Lara B Lemos Valéria P Lanzoni Luis Eduardo C Andrade Alessandra Dellavance Antonio Eduardo B Silva Maria Lucia G Ferraz | 2010 | World Journal of Gastroenterology2010，16，29： | 7 |
| 2 | Vulnerability of the nigrostriatal system as detected by transcranial ultrasound显示文摘 | Berg D Becker G Zeiler B | 1999 | Neurology1999，53，： | 2 |
| 3 | Mean platelet volume as a predictor of cardiovascular risk: a systematic review and meta-anal- ysis 显示文摘 | Chu S G Becker R C Berger P B | 2010 | J Thromb Haemost2010，8，1： | 1 |
| 4 | Middle east respiratory syndrome eoronavirus spike protein delivered by modified vaccinia virus ankara effi- ciently induces virus-neutralizing antibodies显示文摘 | Song F Fux R Provacia L B Volz A Eickmann M Becker S Osterhaus A D Haagmans B L Sutter G | 2013 | J Vir ol2013，87，11： | 1 |
| 5 | Comparison of rape- seed cuhivars and resynthesized lines based on allozyme and RFLP markers显示文摘 | Becker H Engqvist G Karlsson B | 1995 | Theor Appl Genet1995，91，： | 1 |
| 6 | Expression of luteinizing hormone-releasng hormone and its recepter in porcine immune tissues显示文摘 | WEESNER G D BECKER B A MATTERI R L | 1997 | Life Sci1997，61，17： | 1 |
| 7 | Vulnerability of the nigrostriatal system as detected by transcranial ultrasound显示文摘 | Berg D Becker G Zeiler B | 2001 | Neurology2001，53，： | 1 |
| 8 | Evaluation of candidate vaccine approaches for mers-cov显示文摘 | Wang L Shi W Joyce M G Modjarrad K Zhang Y Leung K Lees C R Zhou T Yassine H M KanekiyoM Yang Z Y Chen X Becker M M Freeman M Vogel L Johnson J C Olinger G Todd J P Bagci U Solomon J Mollura D J Hensley L Jahrling P Deni- son M R Rao S S Subbarao K Kwong P D Mascola J R Kong W P Graham B S | 2015 | Nat Commun2015，6，： | 1 |
| 9 | Education and the distribu- tion of earnings显示文摘 | Becker G S Chiswick B R | 1966 | American Economic Review1966，56，1： | 1 |
| 10 | Proctitis after external-beam radiotherapy for prostate cancer classified by Vienna Rectoscopy Score and correlated with EORTC/RTOG score for late rectal toxicity: results of a prospective multicenter study of 166 patients显示文摘 | Goldner G Tomicek B Becker G | 2007 | Int J Radiat Oncol Biol Phys2007，67，1： | 1 |
| 11 | Identifying optimal spectral bands from in situ measurements of Great Lakes coastal wetlands using second-derivative analysis显示文摘 | BECKER B L DAVID P L QI J G | 2005 | Remote Sensing of Environment2005，97，2： | 1 |
| 12 | The endogenous determination of time preference显示文摘 | Becker G S Mulligan C B | 1997 | The Quarterly Journal of Eco- nomics1997，112，3： | 1 |
| 13 | World Journal of Urology显示文摘 | Uckert S Becker A J Ness B O Stief C G Scheller F Knapp W H Jonas U | 2003 | 4(6):3232003，4，6： | 1 |
| 14 | Gene cloning, overproduction and purification of a functionally active cytoplasmic fatty acid-binding protein (SJ-FABPS) from the human blood fluke Schistosoma japonicun 显示文摘 | BECKER M M KALINNA B H WAINE G J | 1994 | Gene1994，148，2： | 1 |
| 15 | Induction of Hsp90 protein expression in malignant melanomas anti melanoma metastases 显示文摘 | Becker B Multhoff G Farkas B | 2004 | Exp Dermatol2004，13，1： | 1 |
| 16 | Increased extracellular dopamine in the nucleus accumbens and striatum of the female rat during paced copulatory behavior 显示文摘 | Mermelstein P G Becker J B | 1995 | Behav Neurosci1995，109，2： | 1 |
| 17 | A rheological investigation of the behaviour of two Southern African platinum ores显示文摘 | BECKER M YORATH G NDLOVU B | 2013 | Minerals Engineering2013，，49： | 1 |
| 18 | A predictive controller for autonomous vehicle path tracking 显示文摘 | RAFFO G V GOMES G K NORMEY-RICO J E KELBER C R BECKER L B | 2009 | IEEE Transactions on Intelligent Transportation Systems2009，10，1： | 1 |
| 19 | Copper- catalyzed Suzuki cross-coupling using mixed nanocluster catalysts 显示文摘 | THATHAGAR M B BECKERS J ROTHENBERG G | 2002 | J Am Chem Soc2002，124，40： | 1 |
| 20 | Genetic algorithm for variable ordering of OBDDs显示文摘 | Drechsler R Becker B Gckel N | 1996 | IEE Proceedings-Computers and Digital Techniques1996，143，6： | 1 |
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