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| 1 | Relationship between the severity of hepatitis C virus-related liver disease and the presence of Helicobacter species in the liver: A prospective study显示文摘AIM: To determine the presence of Helicobacter species DNA in the liver of chronic hepatitis C (CHC) patients with and without cirrhosis as compared to controls, and to identify the bacterial species involved. METHODS: Seventy-nine consecutive patients (HBV and HIV negative) with a liver sample obtained after liver biopsy or hepatic resection were studied: 41 with CHC without cirrhosis, 12 with CHC and cirrhosis, and 26 controls (HCV negative). Polymerase chain reactions (PCRs) targeting Helicobacter 16S rDNA and species- specific were performed on DNA extracted from the liver. A gastric infection with H pylori was determined by serology and confirmed by 13C-urea breath test. RESULTS: Overall, Helicobacter 16S rDNA was found in 16 patients (20.2%). Although positive cases tended to be higher in CHC patients with cirrhosis (41.6%) than in those without cirrhosis (17.0%) or in controls (15.4%), the difference was not statistically significant (P =0.08). H pylori-like DNA was identified in 12 cases and H. pullorum DNA in 2, while 2 cases remained unidenti- fied. Gastric infection with H pylori was found in only 2 of these patients. CONCLUSION: Our results do not confirm the associ- ation of Helicobacter species DNA in the liver of CHC patients with advanced liver disease. The lack of correlation between positive H pylori serology and the presence of H pylori-like DNA in the liver may indicate the presence of a variant of this species. | Laurent Castéra Anne Pedeboscq Marcia Rocha Brigitte Le Bail Corinne Asencio Victor de Lédinghen Pierre-Henri Bernard Christophe Laurent Marie-Edith Lafon Maylis Capdepont Patrice Couzigou Paulette Bioulac-Sage Charles Balabaud FrancisMégraud Armelle Ménard | 2006 | World Journal of Gastroenterology2006，12，45： | 3 |
| 2 | Prevalence and factors associated with failure of liver stiffness measurement using FibroScan in a prospective study of 2114 examinations显示文摘 | Juliette Foucher Laurent Castéra Pierre-Henri Bernard Xavier Adhoute David Laharie Julien Bertet Patrice Couzigou Victor de Lédinghen | 2006 | European Journal of Gastroenterology & Hepatology2006，，4： | 3 |
| 3 | Early detection in routine clinical practice of cirrhosis and oesophageal varices in chronic hepatitis C: Comparison of transient elastography (FibroScan) with standard laboratory tests and non-invasive scores显示文摘 | Laurent Castéra Brigitte Le Bail Fran?oise Roudot-Thoraval Pierre-Henri Bernard Juliette Foucher Wassil Merrouche Patrice Couzigou Victor de Lédinghen | 2008 | Journal of Hepatology2008，，1： | 1 |
| 4 | Use of cone-beam volumetric tomography in the diagnosis of root fractures显示文摘 | Bernardes RA de Moraes IG Húngaro Duarte MA | 2009 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod2009，108，2： | 1 |
| 5 | Use of cnebeam volumetric tomography inthe diagnosis ofroot fractures 显示文摘 | Bernardes RA de Moraes IG Hungaro Duarte MA | 2009 | OralSurg OralMedOral PatholOralRa diolEndod2009，108，2： | 1 |
| 6 | Pitfalls of liver stiffness measurement:a 5-year prospective study of 13,369 examinations显示文摘 | Castéra L Foucher J Bernard PH | | 0，，03： | 1 |
| 7 | Influence of embedding media on the assessment of electronic apex locators显示文摘 | Baldi JV Victorino FR Bernardes RA | 2007 | J Endod2007，33，4： | 1 |
| 8 | Root canal area increase promoted by the EndoSequence and ProTaper systems:comparison by computed tomography显示文摘 | Bernardes RA Rocha EA Duarte MA | 2010 | J Endod2010，36，7： | 1 |
| 9 | Prevalence and factors associated with failure of liver stiffness measurement using Fibro- Scan in a prospective study of 2114 examinations显示文摘 | Foucher J Castéra L Bernard PH | 2006 | Eur J Gas- troenterol Hepatol2006，18，4： | 1 |
| 10 | Bilateral mandibular canines with two roots and two separate canals:case report显示文摘 | Victorino FR Bernardes RA Baldi JV | 2009 | Braz Dent J2009，20，1： | 1 |
| 11 | A progression puzzle显示文摘 | Bernards R Weinberg RA | 2002 | Nature2002，，6900： | 1 |
| 12 | Root canal area increase promoted by the EndoSequence and Pro-Taper systems:comparison by computed tomography显示文摘 | Bernardes RA Rocha EA Duarte MA | | 0，，7： | 1 |
| 13 | Use of cone-beam volumetric tomography in the diagnosis of root frac- tures 显示文摘 | Bernardes RA de Moraes IG Duarte MA | 2009 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod2009，108，2： | 1 |
| 14 | Pitfalls of liver stiffness measurement:a 5-vear prospective study of 13,369examinations显示文摘 | Castéra L Foucher J Bernard P H | | 0，，03： | 1 |
| 15 | Antibiotic efficacy against Staphylococcus epidermidis adherent to vascular grafts显示文摘 | Bergamini TM McCurry TM Bernard JD Hoeg KL Corpus RA Peyton JC | 1996 | J Surg Res1996，60，1： | 1 |
| 16 | Use of cone-beam volumetric in the diagnosis of root frac-tures 显示文摘 | Bernardes RA de Moraes IG Hungaro Duarte MA | 2009 | Oral Surg Oral Med Oral Pathol Oral RadiolEndod2009，108，2： | 1 |
| 17 | System for stable expression of short interfering RNAs in mammalian cells显示文摘 | Brummelkamp TR Bernards R Agami RA | 2002 | Science2002，296，5567： | 1 |
| 18 | Use of cone-beam volumetric tomography in the diagnosis of root fractures 显示文摘 | Bernardes RA de Moraes IG Hungaro Duarte MA | 2009 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod2009，108，： | 1 |
| 19 | Impaired thyroxine and 3,5,3'-triiodothyronine handling by rat hepatocytes in the presence of serum of patients with nonthyroidal illness显示文摘 | Vos RA de Jong M Bernard BF | 1995 | J Clin Endocrinol Metab1995，80，： | 1 |
| 20 | Use of cone-beam volumetric tomography in the diagnosis of root fractures显示文摘 | Bernardes RA de Moraes IG Húngaro Duarte MA | 2009 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod2009，108，2： | 1 |
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