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| 1 | 微创牙科学:文献回顾与最新进展(英文)显示文摘微创牙科学是指采用生物学方法而不是传统的牙体手术处理龋病,以最大限度地减少对牙体结构的破坏。这种新的龋病处理方法,将过去强调的视龋损为“洞”而反复充填的理念,转变为视龋损为口腔生态失衡而促使生物膜产生生物学变化。微创牙科学的目的在于阻止龋病进程,然后修复缺失的牙体结构和功能,最大限度地发挥牙体的愈合潜能。微创牙科学的处理方法可概括为3个步骤:(1)判定患者的患龋风险;(2)再矿化,即防止龋损形成并逆转未形成“洞”的浅龋;(3)修复,即控制龋活性,使愈合潜能最大化并修复龋损。龋病并非仅仅是牙体脱矿,而是一个因生物膜与牙界面生态和化学平衡失衡而致的反复的脱矿过程(生态菌斑学说)。饮食和生活方式(尤其是碳水化合物的摄入频次)、饮水、吸烟是导致生物膜生态和致病性的重要因素。椅旁评价菌斑和唾液的方法的问世,使得龋病危险评估和监测患者的顺从性成为可能。唾液的再矿化特性,可以通过使用能够释放Ca2+、P5+、F1-的再矿化剂(CPP-ACPandCPP-ACFP)而予强化。使用某些化学制剂(氟、氯已定和木糖醇),可改变菌斑的致病性。采用微创治疗方案,可修复早期龋损,增进患者的理解力和顺从性。本文从3个方面,详细论述了微创牙科学的概念、理论基础和操作方法。 | Andrew M. Brostek Andrew J. Bochenek Laurence J. Walsh | 2006 | 上海口腔医学2006，15，3： | 12 |
| 2 | Effect of CD14/TLR4 antagonist on GnRH/LH secretion in ewe during central inflammation induced by intracerebroventricular administration of LPS显示文摘Background: Immune stress induced by lipopolysaccharide(LPS) influences the gonadotropin-releasing hormone(GnRH)/luteinizing hormone(LH) secretion. Presence of LPS interacting Toll-like receptor(TLR) 4 in the hypothalamus may enable the direct action of LPS on the GnRH/LH secretion. So, the aim of the study was to investigate the influence of intracerebroventricular(icv) injection of TLR4 antagonist on GnRH/LH secretion in anestrous ewes during LPS-induced central inflammation. Animals were divided into three groups icv-treated with: Ringer-Locke solution, LPS and TLR4 antagonist followed by LPS.Results: It was demonstrated that TLR4 antagonist reduced LPS-dependent suppression of GnRH gene expression in the preoptic area and in the medial basal hypothalamus, and suppression of receptor for GnRH gene expression in the anterior pituitary gland. It was also shown that TLR4 antagonist reduced suppression of LH release caused by icv injection of LPS. Central administration of LPS stimulated TLR4 gene expression in the medial basal hypothalamus.Conclusions: It was indicated that blockade of TLR4 prevents the inhibitory effect of centrally acting LPS on the GnRH/LH secretion. This suggests that some negative effects of bacterial infection on the hypothalamic-pituitary-gonadal axis activity at the hypothalamic level may be caused by central action of LPS acting through TLR4. | Karolina Haziak Andrzej Przemyslaw Herman Karolina Wojtulewicz Bartosz Pawlina Kamila Paczesna Joanna Bochenek Dorota Tomaszewska-Zaremba | 2018 | Journal of Animal Science and Biotechnology2018，9，4： | 2 |
| 3 | Eradication of Helicobacter pylori be 7-day triple-therapy regimens combining pantoprazole with clarithromycin,metronidazole,or amoxicinllin in patients with peptic ulcer disease:Results of two double-blind,randomized studies显示文摘 | Bochenek WJ Peters S Praga PD | 2003 | Heloicobacter2003，8，： | 1 |
| 4 | Structural analysis of the MgAl5 matrix cast composites containing SiC particles显示文摘 | BOCHENEK A BRASZCZYSKA K N | 2000 | Materials Science and Engineering2000，290，1： | 1 |
| 5 | Thermal degradation of joined thick Au and A1 elements显示文摘 | BOCHENEK A BOBER B HAUFFE W | 2004 | Microelectronics International2004，21，1： | 1 |
| 6 | A Web-based System for Design Artifact Modeling 显示文摘 | Szykman S Racz J Bochenek C | 2000 | Design Studies2000，，： | 1 |
| 7 | Multicomponent ceramic materials on the basis of PZT for the production of piezoelectric resonators显示文摘 | Bochenek D Surowiak Z Gavrilyachenko S V | 2005 | Archives of Acoustics2005，30，1： | 1 |
| 8 | Acute and late outcomes of unprotected left main stenting in comparison with surgical revasculariza- tion 显示文摘 | Buszman PE Kiesz SR Bochenek A | 2008 | J Am Coil Cardiol2008，51，5： | 1 |
| 9 | Value of speckle-tracking echocardiography for prediction of left ventricular remodeling in patients with ST-elevation myocardial infarction treated by primary percutaneous intervention显示文摘 | Bochenek T Wita K Tabor Z | 2011 | J Am Soc Echocardiogr2011，24，12： | 1 |
| 10 | Multicomponent ceramic materials on the basis of PZT for the production of piezoelectric resonators显示文摘 | BOCHENEK D SUROWIAK Z GAVRILYACHENKO S V | 2005 | Archives of Acoustics2005，30，1： | 1 |
| 11 | A compound RiemannHilbert problem for holomorphic functions with nonlinear boundary condition显示文摘 | Wolfersdorf L V Bochenek J W | 1984 | Demonstration Math1984，2，： | 1 |
| 12 | Non-invasive Electrical Stimulation of the Ear Canal as a Communication Aid in Acquired Total Deafness显示文摘 | Bochenek W | 1989 | British Journal of Audiology1989，23，4： | 1 |
| 13 | Novel local rules of cellular automata applied to topology and size optimization 显示文摘 | Bochenek B Tajs-Zieliflska K | 2012 | Engineering Optimization2012，44，1： | 1 |
| 14 | Cell cycle analysis of somatic cell lines in the cloning of the domestic cat显示文摘 | Bochenek M Katska L Kania G | 2001 | Theriogenology2001，55，： | 1 |
| 15 | A note on effect of benzoic acid supplementation onthe performance and microbiota population of broilerchickens 显示文摘 | J6ZEFIAK D KACZMAREK S BOCHENEK M etal | 2007 | Journal of Animal and Feed Sciences2007，16，2： | 1 |
| 16 | The first example of anti-Dia antibody in Poland显示文摘 | Kusnierz-Alejska G Bochenek S Zukowska B | 1990 | Mater Med Pol1990，22，1： | 1 |
| 17 | Acute andlate outcomes of unprotected left main stenting in comparisonwith surgical revascularization 显示文摘 | BUSZMAN P E KIESZ S R BOCHENEK A | 2008 | J Am Coll Cardiol2008，51，5： | 1 |
| 18 | Multicomponent ceramic materials on the basis of PZT for the production of piezoelectric resonators 显示文摘 | Bochenek D Surowiak Z Gavrilyachenko S V | 2005 | Archives of Acoustics2005，30，1： | 1 |
| 19 | Flow cytometric cell cycle a- nalysis of somatic cells primary cultures established for bovine clo- ning显示文摘 | Katska L Bochenek M Kania G | 2002 | Theriogenology2002，58，9： | 1 |
| 20 | Flow cytometric cell cycle analsysis of non-cultured and cultured bovine somatic cells 显示文摘 | Katska L Bochenek B Rynska B | 2000 | Theriogenology2000，53，： | 1 |
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