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| 1 | Prediction of delayed graft function using different scoring algorithms: A single-center experience显示文摘AIM To compare the performance of 3 published delayed graftfunction(DGF) calculators that compute the theoretical risk of DGF for each patient.METHODS This single-center,retrospective study included 247 consecutive kidney transplants from a deceased donor.These kidney transplantations were performed at our institution between January 2003 and December 2012.We compared the occurrence of observed DGF in our cohort with the predicted DGF according to three different published calculators. The accuracy of the calculators was evaluated by means of the c-index(receiver operating characteristic curve).RESULTS DGF occurred in 15.3% of the transplants under study.The c index of the Irish calculator provided an area under the curve(AUC) of 0.69 indicating an acceptable level of prediction,in contrast to the poor performance of the Jeldres nomogram(AUC = 0.54) and the Chapal nomogram(AUC = 0.51). With the Irish algorithm the predicted DGF risk and the observed DGF probabilities were close. The mean calculated DGF risk was significantly different between DGF-positive and DGF-negative subjects(P < 0.0001). However,at the level of the individual patient the calculated risk of DGF overlapped very widely with ranges from 10% to 51% for recipients with DGF and from 4% to 56% for those without DGF.The sensitivity,specificity and positive predictive value of a calculated DGF risk ≥ 30% with the Irish nomogram were 32%,91% and 38%. CONCLUSION Predictive models for DGF after kidney transplantation are performant in the population in which they were derived,but less so in external validations. | Magda Michalak Kristien Wouters Erik Fransen Rachel Hellemans Amaryllis H Van Craenenbroeck Marie M Couttenye Bart Bracke Dirk K Ysebaert Vera Hartman Kathleen De Greef Thiery Chapelle Geert Roeyen Gerda Van Beeumen Marie-Paule Emonds Daniel Abramowicz Jean-Louis Bosmans | 2017 | World Journal of Transplantation2017，7，5： | 3 |
| 2 | Increased plasma concentrations of interleukin-6,soluble interleukin-6,soluble interleukin-2 and transferring receptor in major depression显示文摘 | Maes M Mehzer H Bosmans E | 1995 | J Affect Disord1995，34，4： | 1 |
| 3 | In vivo immunomodulatory effects of clozapine in schizophrenia显示文摘 | Maes M Bosmans E Kenis G | 1997 | Schizo Res1997，26，： | 1 |
| 4 | A comparison of three finite element models of edentulous mandible provided with implants显示文摘 | Meijer H J A Starmans F J M Bosman F | 1993 | Journal Oral Rehabil1993，20，2： | 1 |
| 5 | Possible mechanisms of collar induced inritual thickening显示文摘 | De Meyer G R Van Put D J Kockx M M Van Schil P Bosmans R Bult H | 1997 | Arterioscler Thromb Vasc Biol1997，17，： | 1 |
| 6 | Plasma glutamine depletion and patient outcome in acute ICU admissions显示文摘 | Oudemans-van Straaten H M Bosman R J | 2001 | Intensive Care Med2001，27，： | 1 |
| 7 | Controlled free-radical polymerization显示文摘 | Bosman A W Fréchet J M J Hawker C J | 2001 | Polym Mater Sci Eng2001，84，： | 1 |
| 8 | Live Animal and Carcass Characteristics of South African Indigenous Goats 显示文摘 | SIMELA L WEBB E C BOSMAN M J C | 2011 | South African Journal of Animal Science2011，41，1： | 1 |
| 9 | Combination therapy with rofecoxib and finasteride in the treatment of men with lower urinary tract symptoms (LUTS)and benign prostatic hyperplasia (BPH) 显示文摘 | Di Silverio F Bosman C Salvatori M | 2005 | Eur Urol2005，47，： | 1 |
| 10 | Inter- leukin - 2 and interleukin - 6 in schizophrenia and mania: Effects of neuroleptics and mood stabilizers显示文摘 | Maes M Bosmans E Cadobrese J | 1995 | Paychiatry Res1995，29，： | 1 |
| 11 | The integration of PET-CT scans from different hospitals into radiotherapy treatment planning 显示文摘 | Oilers M Bosmans G van Baardwijk A | 2008 | Radiother Oncol2008，87，1： | 1 |
| 12 | The proteome of red cell membranes and vesicles during storage in blood bank conditions显示文摘 | Bosman GJ Lasonder E Lnten M | 2008 | Transfusion2008，48，： | 1 |
| 13 | Citrate anticoagulation for continuous venovenous hemofiltration显示文摘 | Ou H M Bosman R J Koopmans M | 2009 | Crit Care Med2009，37，2： | 1 |
| 14 | Combination therapy with rofe-coxib and finasteride in the treatment of men with lower urinary tractsymptoms(LUTS)and benign prostatic hyperplasia(BPH)显示文摘 | Di Silverio F Bosman C Salvatori M | 2005 | EurUrol2005，47，1： | 1 |
| 15 | An innovative team-based stop smoking competition among Maori and Pacific Is- land smokers: rationale and method for the study and its evalua- tion显示文摘 | Glover M Bosman A Wagemakers A | 2013 | BMC Public Health2013，13，： | 1 |
| 16 | About dendrimers : structure, physical properties, and applica- tions显示文摘 | BOSMAN A W JANSSEN H M MEIJER E W | 1999 | Chem Rev1999，99，7： | 1 |
| 17 | Measuring the Digital Divide in the United States: Race Ownership显示文摘 | Jayajit Chakraborty M Martin Bosman | 2005 | The Professional Income and Personal Computer Geographer2005，57，3： | 1 |
| 18 | Incidence of C4d stain in Protocol biopsies from renal allografts:results from a multicenter trial显示文摘 | Bogers J Bosmans JL | 2005 | Am J Transplant2005，5，5： | 1 |
| 19 | Histogenesis of the chequered pattern of the African elephant (Loxodonta Africana)显示文摘 | RAUBENHEIMER E J BOSMAN M C VOSTER R | 1998 | Arch Oral Biology1998，43，： | 1 |
| 20 | Increased plasma concentrations of interleukin-6,soluble interleukin-6 receptor,soluble interleukin-2 receptor and transferrin receptor in major depression显示文摘 | Maes M Meltzer H Bosmans E | 1995 | J Affect Disord1995，34，4： | 1 |
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