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| 1 | Outcome of gall bladder polypoidal lesions detected by transabdominal ultrasound scanning: A nine year experience显示文摘AIM: To determine the outcome of polypoidal lesions within the gall bladder (PLG) diagnosed by trans-abdominal scanning.METHODS: A nine-year (1993-2002) retrospective casenote review of all patients who underwent ultrasound scanning after referral to a single Upper GI Surgeon at a District General Hospital was conducted. Patients who were diagnosed with a PLG were included in our study. A database was constructed and patient details, investigations including ultrasound scan (USS) findings, treatment and histology and final diagnosis were recorded. RESULTS: Twenty-three (out of 651) patients were diagnosed pre-operatively by USS to have a polyp-likegall bladder lesion (PLG). Post cholecystectomy histological examination revealed 12 gallstones, 7 cholesterol polyps, 3 adenocarcinomas within polyps and 1 normal gall bladder. The specificity of USS in the diagnosis of PLG was 92.3%. All the true polyps were malignant. Overall USS had 66.66% sensitivity and 100% specificity in the pre-operative suspicion of malignancy. Using size greater than 10 mm as measured on USS as a cut-off, we find 100% sensitivity and 86.95% specificity with a positive predictive value of 50% in the diagnosis of malignancy in PLG.CONCLUSION: A large number of PLG are in fact calculi within diseased gall bladder. In cases of gall bladder polyps more then 10 mm in size on USS further imaging (crosssectional and/or EUS) is indicated prior to surgery. This will help in the optimal management of patients and avoid histological surprises. | D Chattopadhyay R Lochan S Balupuri BR Gopinath KS Wynne | 2005 | World Journal of Gastroenterology2005，11，14： | 23 |
| 2 | Safety of the long-term use of proton pump inhibitors显示文摘The proton pump inhibitors (PPIs) as a class are remarkably safe and effective for persons with peptic ulcer disorders. Serious adverse events are extremely rare for PPIs, with case reports of interstitial nephritis with omeprazole, hepatitis with omeprazole and lansoprazole, and disputed visual disturbances with pantoprazole and omeprazole. PPI use is associated with the development of fundic gland polyps (FGP); stopping PPIs is associated with regression of FGP. In the absence of Helicobacter pylori infection, the long-term use of PPIs has not been convincingly proven to cause or be associated with the progression of pre-existing chronic gastritis or gastric atrophy or intestinal metaplasia. Mild/modest hypergastrinemia is a physiological response to the reduction in gastric acid secretion due to any cause. The long-term use of PPIs has not been convincingly proven to cause enterochromaff in-like cell hyperplasia or carcinoid tumors. PPIs increase the risk of community acquired pneumonia, but not of hospital acquired (nosocomial) pneumonia. There is no data to support particular care in prescribing PPI therapy due to concerns about risk of hip fracture with the long-termuse of PPIs. Long-term use of PPIs does not lead to vitamin B12 def iciencies, except possibly in the elderly, or in persons with Zollinger-Ellison Syndrome who are on high doses of PPI for prolonged periods of time. There is no convincingly proven data that PPIs increase the risk of Clostridium difficile-associated diarrhea in persons in the community. The discontinuation of PPIs may result in rebound symptoms requiring further and even continuous PPI use for suppression of symptoms. As with all medications, the key is to use PPIs only when clearly indicated, and to reassess continued use so that long-term therapy is used judiciously. Thus, in summary, the PPIs are a safe class of medications to use longterm in persons in whom there is a clear need for the maintenance of extensive acid inhibition. | Alan BR Thomson Michel D Sauve Narmin Kassam Holly Kamitakahara | 2010 | World Journal of Gastroenterology2010，16，19： | 20 |
| 3 | Is rectal indomethacin effective in preventing of post-endoscopic retrograde cholangiopancreatography pancreatitis?显示文摘AIM:To investigate the effectiveness of rectally administered indomethacin in the prophylaxis of post-endoscopic retrograde cholangiopancreatography(ERCP)pancreatitis and hyperamylasaemia in a multicentre study.METHODS:A prospective,randomised,placebocontrolled multicentre study in five endoscopic units was conducted on 686 patients randomised to receive a suppository containing 100 mg indomethacin,or an inert placebo,10-15 min before ERCP.Post-ERCP pancreatitis and hyperamylasaemia were evaluated 24 h following the procedure on the basis of clinical signs and laboratory parameters,and computed tomography/magnetic resonance imaging findings if required.RESULTS:Twenty-one patients were excluded because of incompleteness of their data or because of protocol violation.The results of 665 investigations were evaluated:347 in the indomethacin group and 318 in the placebo group.The distributions of the risk factors in the two groups did not differ significantly.Pancreatitis developed in 42 patients(6.3%):it was mild in34(5.1%)and severe in eight(1.2%)cases.Hyperamylaesemia occurred in 160 patients(24.1%).There was no significant difference between the indomethacin and placebo groups in the incidence of either postERCP pancreatitis(5.8%vs 6.9%)or hyperamylasaemia(23.3%vs 24.8%).Similarly,subgroup analysis did not reveal any significant differences between the two groups.CONCLUSION:100 mg rectal indomethacin administered before ERCP did not prove effective in preventing post-ERCP pancreatitis. | Zoltán Dbrnte Zoltán Szepes Ferenc Izbéki Judit Gervain László Lakatos Gyula Pécsi Miklós Ihász Lilla Lakner Erzsébet Toldy László Czakó | 2014 | World Journal of Gastroenterology2014，20，29： | 16 |
| 4 | Enhanced fat degradation following the addition of a Pseudomonas species to a bioaugmentation product used in grease traps显示文摘The presence of fats, oils and greases(FOGs) in wastewater can lead to many problems including blockages. Investigation of a bioaugmentation product, consisting of Bacillus spp., to degrade butter(1%, W/V) and olive oil(1%, V/V) was performed in aerobic batch cultures for 13-day incubation. Gravimetric analysis of the remaining substrates showed slowly degradation of the oil after a 2-day lag, but no degradation of the butter. Addition of a Pseudomonas putida strain CP1 to the Bacillus spp. population promoted rapidly degradation of both fats after7 days of incubation. High fat accumulation revealed the potential use of the new bacterial mixture for production of added-value compounds. Lipase production only by the Bacillus spp.along with the analysis of the remaining lipids with thin layer chromatography and gas chromatography, suggested that the Bacillus spp. mainly only hydrolyzed the fat. The breakdown products were metabolized by the Pseudomonas putida CP1 performing preferential utilization of unsaturated fatty acids. Investigation of population dynamics using selective plating and a labeled Pseudomonas putida CP1::Tn7-gfp showed domination of the latter. The new mixture performed a successful cooperation with good potential for FOG treatment and an aggregative response desirable to fat degradation in grease traps. | Markella Tzirita Seraphim Papanikolaou Bríd Quilty | 2019 | Journal of Environmental Sciences2019，31，3： | 2 |
| 5 | Optimization of Mo/Cu(In,Ga)Se2/CdS/ZnO Hetero-Junction Solar Cell Performance by Numerical Simulation with SCAPS-1D显示文摘The paper presents a one-dimensional simulation study of chalcopyrite Cu(In,Ga)Se2(CIGS)solar cells,where the effects of the variation of CIGS,CdS,and ZnO layers are presented.Additionlly the influence of the variation of doping and the defects density of shallow uniform donors and acceptors types are also presented.The analyse of the simulation results shows that recombination inside the space charge region(SCR)decrease more our CIGS solar cell model performance.We also found that the electrical parameters increase with increasing CIGS absorber doping density exception of JSC values that reach their maximum at 1016cm-3 and decrease due to recombination of charge carriers in the p-n junction particularly the recombination inside the SCR.We also stressed the fact that the effects of shallow uniforme donor density is very low on the performance of our CIGS solar cell model is important because it will allow to control the width of space charge region from shallow uniform acceptors defect density that has a strong influence on the different electrical parameters.Yet,good optimization of performance of the CIGS-based solar cell necessarily passes though a good control of the space charge region width and will constitute a boosting perspective for the preparation of our next paper.We contact that the results obtained of the numerical simulation with SCAPS-1D show a good agreement comparatively of the literature results.The simulation of our CIGS solar cell presents best performances if the values of the absorber layer thickness is in the range of 0.02 to 0.03μm,the buffer layer thickness is in the range of 0.02 to 0.06μm and the defects density of shallow uniform acceptors types is in the range of 1015 to 1017cm-3. | Adama Zongo Daouda Oubda Soumaïla Ouédraogo Marcel Bawindsom Kébré Alain Diasso Issiaka Sankara Boureima Traore François Zougmoré Zacharie Koalga Frédéric Ouattara | 2021 | 材料科学与工程(中英文B版)2021，11，4： | 2 |
| 6 | Prise en charge chirurgicale de la pancréatite chronique显示文摘 | Jean-Marc Regimbeau Frédéric Dumont Thierry Yzet Denis Chatelain éric Bartoli Franck Brazier Olivier Bréhant Jean-Louis Dupas Fran?ois Mauvais Richard Delcenserie | 2007 | Gastroenterologie Clinique et Biologique2007，，8： | 2 |
| 7 | 电渣重熔满足大型锻件的要求显示文摘与锭模浇注出低密度、带缩孔铸锭相比,高性能铸锭材料的生产趋于用重熔设备来实现,铸锭的力学性能也会更均匀。水冷铜结晶器中重熔的铸锭具有较高的材料产出量,从而使具有相同最终外形的铸锭其单锭的质量更小,密度更接近于锻造的材料。因此,后续的锻造工艺不需要高锻造比来生产高密度铸锭。在100t以下的铸锭通常可以在固定锭模中生产,并配以外部底加热装置,以避免可能的铸锭底部开裂;50t以上的铸锭采用高度复杂的拉锭系统配以多电极交换,在短的环形坩埚中重熔技术才是最经济的。大型的带有电极交换技术的电渣重熔炉,为生产超过钢厂中最大单个钢包浇铸质量的大尺寸铸锭提供了可能性。介绍了生产145t重铸锭的炉型设计。对于容易出现开裂的高度复杂的合金,可以通过应用隔热绝缘来生产。 | H Scholz U Biebricher G Brückmann D Esser | 2013 | 钢铁2013，48，10： | 2 |
| 8 | On the transfer of the Fusarium toxins deoxynivalenol (DON) and zearalenone (ZON) from sows to their fetuses during days 35–70 of gestation显示文摘 | T. Goyarts S. D?nicke K.-P. Brüssow H. Valenta K.-H. Uebersch?r U. Tiemann | 2007 | Toxicology Letters2007，，1： | 2 |
| 9 | Survival after cor-onary revascularization among patients with kidney disease显示文摘 | Hemmelgarm BR Southern D Culleton BF | 2004 | Circulation2004，110，14： | 1 |
| 10 | Inferring 3D models from freehand sketches and constraints显示文摘 | Eggli L Hsu C Y Brüderlin B D | 1997 | Computer-aided Design1997，29，2： | 1 |
| 11 | Outbreak-associated Salmonella enterica serotypes and food commodities, United States, 1998 -2008显示文摘 | Jackson BR Griffin PM Cole D | 2013 | Emerg Infect Dis2013，19，8： | 1 |
| 12 | Immunofluorometric quantitation and histochemical localiaation of kallikrein 6 protein in ovarian cancer tissue: a new independent unfavourable prognostic biomarker显示文摘 | Hoffman BR Katsaros D Scorilas A | 2002 | Br J Cancer2002，87，7： | 1 |
| 13 | Choice of the adequate detection time for the accurate evaluation of the efficiency of siRNA-induced gene silencing 显示文摘 | Choi I Cho BR Kim D | 2005 | J Biotechnol2005，120，3： | 1 |
| 14 | Ameloblastin gene (AMBN) maps within the critical region for autosomal dominant amelogenesis imperfecta at chromosome 4q21 显示文摘 | DuPont BR Simmons D | 1997 | Genomics1997，41，： | 1 |
| 15 | Executive dysfunction in subcortical ischaemic vascular disease显示文摘 | Kramer JH Reed BR Mungas D | 2002 | J Neurol Neurosurg Psychiatry2002，72，2： | 1 |
| 16 | Decomposition of Populus tremuloides leaf litter accelerated by addition of Alnus crispa litter显示文摘 | Taylor BR Parsons WFJ Parkinson D | 1989 | Can J For Res1989，19，5： | 1 |
| 17 | The Bypass Angioplasty Revascularization Investigation 2 Diabetes randomized trial of different trealment strategies in type 2 diabetes mellitus with stable ischemic heart disease : impact of treatment strategy on cardiac mortality and myocardial infarction 显示文摘 | Chaitman BR Hardison RM Adler D | 2009 | Circulation2009，120，： | 1 |
| 18 | Interleukin-1 plays a major role in vascular inflammation andathero- sclerosis in male apolipoprotein E-knockout mice 显示文摘 | Merhi-Soussi F Kwak BR Magne D | 2005 | Cardiovase Res2005，66，3： | 1 |
| 19 | Recent advances in estrogen receptor modulators显示文摘 | Henke BR Heyer D | 2005 | Curr Opin Drug Discov Devel2005，8，4： | 1 |
| 20 | Removal of algal blooms in freshwater using magnetic polymer显示文摘 | Liu D Li FT Zhang BR | 2009 | Water Science and Technology2009，59，6： | 1 |
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