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| 1 | Diet,ageing and genetic factors in the pathogenesis of diverticular disease显示文摘Diverticular disease(DD) is an age-related disorder of the large bowel which may affect half of the population over the age of 65 in the UK.This high prevalence ranks it as one of the most common bowel disorders in western nations.The majority of patients remain asymptomatic but there are associated life-threatening co-morbidities, which, given the large numbers of people with DD, translates into a considerable number of deaths per annum.Despite this public health burden, relatively little seems to be known about either the mechanisms of development or causality.In the 1970s, a model of DD formulated the concept that diverticula occur as a consequence of pressureinduced damage to the colon wall amongst those with a low intake of dietary fiber.In this review, we have examined the evidence regarding the influence of ageing, diet, inflammation and genetics on DD development.We argue that the evidence supporting the barotrauma hypothesis is largely anecdotal.We have also identified several gaps in the knowledge base which need to be filled before we can complete a model for the etiology of diverticular disease. | Daniel Martin Commane Ramesh Pulendran Arasaradnam Sarah Mills John Cummings Mathers Mike Bradburn | 2009 | World Journal of Gastroenterology2009，15，20： | 5 |
| 2 | The Structure of Psychological Well - being 显示文摘 | Bradburn N M | 1969 | Chicago: Aldine Publishing Company1969，17，1： | 1 |
| 3 | An ex vivo investigation into the effects orthodontic brackets显示文摘 | Bradburn G Mclube J F Gordon P H | 1998 | Br J Orthod1998，25，： | 1 |
| 4 | 1969,The structure of Psychological well-being显示文摘 | | 1969 | Chicago:Aldine1969，，： | 1 |
| 5 | Vascμlar endothelial cell growth factor is a predictor of relapse and stage progression on superifical bladder cancer显示文摘 | Crew JP O'Brien T Bradburn M | 1997 | Br J Cancer1997，57，： | 1 |
| 6 | Old and undertriaged:a lethal combination显示文摘 | Rogers A Rogers F Bradburn E | 2012 | Am Surg2012，78，6： | 1 |
| 7 | Vascular endothelial growth factor is a predictor of relapse and stage progression in superficial bladder cancer显示文摘 | Crew JP O'Brien T Bradburn M | 1997 | Cancer Res1997，57，23： | 1 |
| 8 | Effect of thecircumferential resection margin on survival following rectal can-cer surgery显示文摘 | KELLY SB MILLS SJ BRADBURN DM | 2011 | Br J Surg2011，98，4： | 1 |
| 9 | Distribution of bone density in the proximal femur and its association with hip fracture risk in older men: the osteoporotic fractures in men (MrOS) study 显示文摘 | Yang L Burton AC Bradburn M | 2012 | J Bone Miner Res2012，27，11： | 1 |
| 10 | Detection of residual disease following breast conserving surgery显示文摘 | Beck NE Bradburn MJ Vincenti AC | 1998 | Br J Sug1998，85，9： | 1 |
| 11 | Realizations of focus invariance in optical-digital systems with wavefront coding 显示文摘 | BRADBURN S JR DOWSKI E R CATHEY W T | 1997 | Applied Optics1997，36，35： | 1 |
| 12 | Detection of residual disease following breast-conserving surgery显示文摘 | Beck NE Bradburn MJ Vincenti AC | 2005 | Br J Sug2005，85，9： | 1 |
| 13 | Statistical methods for examining heterogeneity and combining results from several studies in meta- analysis 显示文摘 | Decks J J Ahman DG Bradburn MJ | 2005 | BMJ Books2005，，： | 1 |
| 14 | Glucosinolate genetics and the attraction of the aphid parasitoid Diaeretiella rapae to Brassica显示文摘 | BRADBURNE R MITHEN R | 2000 | Proc R Soc Lond Series B2000，267，： | 1 |
| 15 | Effects of a 'new' human respiratory virus in volunteers显示文摘 | Bradburne AF Bynoe ML Tyrrell DA | 1967 | Br Med J1967，3，5568： | 1 |
| 16 | A review of dietary factors and its influence on DNA methylation in colorectal carcinogenesis显示文摘 | Arasaradnam R P Commane D M Bradburn D | 2008 | Epigenetics2008，3，4： | 1 |
| 17 | Aberration invariant optical/digital incoherent systems显示文摘 | Dowski E R Cathey W T Bradburn S C | 1996 | Optical Review1996，3，6： | 1 |
| 18 | Mesenteric Panniculitis:Review of 27 Cases显示文摘 | Ogden WW Bradburn DM Rives JD | 1965 | Ann Surg1965，161，6： | 1 |
| 19 | A comparative study of solvent extraction efficiency and the performance of immunoaffinity and solid phase columns on the determination of aflaoxin B1显示文摘 | BRADBURN N COKER R D | 1995 | Food Chemistry1995，52，： | 1 |
| 20 | Impact of surgeon volume and specialization on short term outcomes in colorectal cancer surgery显示文摘 | Borowski D W Kelly S B Bradburn D M | 2007 | Br J Surg2007，94，7： | 1 |
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