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| 1 | 重新审视中国高龄老人血压与死亡风险之间的关系:以社区为基础的纵向前瞻性队列研究显示文摘目的探讨中国高龄老人血压与3年全因死亡风险和死因别死亡风险之间的关系。研究设计以社区为基础的纵向前瞻性队列研究。研究地点2011和2014年在中国22个省份开展的两轮中国老年健康影响因素跟踪调查。研究对象4658名高龄老人(平均年龄为92.1岁)。主要结局指标随访3年全因死亡和死因别死亡。结果经过3年的随访,共计1977人死亡,收缩压(SBP)、平均动脉压(MAP)、脉压差(PP)与死亡风险间呈U型关系,SBP、MAP和PP在143.5、101和66mmHg时死亡风险最低。对混杂因素进行调整后,仅SBP与死亡风险的U型关系存在,风险最低点为129mmHg。与129mmHg的人群相比,SBP低于107mmHg时,死亡风险随SBP的升高而降低[风险比(HR)从1.47(1.01~2.17)到1.08(1.01~1.17)1;SBP高于154mmHg时,死亡风险随SBP的升高而增加[HR从1.08(1.01~1.17)到1.27(1.02~1.58)]。在死因别分析中,与中等水平SBP(107~154mmHg)相比,高水平的SBP(〉154mmHg)与心血管疾病(CVD)死亡风险升高相关联[调整HR1.51(1.12~2.02)];低水平SBP(〈107mmHg)与非CVD死亡风险升高相关联[调整HR1.58(1.26~1.98)]。在敏感性分析与亚组分析中血压与死亡风险的U型关系保持不变。结论研究在中国高龄老人中发现SBP与3年全因死亡风险呈U型关系,高SBP意味着更高的CVD死亡风险,低SBP意味着更高的非CVD死亡风险。这提示高龄老人目前的血压管理理念有待重新评估,可能需要针对这一特殊人群制定特定的血压指南。 | 吕跃斌 高翔 殷召雪 陈华帅 罗杰斯 Melanie Sereny Brasher Virginia Byers Kraus 李湉湉 曾毅 施小明 张希如(译) 毛琛(校) | 2018 | 英国医学杂志中文版2018，21，8： | 17 |
| 2 | The Status and Associated Factors of Successful Aging among Older Adults Residing in Longevity Areas in China显示文摘Objective This study aims to assess the status of successful aging(SA) in longevity areas in China and explore multiple factors associated with SA among the young-old and oldest-old. Methods A total of 2296 elderly people aged 65 and older were interviewed in the longevity areas sub-sample of the Chinese Longitudinal Healthy Longevity Survey(CLHLS) in 2012. Baseline assessments included a researcher-administered questionnaire, physical examination, and laboratory testing. A logistic regression model was used to identify factors associated with SA. Results The prevalence of SA was 38.81% in the CLHLS in 2012. There were significant differences between ages groups, with SA compromising 56.85% among ≥65 years group and 20.31% among ≥100 years group(χtrend2=126.73, P<0.01). The prevalence of SA among females was 33.59%, which was significantly lower than that among males(45.58%)(χ2gender=33.65, P<0.05). In the regression analysis, having anemia(OR=0.744, 95% CI: 0.609-0.910), poor lifestyle(OR=0.697, 95% CI: 0.568-0.854), poor sleep quality(OR=0.558, 95% CI: 0.456-0.682), and central obesity(OR=0.684, 95% CI: 0.556-0.841) were the main factors associated with SA. The promoting SA rate decreased as age increased, and the group of 65-79 years had higher odds than the other age group. Conclusion Preventing central obesity, improving sleep quality and promoting healthy lifestyle may contribute to achieve SA among the elderly. | SHI Wen Hui ZHANG Hong Yan ZHANG Juan LYU Yue Bin Melanie Sereny Brasher YIN Zhao Xue LUO Jie Si HU Dong Sheng FEN Lei SHI Xiao Ming | 2016 | Biomedical and Environmental Sciences2016，29，5： | 10 |
| 3 | 北美地区冷成型轻钢结构的应用显示文摘当前,轻钢结构在我国正在迅猛发展。但随之而来的,其相关的理论研究、施工工艺和设计标准滞后的问题也日臻突出。为此,对已成熟的北美地区轻钢结构的发展进行介绍,希望为国内相关研究借鉴。 | 刘雁 Dean Peyton Bret Brasher 王友海 | 2009 | 钢结构2009，24，3： | 3 |
| 4 | Detection of total and hemolysin-producing Vibrio parahaemolyticus in shellfish using multiplex PCR amplification of tlh, tdh and trh 显示文摘 | Bej AK Patterson DP Brasher CW | 1999 | J Microbiol Methods1999，36，3： | 1 |
| 5 | An investigation into breast support and sports bra use in female runners of the2012 London Marathon显示文摘 | Brown N White J Brasher A | 2014 | J Sports Sci2014，32，9： | 1 |
| 6 | bdluence of lithofacies and diagenesis on Norwegian North Sea chalk reservoirs显示文摘 | Brasher J E Vagle K R | 1996 | AAPG Bulletin1996，80，5： | 1 |
| 7 | Detection of total and hemolysin-producing Vibrio parahaemolyticus in shellfish using multiplex PCR amplification of tl, tdh and trh 显示文摘 | Bej A K Patterson D P Brasher C W Vickery M C L Jones D D and Kaysner C A | 1999 | Journal of Microbiological Methods1999，36，： | 1 |
| 8 | Does the new generation of high-flex knee prostheses improve the post-operative range of movement? a meta analysis显示文摘 | Mehin R Burnett RS Brasher PM | 2010 | J Bone Joint Surg Br2010，92，10： | 1 |
| 9 | Detection of total and hemolysin-producing Vibrio parahaemolyticus in shellfish using multiplex PCR amplification of fl, tdh and trh 显示文摘 | BEJ A K PATTERSON D P BRASHER C W | 1999 | J Microbiol Methods1999，36，3： | 1 |
| 10 | Information Seeking andAvoiding in Health Contexts显示文摘 | Brashers D E Goldsmith D J Hsieh E | 2002 | Human Communication Re-search2002，28，2： | 1 |
| 11 | A phase Ⅱ study of carboplatin and chronic high-dose tamoxifen in patients with recurrent malignant glioma显示文摘 | TANG P ROLDAN G BRASHER PM | 2006 | J Neurooncol2006，78，3： | 1 |
| 12 | Using inter- professional team based learning to develop health care policy显示文摘 | Rider E Brashers V Costanza M | 2008 | Medical EducaL tion2008，42，5： | 1 |
| 13 | Social support and the management of uncertainty for people living with HIV or AIDS 显示文摘 | Brashers DE Neidig JL Goldsmith DJ | 2004 | Health Commun2004，16，3： | 1 |
| 14 | Detection of total and hemolysin-producing vibrio parahaemolyticus in shellfish using multiplex PCR amplification of tl,tdh and trh显示文摘 | Patterson DP Brasher CW | 1999 | J Microbiol Methods1999，36，3： | 1 |
| 15 | Occupational stressand strain in the Royal Navy 2007 显示文摘 | BridgerRS Brasher K Dew A | 2008 | Occup Med2008，58，6： | 1 |
| 16 | A randomized trial of external beam radiotherapy versus cryoablation in patients with localized prostate cancer显示文摘 | Donnelly BJ Saliken JC Brasher PM | 2010 | Cancer2010，116，2： | 1 |
| 17 | Team-based learning: a strategy for inter- professional collaboration显示文摘 | Rider EA Brashers V | 2006 | Med Educ2006，40，5： | 1 |
| 18 | Pharmacological prevention of sevoflurane-and desflurane-related emergence agitation in children:a meta-analysis of published studies显示文摘 | Dahmani S Stany I Brasher C | 2010 | Br J Anaesth2010，104，2： | 1 |
| 19 | Using interprofessional team-based learning to develop health care policy 显示文摘 | Rider EA Brashers VL Costanza ME | 2008 | Med Educ2008，42，5： | 1 |
| 20 | The medical consulation its role in dentistry显示文摘 | Brasher W J | 1997 | J Am Dent Assoo1997，95，： | 1 |
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