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| 1 | Aloesin as a medical food ingredient for systemic oxidative stress of diabetes显示文摘Diabetes is a chronic disease that requires a long term management where oxidative stress plays a pivotal role in disease progression and intensifying secondary complications. In spite of all the research on diabetes and recent advances in diabetes treatments, the reality is that there is no cure for diabetes and its devastating complications. While currently available anti-diabetic therapies are effective in reducing blood glucose level, they are not without associated side effects when they are used for a long term applications. As a result, physicians and patients are inclining more towards to a safer therapy with less serious side effects in the form of medicinal foods and botanical alternatives that are suitable for chronic usage. Aloesin, an Aloe chromone, has previously been formulated with an aloe polysaccharide to give a composition called Loesyn, where it showed significant impact in reducing glycosylated hemoglobin, fasting blood glucose, fructosamine and plasma insulin level in humans. Radical scavenging activities of chromones and polysaccharides from Aloe have also been reported. Here we rationalize the relevance of use of Aloesin alone or in a standardized blend with Aloe polysaccharides, as a potential medical food to manage systemic oxidative stress and/or high blood glucose of diabetes. | Mesfin Yimam Lidia Brownell Qi Jia | 2015 | World Journal of Diabetes2015,6,9: | 9 |
| 2 | Micro- and nanomeehanics of the cochlear outer hair cell显示文摘 | Brownell WE Spector AA Raphael RM | 2001 | Ann Rev Biomed Eng2001,3,: | 1 |
| 3 | Gap junction communication in cultured human lung carcinoma cells显示文摘 | Tomai E Brownell H L Tufescu T V | 1999 | Lung1999,23,3: | 1 |
| 4 | Deposition of particles on rough surfaces during turbulent gas-flow in pipe显示文摘 | BROWNEL W B | 1974 | Atmospheric Environment1974,8,: | 1 |
| 5 | Micro- and nanomechanics of the cochlear outer hair cell显示文摘 | BROWNELL W E SPECTOR A A RAPHAEL R M | 2001 | Annu Rev Biomed Eng2001,3,: | 1 |
| 6 | Detection of dopaminergic activity using pharmacologic MRI: correlation with PET, microdialysis, and behavioral data显示文摘 | Chen YC Galpern WR Brownell AL | 1997 | Magn Reson Med1997,38,3: | 1 |
| 7 | Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease显示文摘 | McNaught KS Perl DP Brownell AL | 2004 | Ann Neurol2004,56,1: | 1 |
| 8 | Self-concept in obese and normal-weight children 显示文摘 | Wadden TA Forster GD Brownell KD | 1984 | J Cons Clin Psychol1984,52,: | 1 |
| 9 | The role of budgets in organizations being strategic change:an exploratory study显示文摘 | Abemethy M A Brownell P | 1999 | Accotinting Organizations and Society1999,,3: | 1 |
| 10 | The require- ment for micronutrient by species having the C4 di- carboxylic photosynthes is pathway显示文摘 | BROWNELL P F CROSSLAND C J | 1972 | Plant1972,49,5: | 1 |
| 11 | Meeting the competency needs of global leaders: a Partnership approach 显示文摘 | Brownell J | 2006 | Human Resource Management2006,45,3: | 1 |
| 12 | Systemic exposure toproteasome inhibitors causes a progressive model of Parkinson’sdisease显示文摘 | McNaught KS Perl DP Brownell AL | 2004 | Ann Neurol2004,56,1: | 1 |
| 13 | The getting of wisdom : theory of mind in old age 显示文摘 | Happe FGE Winner E Brownell H | 1998 | Developmental Psychol1998,34,2: | 1 |
| 14 | Etiology and treatment of obesity:Understanding a serious, prevalent, and refractory disorder显示文摘 | Brownell K D Wadden T A | 1992 | Journal of Consulting and Clinical psychology1992,60,: | 1 |
| 15 | Administrative Record Linkage as a Tool for Public Health Research显示文摘 | Douglas P. Jutte Leslie L. Roos Marni D. Brownell | 2011 | Annual Review of Public Health2011,,: | 1 |
| 16 | Mapping dopamine function in primates using pharmacologic magnetic resonance imaging显示文摘 | Jenkins B G Sanchez-Pernaute R Brownell A L Chen Y C Isacson O | | 0,,43: | 1 |
| 17 | Increased carbonic anhydrase activity in leaves of sodium-deficient C4 plants显示文摘 | Brownell PF Bielig LM Grof CPL | 1991 | Aust J Plant Physiol1991,,18: | 1 |
| 18 | Field test and cost analysis of four harvesting options for herbaceous biomass handling显示文摘The nature of most biomass materials is a low bulk density as compared to traditional fuel sources.High handling cost could be a limiting factor in utilizing biomass feedstock.Understanding available harvesting machinery systems and associated costs is critical to future implementation.Four popular harvesting machinery systems were studied and costs were analyzed based on field measurements and calculations.These four systems included(1)round baling and round bale handling systems,(2)large square baling and square bale handling systems,(3)forage harvester and trucking systems,and(4)large square baling plus square bale compression systems.Results indicated that a self-loading forage wagon can reduce the cost to harvest a crop but requires more harvest time.Large square bales were found to reduce cost of handling and transport as compared to round bales.Further research is needed to determine storage costs and deterioration loss of the two bale types.Compressed square bales were found to reduce storage,handling and transport costs.Compressed bale machinery has a high initial cost,which currently makes only valuable for hay export. | Douglas Brownell Jude Liu | 2011 | International Journal of Agricultural and Biological Engineering2011,4,3: | 1 |
| 19 | 显示文摘 | Brownell H H | 1986 | Biotechnology Bioengineering1986,28,6: | 1 |
| 20 | Celastrol induces unfolded protein response-dependent cell death in head and neck cancer显示文摘 | Fribley A M Miller J R Brownell A L | 2014 | Exp Cell Res2014,330,2: | 1 |