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373篇 您的检索式:作者名="Bruce R D"
    题名 作者 年代 出处 被引量
1Hematopoietic AMPK [Beta]1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity显示文摘Galic Sandra Fullerton Morgan D Schertzer Jonathan D Sikkema Sarah Marcinko Katarina Walkley Carl R Izon David Honeyman Jane Chen Zhi-Ping van Denderen Bryce J Kemp Bruce E Steinberg Gregory R 2011Journal of Clinical Investigation2011,,12:2
2β内酰胺类抗生素与对非典型病原体有效的抗生素在非重症社区获得性肺炎中的疗效比较:汇总分析显示文摘目的对于社区获得性肺炎,将β内酰胺类抗生素与对非典型病原体有效的抗生素进行全面系统的疗效比较。资料来源Medline、Embase、Cochrane登记注册的对照试验、国际性会议的会议纪录、药品注册机构以及制药公司。评价方法通过总结双盲、随机、对照、单一给药疗法试验,对β内酰胺类抗生素与对非典型病原体有效的抗生素在成人社区获得性肺炎的疗效方面进行比较。主要结局指标是未达到临床治愈或好转。结果18项临床试验共纳入6749例受试者,其中大多数患者有轻至中度社区获得性肺炎。对各种原因引起的社区获得性肺炎治疗失败的相对危险度进行分析,结果显示对非典型病原体有效的抗生素并不优于β内酰胺类抗生素(0.97,95%可信区间0.87~1.07)。对于有特异性非典型病原体感染诊断的患者进行亚组分析,我们发现应用对非典型病原体有效的抗生素治疗军团菌属感染的肺炎患者,其治疗无效率明显的低一些(0.40,0.19~0.85)。而在肺炎支原体(0.60,0.31~1.17)和肺炎衣原体(2.32,0.67~8.03)感染的肺炎患者中二者的疗效相似。结论应用对非典型病原体有效的抗生素治疗由各种原因引起的非重症社区获得性肺炎,而使临床疗效得到提高的证据是不足的。尽管此类抗生素在对稍后介绍的军团菌感染相关性肺炎的治疗方面显示出明显的优势,但已纳入研究范围内的肺炎病例很少是由这种病原体引起的。β内酰胺类制剂应该继续作为成人非重症社ResInfe区获得性肺炎治疗的首选抗生素。Graham D Mills Michael R Oehley Bruce Arrol 刘艳(译) 代华平(校) 2005英国医学杂志中文版2005,8,4:2
3The tibial plateau fracture:the Toronto experience 1968 -1975 显示文摘Schatzker J McBroom R Bruce D 1979Clin Orthop1979,,138:1
4The tibial plateau fracture:the toronto experience 1968-1975显示文摘Schatzker J McBroom R Bruce D 1979Clin Orthop1979,138,2:1
5The tibial plateau fracture: the Toronto experience 1968-1975 显示文摘Schatzker J McBroom R Bruce D 1979Clin Orthop1979,138,:1
6The tibial plateau fracture the Toronto experience 1968-1975显示文摘SchatzkerJ Mcbroom R Bruce D 1979Clin Orthop1979,13,8:1
7Bioassays for allelopathy:Measuring treatment responses with independet controls显示文摘Williamson G Bruce D R 0,,01:1
8Power and machinery: seed loss when cutting a standing crop of oilseed rape with two types of combine harvester header 显示文摘Hobson R N Bruce D M 2002Biosystems Engineering2002,81,3:1
9Protein identification with a single accurate mass of a cysteine-containing peptide and constrained database searching显示文摘 Bruce J E Anderson G A 2000Anal Chem2000,72,:1
10The tibial plateau fractures显示文摘Schatzker J McBroom R Bruce D 1979Clin Orthop Relat Res1979,138,:1
11Effect of textile properties in evalu- ating a directional shading fabric 显示文摘MAUREEN M G BRUCE D H ARDIS M R 1997Textile Research Journal1997,67,4:1
12Observations on the use of rigid fixation for craniofacial deformities in infants and young children显示文摘Fearon J A Munro I R Bruce D A 1995Plast Reconstr Surg1995,5,4:1
13PPARγ: A nuclear regulator of metabolism, differentiation, and cell growth显示文摘Evan D R Bruce M S 2001J Biol Chem2001,276,37:1
14The tibial plateau fracture: the Toronto experience 1968 - 1975 显示文摘Schatzker J McBroon R Bruce D 1979Clin Orthop Relat Res1979,,138:1
15查看详情显示文摘P Metrangolo C Prasang G Resnati R Liantonio A C Whitwood D W Bruce 0,,:1
16Aqueous film coating to reduce recrystallization of guaifenesin from hot-melt extruded acrylic matrices 显示文摘BRUCE C D FEGELY K A RAJABI A R 2010Drug Dev Ind Pharm2010,36,2:1
17Wind-tunnel and field investigation of the effect of local wind direction on speed-up over hills显示文摘LUBIZ W D BRUCE R W 2007Journal of Wind Engineering and Industrial Aerodynamics2007,95,:1
18A first linkage map of pe-can cultivars based on RAPD and AFLP markers显示文摘Sudheer R B Sue K D Bruce W W 0,,06:1
19The tibial plateau fracture: The Toronto experience 1968-1975显示文摘Schatzker J Mc Broom R Bruce D 1979Clin Orthop1979,138,:1
20Magnetic ionexchange resin treatment: Impact of water type and resin use 显示文摘Max R D Mergen Bruce Jefferson Simon A 2008Water Research2008,42,89:1
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