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419篇 您的检索式:作者名="CABRAL J"
    题名 作者 年代 出处 被引量
1Response evaluation of chemotherapy in metastatic colorectal cancer by contrast enhanced ultrasound显示文摘AIM:To evaluate whether contrast enhanced ultrasound(CEUS) might also be used for response prediction and early response evaluation in patients receiving bevacizumab based chemotherapy for metastasized colorectal cancer.METHODS:Thirty consecutive patients with non primary resectable liver metastases from colorectal cancer underwent CEUS before treatment(CEUS date 1) and before the second(CEUS date 2) and fourth(CEUS date 3) cycle of bevacizumab based chemotherapy.Three parameters [PEAK,Time to peak(TTP) and RISE RATE]were correlated with radiological response.RESULTS:For neoadjuvant purpose a reduction of tumour mass was required to assume clinical response.Based on these response criteria there was a significant(P < 0.001) correlation in TTP between metastases of responders(9.08 s) and non-responders(14.76 s) archived on CEUS date 1.By calculating a standardized quotient(metastases divided by normal liver tissue) we were able to define a cut off,predicting response with a sensitivity of 92.3 % and a specificity of 100 %.To reflect a palliative intention only those patients with progressive disease were classified as non-responders.In this stetting TTP was also significantly(P < 0.01) different between responders and non-responders.In contrast,Peak and Rise rate did not show any significant difference between responder and non-responder.CONCLUSION:CEUS might serve as a surrogate marker to predict treatment response in patients with metastasized colorectal cancer who receive antiangiogenic therapy.Ramin Schirin-Sokhan Ron Winograd Christoph Roderburg Jhenee Bubenzer Nicole Cabral do ó Dorothee Guggenberger Hartmut Hecker Christian Trautwein Jens J W Tischendorf 2012World Journal of Gastroenterology2012,18,6:16
2中等收入国家年轻人脑卒中发病率增加:基于10年人口的研究显示文摘高收入国家年轻人脑卒中的发病率正在上升。然而,低收入和中等收入国家年轻人的脑卒中发病趋势仍未知。该研究旨在分析2005—2015年在巴西Joinville的年轻人的缺血性脑卒中(isehemic stroke,IS)和脑出血的发病趋势。刘莉 叶鹏 Cabral NL Freire AT Conforto AB Dos Santos N Reis FI Nagel V Guesser VV Safanelli J Longo AL 2017中华高血压杂志2017,25,11:6
3Exercise training on disease control and quality of life in asthmatic children显示文摘FANELLI A CABRAL A L NEDER J A 2007Med Sci Sports Exerc2007,39,:1
4Down-regulation of factor IXa in thefactor Xase complex by protein Z-dependent protease inhibitor显示文摘Heeb M J Cabral K M Ruan L 2005JBiol Chem2005,280,33:1
5The structure of the potassium channel :Molecular basis of K conduction and selectivity显示文摘Doyle DA Morais Cabral J Pfuetzner RA 1998Science1998,280,:1
6Intra-Industry Trade Expansion and Employment Reallocation between Sectors and Occupa- tions 显示文摘CABRAL M SILVA J 2006Review of World Economics2006,,3:1
7The influence of cul-ture conditions on mycelial structure and eellulase production by Trichoderma reese/Rut C-30显示文摘Domingues F C Queiroz J A Cabral J M S 2000Enzyme and Microbial Technolo-gy2000,26,5:1
8The effects of nutrient losses from agriculture on ground and surface water quality:The position of science in developing indicators for regulation显示文摘Scroder J J Scholefield D Cabral F 2004Environmental Science & Policy2004,7,:1
9Phytosterols : Applications and recovery methods 显示文摘Fernandes P Cabral J M S 2007Bioresource Technology2007,98,12:1
10Monopoly Pricing with Network Externalities 显示文摘Cabral L M B Salant D J Woroch G A 1999International Journal of Industrial Organization1999,17,2:1
11Phytosterols: applications and recovery methods 显示文摘FERNANDES P CABRAL J M 2007Bioresource Technology2007,98,12:1
12A comparison of proper orthngonal decomposition and Mote Carlo simulation of wind pressure data显示文摘Rocha M M Cabral S V S Riera J D 2000Journal of Wind Engineering Industrial Aerodynamics2000,84,:1
13Rheumatic manifestations of Bartonella infection in 2 children 显示文摘Al-Matar M J Petty R E Cabral D A 2002J Rheumatol2002,29,:1
14Behavior of tire shred-soil mixtures显示文摘ZORNBERG J G CABRAL A VIRATJANDR C 2004Canadian Geotechnical Journal2004,41,2:1
15Trophic structure of macrobenthos in the Tagus estuary and adjacent coastal shelf 显示文摘Gaudencio M J Cabral H N 2007Hydrobiologia2007,587,1:1
16Immobilization studies of an industrial penicillin acylase preparation on a silica carrier 显示文摘FONSECA L P CARDOSO J P CABRAL J M S 1993J Chem Technol Biotechnol1993,58,1:1
17Bulk Spinodal Decomposition Studied by Atomic Force Microscopy and Light Scattering显示文摘Cabral J T Higgins J S 2001Macromolecules2001,34,:1
18Randriamahefa catalysis of the specific michael addition: the example of acrylate acceptors 显示文摘Cabral J Laszlo P Montaufier S L 1989Tetrahedron Lett1989,30,:1
19Modeling mosquitofish (Gambusia holbrooki) responses to Genapol OXD-080, a non-ionic surfactant, in rice fields显示文摘Cabral J A Marques J C Nielsen S N 2001Ecological Engineering2001,16,4:1
20Autoimmunity inflammation from theTh17perspective显示文摘FURUZAWA-CARBALLEDA J VARGAS-ROJAS MI CABRAL A R 2007Autoimmun Rev2007,6,:1
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