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223篇 您的检索式:作者名="CONNELLY C"
    题名 作者 年代 出处 被引量
1Mouse embryos cloned from brain tumors显示文摘Cancer cells escape from growth cont rol by accumulating genetic and epig enetic alterations.In rare instances,epigenetic changes alone are oncogenic.Furthermore,a gents that modify DNA methylation or chromatin structure can restore a normal phenotype to cells harboring oncogenic mutations.How ever,it is unclear to what extent epi genetic reprogramming can reverse o ncogenesis.Using somatic nuclear transfer,we show that medul loblastomas arising in Ptc1+/-mice can direct preimplantation develop ment.Additionally,blastocysts derived from medullobl astoma nuclei form postimplantatio n embryos with typical cell layers.T hus,tumor cells can be epigenetically reprogrammed into n ormal cell types.This approach coul d lead to a general strategy for assessing genetic and epigenetic contributions to tumorigenesis.Li L Connelly MC Wetmore C Curran T Morgan JI 2003癌症2003,22,7:11
2Predictors of Employees′ Perceptions of Knowledge Sharing Cultures显示文摘Connelly C E Kelloway E K 2009Leadership & Organization Development Journal2009,24,6:1
3Multiwavelength activelymode-locked fiber ring laser with a dispersion compensatedcavity 显示文摘O’Riordan C Connelly M J 2010Optics Communications2010,283,9:1
4Metabonomics: a platform for studying drug toxicity and gene function显示文摘Nicholson J K Connelly J Lindon J C 2002Nat Rev Drug Discov2002,1,2:1
5Metabolic activity of cultured rat brainstem,hippocampal and spinal cord slices显示文摘Carroline A Connelly Lawrence C 2000J Neurosci Methods2000,99,:1
6Metabonomics:a platform for studying drug toxicity and gene function显示文摘Nicholson J K Connelly J Lindon J C 2002Nat Rev Drug Discov2002,1,2:1
7Metabonomics:a platform for studying drug toxicity and gene function显示文摘NICHOLSON J K CONNELLY J LINDON J C 0,,:1
8Soot formation in laminar diffusion flames 显示文摘Smooke M D Long M B Connelly B C 2005Combustion and Flame2005,143,4:1
9Soot Formation in Laminar Diffusion Flames 显示文摘Smooke M D Long M B Connelly B C 2005Combustion and Flame2005,143,:1
10Composition-structure Relationships in Simplified Nuclear Waste Glasses:Mixed Alkali Borosilicate Glasses显示文摘Connelly A J Travis K P Hyatt N C 2011Journal of the American Ceramic Soeiety2011,94,1:1
11Delivery of adenoviral DNA to mouse liver显示文摘Connelly S Mech C 2004Methods Mol Biol2004,246,:1
12A noise-based IC random number generator for applications in cryptography 显示文摘Petrie C S Connelly J A 2000IEEE Transactions on Circuits and Systems I: Fundamental Theory and Applications2000,47,5:1
13Cost - effective knowledge sharing strategies 显示文摘CONNELLY C E 2002KM Review2002,5,4:1
14EGFR-dependent downregulation of Bim in epithelial cells requires MAPK and PKC-δ activities显示文摘Quadros MR Connelly S Kari C Abrams MT Wickstrom E Rodeck U 0,,05:1
15Metabonomics:a platform for studying drug toxicity and gene function显示文摘Nicholson J K Connelly J Lindon J C 2002Nat Rev Drug Discov2002,1,2:1
16Invention and innovation: A case study in metals显示文摘CONNELLY M C SEKHAR J A 2008Key Engineering Materials2008,380,:1
17Emerging trends in contingent work research显示文摘Connelly C E Gallagher D G 2004Journal of Management2004,30,6:1
18Meta-bonomics: a platform for studying drug toxicity and gene function 显示文摘NICHOLSON J K CONNELLY J LINDON J C 2002Nat Rev Drug Discov2002,1,2:1
19MRP4: A previously unidentified factor in resistance to nucleoside - based antiviral drugs显示文摘Schuetz J D Connelly M C Sun D 1999Nat Med1999,5,:1
20Sensors and technologies for in situ dissolved methane measurements and their evaluation using technology readiness levels显示文摘Boulart C Connelly D P Mowlem M C 2010Trends in Analytical Chemistry2010,29,2:1
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