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| 1 | Metabolic syndrome and colorectal neoplasms:An ominous association显示文摘AIM:To evaluate the association of metabolic syndrome(MS) and colorectal cancer and adenomas in a Western country,where the incidence of MS is over 27%.METHODS:This was a prospective study between March 2013 and March 2014.MS was diagnosed according to the National Cholesterol Education ProgramATP III.Demographic characteristics,anthropometric measurements,metabolic risk factors,and colonoscopic pathologic findings were assessed in patients with MS(group 1) who underwent routine colonoscopy at our department.This data was compared with consecutive patients without metabolic syndrome(group 2),with no differences regarding sex and age.Patients with incomplete colonoscopy,family history,or past history of colorectal neoplasm were excluded.Informed consent was obtained and the ethics committee approved this study.Statistical analysis was performed using Student's t-test and χ2 test,with a P value ≤ 0.05 being considered statistically significant.RESULTS:Of 258 patients,129 had MS;51% males;mean-age 67.1 years(50-87).Among the MS group,94% had high blood pressure,91% had increased waist circumference,60% had diabetes,55% had low high-density lipoprotein cholesterol level,50% had increased triglyceride level,and 54% were obese [body mass index(BMI) 30 kg/m2].51% presented 4 criteria of MS.MS was associated with increased prevalence of adenomas(43% vs 25%,P = 0.004) and colorectal cancer(13% vs 5%,P = 0.027),compared with patients without MS.MS was also positively associated with multiple(≥ 3) adenomas(35% vs 9%,P = 0.024) and sessile adenomas(69% vs 53%,P = 0.05).No difference existed between location(P = 0.086),grade of dysplasia(P = 0.196),or size(P= 0.841) of adenomas.In addition,no difference was found between BMI(P = 0.078),smoking(P = 0.146),alcohol consumption(P = 0.231),and the presence of adenomas.CONCLUSION:MS is positively associated with adenomas and colorectal cancer.However,there is not enough information in western European countries to justify screening in patients with MS.To our knowledge,no previous study has evaluated this association in Portuguese patients. | Daniel Trabulo Suzane Ribeiro Cláudio Martins Cristina Teixeira Cláudia Cardoso Jo?o Mangualde Ricardo Freire élia Gamito Ana L Alves Fátima Augusto Ana P Oliveira Isabelle Cremers | 2015 | World Journal of Gastroenterology2015，21，17： | 5 |
| 2 | Profile of microbial communities present in tibico(sugary kefir)grains from different Brazilian States显示文摘 | da CP MIGUEL M G CARDOSO P G MAGALHES K T | 2011 | World Journal of Microbiology and Biotechnology2011，27，8： | 1 |
| 3 | Preparation of activated carbons from cork waste by chemical activation with KOH显示文摘 | Carbalho P A Cardoso B P Pires J | 2003 | Carbon2003，41，14： | 1 |
| 4 | 显示文摘 | Carbalho P A Cardoso B P | 2003 | Carbon2003，41，14： | 1 |
| 5 | Extraction and re- extraction of phenylalanine by cationic reversed micelles in hollow fibre contactors显示文摘 | CARDOSO M M VIEGAS R M C CRESPO J P S G | 1999 | Journal of Membrane Scince1999，156，2： | 1 |
| 6 | Subspace methods for the blind identification of multi-channel FIR filters 显示文摘 | Moulines E Duhamel P Cardoso J | 1995 | IEEE Transactions on Signal Processing1995，43，2： | 1 |
| 7 | Reliable eighteenhour lung preservation at 4 degrees and 10 degrees by pulmonary artery flush after high-dose prostaglandin E1 administration显示文摘 | Mayer E Puskas J D Cardoso P F | 1992 | J Thorac Cardiovasc Surg1992，103，： | 1 |
| 8 | Scalar, electromagnetic, and Weyl perturbations of BTZ black holes: Quasinormal modes显示文摘 | CARDOSO V LEMOS J P S | 2001 | Phys Rev D2001，63，12： | 1 |
| 9 | Quality of service for workflows and Web service processes显示文摘 | CARDOSO J SHETH A P MILLER J A | 2004 | Web Semantics2004，1，3： | 1 |
| 10 | New tools for assessing breast cancer recurrence 显示文摘 | Dinh P Cardoso F Sotiriou C | 2008 | Cancer Treat Res2008，141，： | 1 |
| 11 | Release from quiescence of CD34+CD38- human umbilical xord blood cells reveals their potentiality to engraft adults显示文摘 | Cardoso A Li M-L Batard P | 1993 | Proc Natl Acad Sci USA1993，90，： | 1 |
| 12 | Design and planning of supply chains with integration of reverse logistics activities under demand uncertainty 显示文摘 | Cardoso S R Barbosa-Povoa A P F D Relvas S | 2013 | European Journal of Operational Re- search2013，226，： | 1 |
| 13 | Subspace methods for the blind identification of multichannel FIR filters显示文摘 | Moulines E Duhannel P Cardoso J F | 1995 | IEEE Trans on Signal Processing1995，43，2： | 1 |
| 14 | Quantitative study of caspase-3 activity in semen and after swim-up preparation in relation to sperm quality显示文摘 | Almeida C Cardoso MF Sousa M Viana P Gon(c)alves A Silva J | 2005 | Hum Reprod2005，20，5： | 1 |
| 15 | Prevalence of musculoskeletal pain among teachers显示文摘 | Cardoso J P Ribeiro I Q B Araújo T M | 2009 | Revista Brasileira de Epidemiologia2009，，04： | 1 |
| 16 | Cell cy- cle markers for live cell analyses 显示文摘 | Easwaran H P Leonhardt H Cardoso M C | 2005 | Cell Cycle2005，4，3： | 1 |
| 17 | Spinal and sacroiliac gouty arthritis: report of a case and review of the literature 显示文摘 | Cardoso FN Omoumi P Wieers G | 2014 | Acta Radiol Short Rep2014，3，8： | 1 |
| 18 | A sharp lower bound for the least eigenvalue of the signless Laplacian of a non-bipartite graph显示文摘 | Cardoso D M Cretkovic D M Rowlinson P | 2008 | Linear Algebra Appl2008，429，： | 1 |
| 19 | Immobilization studies of an industrial penicillin acylase preparation on a silica carrier 显示文摘 | FONSECA L P CARDOSO J P CABRAL J M S | 1993 | J Chem Technol Biotechnol1993，58，1： | 1 |
| 20 | Nutritional requirement of digestible tryptophan for white-egg layers of 60 to 76 weeks of age 显示文摘 | CARDOSO A S COSTA F G P DA SILVA J H V | 2014 | The Journal of Applied Poultry Research2014，23，4： | 1 |
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