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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | Modeling and control of magnetorheological dampers forseismic response reduction 显示文摘 | DYKE S J SPENCER B F SAIN M K CARLSON J D | 1996 | Smart Materials and Structures1996，5，5： | 2 |
| 3 | Mental retardation and relation to seizure and tuber burden in tuberous sclerosls eotnplex 显示文摘 | Zaroff CM Barr WB Carlson C LaJoie J Madhavan D Miles DK | 2006 | Seizure2006，15，7： | 1 |
| 4 | Effects of three harvest schedules on forage yield, quality, and persistence of six alfalfa cultivars显示文摘 | Carlson I T Obierika I D C | 1981 | Agricultural Reviews and Manuals1981，19，： | 1 |
| 5 | Disparity mapping applied to sonography of the breast 显示文摘 | Steinberg B D Sullivan D C Carlson D L | 1998 | Radiology1998，207，2： | 1 |
| 6 | Covariance matrix estimation errors and diag- onal loading in adaptive arrays 显示文摘 | Carlson B D | 1988 | IEEE Transactions on Aerospace and Electronic systems1988，24，4： | 1 |
| 7 | Construction and validation of a multidimensional measure of work-family conflict显示文摘 | Carlson D S Kacmar L J | 2000 | J Vocat Behav2000，56，2： | 1 |
| 8 | Radar detection in multipath显示文摘 | Wilson S L and Carlson B D | 1999 | IEE Proceedings of Radar Sonar and Navigation1999，146，1： | 1 |
| 9 | Sentinel lymph node biopsy for breast cancer: a suitable alternative to routine axillary dissection in multi-inatitutional practice when optimal technique is used显示文摘 | MCMASTERS K M TUTTLE T M CARLSON D J | 2000 | J Clin Oncel2000，18，13： | 1 |
| 10 | Floc morphology and cyclic sheafing recovery: comparison of alum and polyaluminum chloride coagulants 显示文摘 | McCurdy K Carlson K Gregory D | 2004 | Water Research2004，38，2： | 1 |
| 11 | RH-5849, a nonsteroidal ecdysone agonist: effects on larval lepidoptera 显示文摘 | K D Wing R A Slawecki G R Carlson | 1988 | Science1988，241，： | 1 |
| 12 | Evidence that physiLologic levels of circulating estrogens and neonatal sex-imprinting modify postpubertal hepatic microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase acivity显示文摘 | Carlson S E Mitchell A D Carter M L | 1980 | Biochem Biophys Acta1980，633，： | 1 |
| 13 | Dvelopment and testing of a clinical tool measuring self-management of heart failure显示文摘 | Riegel B Carlson B Glaser D | 2000 | Heart Lung2000，29，1： | 1 |
| 14 | Starlike and prestarlike hypergeometric functions显示文摘 | Carlson B C Sharer D B | 1984 | SIAM J Math Anal1984，15，： | 1 |
| 15 | Variability of apatite fission track annealing kinetics III: extrapolation to geological time scales 显示文摘 | Ketcham R A Donelick R A Carlson W D | 1999 | American Mineralogist1999，84，9： | 1 |
| 16 | Biochemical and molecular characterization of a mutation that confers a decreased raffinosaccharide and phytic acid phenotype on soybean seeds 显示文摘 | Hize W D Carlson T J Kerr P S Sebastian S A | 2002 | Plant Physiology2002，128，： | 1 |
| 17 | On the relation between NDVI, fractional vegetation cover, and leaf area index 显示文摘 | Carlson T N Ripley D A | 1997 | Remote Sensing of Environment1997，62，03： | 1 |
| 18 | The Reaction of a Phosphorus Ylide with Aroyl Cyanides显示文摘 | Soulen R L Carlson S D Lang F | 1973 | J Org Chem1973，38，3： | 1 |
| 19 | Development of new feeding-distance rules using casting simulation: part II, the new rules 显示文摘 | Ou S Carlson K D Hardin R A | 2002 | Metallurgical and Materials Transactions B2002，33，： | 1 |
| 20 | SNPing in thehuman genome显示文摘 | CARLSON CS NEWMAN TL NICKERSON D | 2001 | Curr Opin Chem Biol2001，5，1： | 1 |
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