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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | 华南栖霞组菊花石假象内正延性玉髓的成因及其地质意义显示文摘正延性玉髓常被视为干旱蒸发沉积环境的标志。正延性玉髓亦广泛分布于华南地区栖霞组菊花石 (目前绝大多数为天青石假象 )内。本文在天青石后期矿物交代序列识别的基础上 ,通过对菊花石内各期次碳酸盐交代矿物的电子探针分析 ,发现菊花石内正延性玉髓形成于富含硫酸根离子和镁离子的成岩介质条件中。结合已有的正延性玉髓研究报道和栖霞组的沉积、成岩作用环境特征分析 ,认为华南地区栖霞组菊花石内正延性玉髓的形成环境与高蒸发沉积环境或高盐度成岩环境无关。因此 。 | 颜佳新 夏琼霞 E H Carlson | 2001 | 沉积学报2001，19，3： | 3 |
| 3 | Reversible middle cerebral artery occlusion without craniectomy in rats显示文摘 | Longa E Z WeinsteinP R Carlson S | 1989 | stroke1989，20，1： | 2 |
| 4 | Performance of ILU preconditioning techniques in simulating anisotropic diffusion in the human brain显示文摘 | Kang N Zhang J Carlson E S | 2004 | Future Generation Computer Systems2004，20，4： | 2 |
| 5 | Reversible middle cerebral artery occlusion without craniectomy in rats显示文摘 | Longa E Z Weinstein P R Carlson S | 1989 | Stroke1989，20，1： | 2 |
| 6 | A trophic sate index for lakes 显示文摘 | CARLSON R E | 1997 | Limnol Ocean1997，22，： | 1 |
| 7 | Rhgl alleles from soybean PI 437654 and PI 88788 respond differentially to isolates of Heterodera glycines in the greenhouse 显示文摘 | Brucker E Carlson S Wright E | 2005 | Theor Appl Genet2005，111，1： | 1 |
| 8 | Perturbative QCD calculations of heavy meson exlusive decays显示文摘 | Milana J | 1993 | Phys lett1993，301，： | 1 |
| 9 | Remote Estimation of Sell Moisture Availability and Fractional Vegetation Cover for Agricultural Fields显示文摘 | Perry E M Schmugge T J | 1990 | Agriculture and Forest Meteorology1990，52，12： | 1 |
| 10 | A randomized,wait-list controlled clinical trial:The effect of a mindfulness meditation-based stress reduction program on mood and symptoms of stress in cancer outpatients显示文摘 | Speca M Carlson LE Goodey E | 2000 | Psychosomat Med2000，62，5： | 1 |
| 11 | Reversible middle cerebral artery occlusion without craniectomy in rats显示文摘 | Zea Longa E L Weinstein P R Carlson S | 1989 | Stroke1989，20，1： | 1 |
| 12 | Reversible middle cerebral artery occlousion without cranieclomy in rats显示文摘 | Zea Longa E Weinstein P R Carlson S | 1989 | Stroke1989，20，： | 1 |
| 13 | Reversible middle cerebral artery occlusion without craniectomy in rats显示文摘 | Longa E Z Weinstein P R Carlson S Cummins R | 1989 | Stroke1989，20，1： | 1 |
| 14 | Reversible middlecerebral artery occlusion without craniectomy in rats 显示文摘 | Zea Longa E L Weinstein P R Carlson S | 1989 | Stroke1989，20，1： | 1 |
| 15 | Reversible middlecerebral artery occlusion without eraniectomy in rats 显示文摘 | LONGA Z E WEISTEIN P R CARLSON S | 1989 | Stroke1989，20，： | 1 |
| 16 | Reversible middle cere-bral artery occlusion without craniectomy in rats 显示文摘 | Longa E Z Weinstein P R Carlson S | 1989 | Stroke1989，20，1： | 1 |
| 17 | A dominant repression domain in Tbx3 mediates transcriptional repression and cell immortalization: relevance to mutations in Tbx3 that cause ulnar-mammary syndrome显示文摘 | Carlson H Ota S Campbell C E | 2001 | Hum Mol Genet2001，10，21： | 1 |
| 18 | Evidence that physiLologic levels of circulating estrogens and neonatal sex-imprinting modify postpubertal hepatic microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase acivity显示文摘 | Carlson S E Mitchell A D Carter M L | 1980 | Biochem Biophys Acta1980，633，： | 1 |
| 19 | Reversible middle cerebral artery occlusion without craniectomy in rats显示文摘 | ZEALONGA E WEINSTEIN PR CARLSON S | 1989 | Stroke1989，20，1： | 1 |
| 20 | Skeletal muscle myostatin mRNA expression is fiber-type specific and increases during hindlimb unloading 显示文摘 | CARLSON C J BOOTH F W GORDON S E | 1999 | Am J Physiol1999，277，： | 1 |
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