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| 1 | 对于室间隔缺损合并肺动脉闭锁的患儿,与死亡、再次手术和获得完全修复相关的独立因素显示文摘OBJECTIVES:We described morphologic characteristics, particularly pulmonary an atomy, and determined the prevalence of definitive end states and their determin ants in children with pulmonary atresia associated with ventricular septal defec t(PAVSD). BACKGROUND: Pulmonary atresia associated with ventricular septal defec t represents a broad morphologic spectrum that greatly influences management and outcomes. METHODS: From 1975 to 2004, 220 children with PAVSD presented to our institution. Blinded angiographic review(n=171) characterized bronchopulmonary s egment arterial supply. RESULTS:A total of 185 patients underwent surgery,and re pair was definitive in 75%. Initial operations included systemic-pulmonary art ery shunt in 57%, complete primary repair in 31%, or right ventricular outflow tract reconstruction in 12%. Based on angiographic review,118 patients had sim ple PAVSD and 53 patients had PAVSD with major aortopulmonary collateral arterie s(MAPCAs). Overall survival from initial operation was 71%at 10 years. Risk fac tors for death after initial operation included younger age at repair, earlier b irth cohort, fewer bronchopulmonary segments supplied by native pulmonary arteri es, and initial placement of a systemic-pulmonary artery shunt. Competing risks analysis for initially palliated patients predicted that after 10 years, 68%ac hieved complete repair(with associated factors including later birth cohort and more bronchopulmonary segments supplied by native pulmonary arteries), 22%died without repair, and 10%remained alive without repair. Reoperations after comple te repair occurred in 38 children(27%), with risk factors including older age a t palliation, MAPCAs, and more segments supplied by collaterals. CONCLUSIONS: Ou tcomes in children with PAVSD have improved over time, and are better in complet ely repaired cases. Bronchopulmonary arterial supply is an important determinant of mortality, achievement of definitive repair, and post-repair reoperation. | Amark K.M. Karamlou T. O'Carroll A. B.W.McCrindle 田志 | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，2，9： | 4 |
| 2 | Dentin dysplasia: review of the literature and a proposed subclassification based on radiographic findings显示文摘 | O Carroll MK Duncan WK Perkins TM | 1991 | Oral Surg Oral Med Oral Pathol1991，72，1： | 1 |
| 3 | The liability of newhess: age dependence in organizationol death rates 显示文摘 | Freeman J Carroll O R Hannen M T | 1983 | American Sociological Review1983，48，5： | 1 |
| 4 | Blimpl is a critical determinant of the germ cell lineage in mice 显示文摘 | Ohinata Y Payer B O'Carroll D | 2005 | Nature2005，436，： | 1 |
| 5 | Maternal microRNAs are essential for mouse zygotic development 显示文摘 | TANG F KANEDA M O' CARROLL D | 2007 | Genes & development2007，21，6： | 1 |
| 6 | Cerebellar neurodegeneration in the absence of microRNAs显示文摘 | Schaefer A O\'Carroll DON Tan CL | 2007 | Journal of Experimental Medicine2007，204，7： | 1 |
| 7 | A model for co-expression pattern analysis of genes implicated in angiogenesis and tumour cell invasion in cervical cancer显示文摘 | Van-Trappen P O Ryan A Carroll M | 2002 | Br J Cancer2002，87，5： | 1 |
| 8 | Distribution of mRNA encoding B78/apj, the rat homologue of the human APJ receptor, and its endogenous ligand apelin in brain and peripheral tissues显示文摘 | O'Carroll AM Selby TL Palkovits M | 2000 | Biochim Biophys Acta2000，1492，1： | 1 |
| 9 | MicroRNAs are tightly as-sociated with RNA-induced gene silencing complexes in vivo显示文摘 | Tang F Hajkova P O'Carroll D | 2008 | Biochem Biophys Res Commun2008，372，1： | 1 |
| 10 | Mater-nal microRNAs are essential for mouse zygotic development显示文摘 | Tang F Kaneda M O'Carroll D | 2007 | Genes Dev2007，21，6： | 1 |
| 11 | Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs显示文摘 | Yi R O'Carroll D Pasolli HA | 2006 | Nature Genet2006，38，3： | 1 |
| 12 | Nanoscale zero valent iron and bimetallic particles for contaminated site remediation显示文摘 | O'Carroll D Sleep B Krol M | 2013 | Advances in Water Resources2013，51，1： | 1 |
| 13 | A 7-deaza-adenosine analog is a potent and selective inhibitor of hepatitis C virus replication with excellent pharmacokinetic properties显示文摘 | Olsen D B Eldrup AB Bartholomew L Bhat B Bosserman M R Ceccacci A Colwell L F Fay J F Flores O A Getty K L Grobler J A LaFemina R L Markel E J Migliaccio G Prhavc M Stahlhut M W Tomassini J E MacCoss M Hazuda D J Carroll S S | | 0，，10： | 1 |
| 14 | Blimpl and the emergence of the germ line during development in the mouse 显示文摘 | Saitou M Payer B O'Carroll D | 2005 | Cell Cycle2005，4，： | 1 |
| 15 | Information needs in public health and health policy:results of recent studies显示文摘 | O'Carroll PW | 1998 | J Urban Health1998，75，4： | 1 |
| 16 | Independent factors associated with mortality,reintervention,and achievement of complete repair in children with pulmonary atresia with ventricular septal defect显示文摘 | Amark KM Karamlou T O Carroll A | 2006 | J Am Coll Cardiol2006，47，7： | 1 |
| 17 | Rapid genotyping of Pseudomonas aeruginosa isolates harboured by adult and paediatric patients with cystic fibrosis using repetitive-element-based PCR assays 显示文摘 | Syrmis MW O' Carroll MR Sloots TP | 2004 | J Med Microbiol2004，53，1： | 1 |
| 18 | Independent factors associated with mortality reintervention,and achievement of complete repair in children with pulmonary atresia with ventricular septaldefect显示文摘 | Amark KM Karamlou T O'Carroll A | | 0，，07： | 1 |
| 19 | Blimp1 defines a progenitor population that governs cellular input to the scbaceous gland显示文摘 | Horsley V O'Carroll D Tooze R | 2006 | Cell2006，126，3： | 1 |
| 20 | Endophytic fungi in ev- ergreen shrubs in western Oregon: a preliminary study 显示文摘 | Petrini O Stone J Carroll FE | 1982 | Can J Bot1982，60，6： | 1 |
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