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| 1 | Cervical cancer screening in developing countries at a crossroad:Emerging technologies and policy choices显示文摘Cervical cancer(CC) represents the fourth most common malignancy affecting women all over the world and is the second most common in developing areas. In these areas,the burden from disease remains important because of the difficulty in implementing cytology-based screening programmes. The main obstacles inherent to these countries are poverty and a lack of healthcare infrastructures and trained practitioners. With the availability of new technologies,researchers have attempted to find new strategies that are adapted to low- and middle-income countries(LMIC) to promote early diagnosis of cervical pathology. Current evidence suggests that human papillomavirus(HPV) testing is more effective than cytology for CC screening. Therefore,highly sensitive tests have now been developed for primary screening. Rapid molecular methods for detecting HPV DNA have only recently been commercially available. This constitutes a milestone in CC screening in low-resource settings because it may help overcome the great majority of obstacles inherent to previous screening programmes. Despite several advantages,HPV-based screening has a low positive predictive value for CC,so that HPVpositive women need to be triaged with further testing to determine optimal management. Visual inspection tests,cytology and novel biomarkers are some options. In this review,we provide an overview of current and emerging screening approaches for CC. In particular,we discuss the challenge of implementing an efficient cervical screening adapted to LMIC and the opportunity to introduce primary HPV-based screening with the availability of point-of-care(POC) HPV testing. The most adapted screening strategy to LMIC is still a work in progress,but we have reasons to believe that POC HPV testing makes part of the future strategies in association with a triage test that still needs to be defined. | Rosa Catarino Patrick Petignat Gabriel Dongui Pierre Vassilakos | 2015 | World Journal of Clinical Oncology2015，6，6： | 16 |
| 2 | A Transcriptome Atlas of Physcomitrella patens Provides Insights into the Evolution and Development of Land Plants显示文摘 | Carlos Ortiz-Ramirez Marcela Hernandez-Coronado Anna Thamm Bruno Catarino Mingyi Wang Liam Dolan Jose A.Feijo Jorg D. Becker | 2016 | Molecular Plant2016，9，2： | 2 |
| 3 | 循环DNA与非小细胞肺癌:过往发现与新视角显示文摘肺癌是一个全球性问题。50%的患者被确诊时已经进展为无法治愈的晚期疾病,尽管临床医生不断努力,但各种化学治疗(化疗)方案获得的疗效均很有限。 | Raquel Catarino Ana Coelho Rui Medeiros 刘伟 吴绮楠 | 2013 | 国际病理科学与临床杂志2013，33，6： | 2 |
| 4 | Oncogenic virus-associated neoplasia: a role for cyclin D1 genotypes influencing the age of onset of disease? 显示文摘 | Catarino R Pereira D Breda E | 2008 | Biochem Biophys Res Commun2008，370，1： | 1 |
| 5 | Fetal lipoprotein changes in pre-eclampsia 显示文摘 | Catarino C Rebelo I Belo L | 2008 | Acta Obstetricia Gynecologiea2008，87，6： | 1 |
| 6 | Neon gas-gap heat switch显示文摘 | CATARINO I BONFAIT G DUBAND L | 2008 | Cryogenics2008，48，： | 1 |
| 7 | Influence of DNA repair RAD51 gene variants in overall survival of non-small cell lung cancer patients treated with first line chemotherapy显示文摘 | Nogueira A Catarino R Coelho A | 2010 | Cancer Chemother Pharmacol2010，66，3： | 1 |
| 8 | Oncogenic virus-associated neoplasia: a role for cyclin D1 genotypes influencing the age of onset of disease显示文摘 | CATARINO R PEREIRA D BREDA E | 2008 | Biochemical and Biophysical Research Communications2008，370，1： | 1 |
| 9 | Cervical cancer and CYP2E1 polymorphisms:implications for molecular epidemiolo- gy显示文摘 | Ferreira PM Catarino R Pereira D | 2006 | Eur J Clin Pharmacol2006，62，1： | 1 |
| 10 | Inflammatory Disturb- ances in Preeclampsia: Relationship between Maternal and Um- bilical Cord Blood 显示文摘 | Catarino C Santos-Silva A Belo L | 2012 | Journal of Pregnancy2012，，68： | 1 |
| 11 | Progressive subcutaneous em- physema and respiratory arrest 显示文摘 | Abu-Omar Y Catarino PA | 2002 | J R Soc Med2002，95，2： | 1 |
| 12 | The monoid of orientation-preserving mappings on a chain显示文摘 | CATARINO P M HIGGINS P M | 1999 | Semigroup Forum1999，58，2： | 1 |
| 13 | Effects of sea water a- cidification on early development of the intertidal sea urchin Para- centrotus lividus( Lamarck 1816)显示文摘 | Moulin L Catarino A I Claessens T | 2011 | Marine Pollution Bulletin2011，62，： | 1 |
| 14 | Efficacy and tolerability of airway stents 显示文摘 | Valente C Catarino A Jorge Ferreira A | 2010 | Rev Port Pneumol2010，16，3： | 1 |
| 15 | The cellular location of Cu in lichens and its effects on membrane integrity and chlorophyll fluorescence显示文摘 | Branquinho C Brown D H Catarino F | 1997 | Environ Exp Bot1997，38，： | 1 |
| 16 | Accumulation of Zn, Pb, Cu, Cr and Ni in sediments between roots of the Tagus estuary salts marshes, Portugal 显示文摘 | Carador I Vale C Catarino F | 1996 | Estums i Coast and Shelf Sci1996，42，4： | 1 |
| 17 | Estrogen and progesterone receptors in gastric and colorectal eancer显示文摘 | Oshima CT Wonraht DR Catarino RiM | 1999 | Hepatogastro-enterology1999，46，30： | 1 |
| 18 | Non-alcoholic beer-A new industrial process显示文摘 | MARGARIDA CATARINO | 2011 | Separation and Purification Technology2011，79，3： | 1 |
| 19 | The CYP3A4*1B polymorphism and prostate cancer susceptibility in a Portuguese population显示文摘 | Ana Nogal Ana Coelho Raquel Catarino | 2007 | Cancer Genet Cytogenet2007，177，2： | 1 |
| 20 | The Monoid of Orientation Preserving Mappings on a Chain 显示文摘 | CATARINO P M HIGGINS P M | 1999 | Semigroup Forum1999，58，2： | 1 |
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