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| 1 | 为期四年的临床试验对噻托溴铵在慢性阻塞性肺疾病中的疗程评价显示文摘背景和目的:进一步观察噻托溴铵治疗COPD的长期效果。方法:通过随机、双盲试验,比较为期4年的噻托溴铵治疗COPD患者的疗效,4年期间允许患者使用除吸入抗胆碱能药物以外的任何呼吸科常用药物。要求患者年龄在40岁以上,使用支气管舒张剂后FEV1占预计值%≤70%,且FEV,/FVC占预计值%70%。主要终点是从第30天开始使用支气管舒张剂前后FEV1平均下降率。次要终点包括FVC测量值、圣乔治呼吸问卷(SGRQ)结果的变化、COPD急性加重以及病死率。结果:共入组5993例, | Tashkin DP Celli B Senn S 金建敏 孙永昌 | 2009 | 中华结核和呼吸杂志2009，32，3： | 2 |
| 2 | A 4-year trial of tiotropium in chronic obstructive pulmonary disease显示文摘 | Tashkin DP Celli B Senn S | 2008 | N Engl J Med2008，359，15： | 1 |
| 3 | Tiotropium HandiHal- er in the treatment of COPD : a safety review 显示文摘 | Kesten S Celli B Deeramer M | 2009 | Int J Chron Obstruct Pulmon Dis2009，4，： | 1 |
| 4 | A 4-year trial oftiotropium in chronic obstructive pulmonary disease 显示文摘 | Tashkin DP Celli B Senn S | 2008 | NEngl J Med2008，359，15： | 1 |
| 5 | Population impact of different definitions of airway obstruction 显示文摘 | Celli BR Halbert R J Isonaka S | 2003 | Eur Respir J2003，22，2： | 1 |
| 6 | A 4-year trial of tiotropium in chronic obstructive pulmonary disease显示文摘 | Tashkin DP Celli B Senn S | 2008 | N Engl J Med2008，359，15： | 1 |
| 7 | Effect of tiotropium on outcomes in patients with moderate chronic obstructive pulmonary disease (UPLIFT): a prespecified subgroup analysis of a randomised controlled trial 显示文摘 | Decramer M Celli B Kesten S | 2009 | Lancet2009，374，9696： | 1 |
| 8 | A multiobjective algorim for出e sizing and siting of distributed generation 显示文摘 | CELLI G GHIANI E MOCCr S | 2005 | IEEE Transactions on Power Systems2005，20，5： | 1 |
| 9 | Improvement in resting inspiratory capacity and hyperinflation with tiotropium in COPD patients with increased static lung volumes 显示文摘 | Celli B Zuwallack R Wang S | 2003 | Chest2003，124，5： | 1 |
| 10 | A 4-year trial of tiotropium in chronic obstructive pulmonary disease 显示文摘 | Tashkin DP Celli B Senn S | 2008 | N Engl J Med2008，359，15： | 1 |
| 11 | Improvement in resting inspiratory capacity and hyperinflation with tiotropium in COPD patients with increased static lung volumes显示文摘 | Celli B ZuWallack R Wang S | 2003 | Chest2003，124，5： | 1 |
| 12 | A controlled trial of intermittent positive pressure breathing, incentive spirometry, and deep breathing exercises in preventing pulmonary complications after abdominal surgery显示文摘 | Celli B R Rodriguez K S Snider G L | 1984 | Am Rev Respir Dis1984，130，1： | 1 |
| 13 | A 4-year trial of tiotropium in chronic obstructive pulmonary disease显示文摘 | Tashkin D P Celli B Senn S | 2008 | N Engl J Med2008，359，15： | 1 |
| 14 | Usefulness of contrast-enhanced perfusional sonography in the assessment of hepatocellular carcinoma hypervascular at spiral computed tomography显示文摘 | Gaiani S Celli N Piscaglia F | 2004 | J Hepatol2004，41，3： | 1 |
| 15 | A novel, orally active CXCR1/2 receptor antagonist, Sch527123, inhibits neutrophil recruitment, mucus production,and goblet cell hyperplasia in animal models of pulmonary inflammation 显示文摘 | CHAPMAN R W MINNICOZZI M CELLY C S | 2007 | J Pharmaeol Exp Ther2007，322，2： | 1 |
| 16 | Cell-penetrating anti-GFAP VHH and corresponding fluorescent fusion protein VHH-GFPspontaneously cross the blood-brain barrier and specifically recognize astrocytes:application to brain imaging显示文摘 | Li T Bourgeois JP Celli S | | 0，，： | 1 |
| 17 | Characterization of liver lesions by real-time contrast-enhanced ultrasonography显示文摘 | Celli N Gaiani S Piscaglia F | 2007 | Eur J Gastroenterol Hepatol2007，19，1： | 1 |
| 18 | A 4-year trial of tiotropium in chronic obstructive pulmonary disease显示文摘 | Tashkin DP Celli B Senn S | 2008 | N Eng!J Med2008，359，15： | 1 |
| 19 | A multi-objective evolutionary algorithm for the sizing and siting of distributed Generation显示文摘 | Celli G Ghiani E Mocci S | 2005 | IEEE Trans on Power Systems2005，20，2： | 1 |
| 20 | A 4-year trial of tiotropium in chronic obstructive pulmonary disease显示文摘 | Tashkin DP Celli B Senn S | 2008 | N Engl J Med2008，359，15： | 1 |
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