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| 1 | IL-23 signaling enhances Th2 polarization and regulates allergic airway inflammation显示文摘 | Juan Peng Xuexian O Yang Seon Hee Chang Jiong Yang Chen Dong | 2010 | Cell Research2010，20，1： | 31 |
| 2 | Grain refining of magnesium alloy AZ31 by rolling显示文摘 | Tien-Chan Chang Jian-Yi Wang Chia-Ming O Shyong Lee | 2003 | Journal of Materials Processing Tech2003，，： | 2 |
| 3 | Drained,undrained,consolidating and dynamic behaviour assumptions in solis; Limits of validity 显示文摘 | Zienkiewicz O C Chang C T Bettess P | 1980 | Geotechnique1980，30，： | 2 |
| 4 | Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model显示文摘 | Janaiah Kota Raghu R. Chivukula Kathryn A. O’Donnell Erik A. Wentzel Chrystal L. Montgomery Hun-Way Hwang Tsung-Cheng Chang Perumal Vivekanandan Michael Torbenson K. Reed Clark Jerry R. Mendell Joshua T. Mendell | 2009 | Cell2009，，6： | 2 |
| 5 | ^(99m)TC-Methylene diphosphonate uptake at injury site correlates with osteoblast differentiation and mineralization during bone healing in mice显示文摘99m Tc-Methylene diphosphonate(99m Tc-MDP) is widely used in clinical settings to detect bone abnormalities.However, the mechanism of99 m Tc-MDP uptake in bone is not well elucidated. In this study, we utilized a mouse tibia injury model, single-photon emission computed tomography(gamma scintigraphy or SPECT),ex vivo micro-computed tomography, and histology to monitor99 m Tc-MDP uptake in injury sites during skeletal healing. In an ex vivo culture system, calvarial cells were differentiated into osteoblasts with osteogenic medium, pulsed with99 m Tc-MDP at different time points, and quantitated for99 m Tc-MDP uptake with a gamma counter. We demonstrated that99 m Tc-MDP uptake in the injury sites corresponded to osteoblast generation in those sites throughout the healing process. The99 m Tc-MDP uptake within the injury sites peaked on day 7 post-injury, while the injury sites were occupied by mature osteoblasts also starting from day 7.99 m Tc-MDP uptake started to decrease 14 days post-surgery, when we observed the highest level of bony tissue in the injury sites. We also found that99 m Tc-MDP uptake was associated with osteoblast maturation and mineralization in vitro. This study provides direct and biological evidence for99 m Tc-MDP uptake in osteoblasts during bone healing in vivo and in vitro. | Zhendong A Zhong Anderson Peck Shihong Li Jeff Van Oss John Snider Casey J Droscha Tingtung A Chang Bart O Williams | 2015 | Bone Research2015，3，2： | 2 |
| 6 | Personalising pancreas cancer treatment:When tissue is the issue显示文摘The treatment of advanced pancreatic cancer has not moved much beyond single agent gemcitabine until recently when protocols such as FOLFIRINOX(fluorouracil,leucovorin,irinotecan and oxaliplatin)and nab-paclitaxelgemcitabine have demonstrated some improved outcomes.Advances in technology especially in massively parallel genome sequencing has progressed our understanding of the biology of pancreatic cancer especially the candidate signalling pathways that are involved in tumourogenesis and disease course.This has allowed identification of potentially actionable mutations that may be targeted by new biological agents.The heterogeneity of pancreatic cancer makes tumour tissue collection important with the aim of being able to personalise therapies for the individual as opposed to a one size fits all approach to treatment of the condition.This paper reviews the developments in this area of translational research and the ongoing clinical studies that will attempt to move this into the everyday oncology practice. | Katrin M Sjoquist Venessa T Chin Lorraine A Chantrill Chelsie O'Connor Chris Hemmings David K Chang Angela Chou Marina Pajic Amber L Johns Adnan M Nagrial Andrew V Biankin Desmond Yip | 2014 | World Journal of Gastroenterology2014，20，24： | 2 |
| 7 | Phenolic compounds and their changes in apples during maturation and cold storage 显示文摘 | Stanislaw B Wieslaw O Chang Y L | 1990 | J Agric Food Chem1990，38，4： | 1 |
| 8 | Validation of a FEA tire model for vehicle dynamic analysis and full vehicle real time proving ground simulations显示文摘 | Jeong W K John O H | | SAE Paper0，18，： | 1 |
| 9 | Effects of membrane foul- ing on solute rejection during membrane filtration of acti- vated sludge 显示文摘 | Chang I S Bag S O Lee C H | 2001 | Process Biochem2001，36，89： | 1 |
| 10 | Fuzzy Regression Methods-a Comptive Assessment显示文摘 | Chang Y H O Ayyub B M | 2001 | Fuzzy Sets and Systems2001，119，： | 1 |
| 11 | Hemoglobin Concentrations Influence Birth Outcomes in Pregnant Afican- American Adolesents显示文摘 | Chang S C O'Brian K O Nathanson M S | | 0，，07： | 1 |
| 12 | Development of a reverse transcription nested polymerase chain reaction assay for differential diagnosis of transmissible gastroenteritis virus and porcine respiratory coronavirus from feces and nasal swabs of infected pigs显示文摘 | Chang K O Sestak K | 2000 | J Vet Diagn Invest2000，12，4： | 1 |
| 13 | Simultaneous presentation of Kimura disease and angiolymphoid hyperplasia With eosinophil- ia显示文摘 | Esmaili D Chang E O'Hearn T | 2008 | Ophthal Plast Reconstr Surg2008，24，4： | 1 |
| 14 | Group contribution analysis of the damping behavior of homopolymers,statistical copolymers and interpenetrating polymer networks based on acrylic,vinyl and styrenicmers显示文摘 | CHANG M C O THOMAS D PERLING L H | | 0，，： | 1 |
| 15 | Stable expression of a Norwalk virus RNA replicon in a human hepatoma cell line显示文摘 | Chang K O Sosnovtsev S V Belliot G | 2006 | Virology2006，353，2： | 1 |
| 16 | The impact of substance abuse on mortality in patients with severe traumatic brain injury显示文摘 | O'Phelan K McArthur DL Chang CW | 2008 | J Trauma2008，65，3： | 1 |
| 17 | The use of gas bubbling to enhance membrane processes 显示文摘 | Cui Z F Chang S Fane A O | 2003 | J Membr Sci2003，221，： | 1 |
| 18 | Inhibition of histone demethylases by 4-carboxy-2, 2 ' -bipyridyl compounds显示文摘 | Chang K H King O N F Tumber A | 2011 | ChenledChem2011，6，5： | 1 |
| 19 | Diffusion-weighted MR imaging of metastastic disease of the spine: assessment of response to therapy显示文摘 | Byun W M Shin S O Chang Y | 2002 | AJNR2002，23，6： | 1 |
| 20 | Effects of membrane fouling on solute rejection during membrane filtration of activated sludge 显示文摘 | Chang I S Bag S O Lee C H | 2001 | Process Biochemistry2001，36，89： | 1 |
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