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| 1 | Nociception at the diabetic foot,an uncharted territory显示文摘The diabetic foot is characterised by painless foot ulceration and/or arthropathy;it is a typical complication of painless diabetic neuropathy.Neuropathy depletes the foot skin of intraepidermal nerve fibre endings of the afferent A-delta and C-fibres,which are mostly nociceptors and excitable by noxious stimuli only.However,some of them are cold or warm receptors whose functions in diabetic neuropathy have frequently been reported.Hence,it is well established by quantitative sensory testing that thermal detection thresholds at the foot skin increase during the course of painless diabetic neuropathy.Pain perception(nociception),by contrast,has rarely been studied.Recent pilot studies of pinprick pain at plantar digital skinfolds showed that the perception threshold was always above the upper limit of measurement of 512 m N(equivalent to 51.2 g) at the diabetic foot.However,deep pressure pain perception threshold at musculus abductor hallucis was beyond 1400 k Pa(equivalent to 14 kg;limit of measurement) only in every fifth case.These discrepancies of pain perception between forefoot and hindfoot,and between skin and muscle,demand further study.Measuring nociception at the feet in diabetes opens promising clinical perspectives.A critical nociception threshold may be quantified(probably corresponding to a critical number of intraepidermal nerve fibre endings),beyond which the individual risk of a diabetic foot rises appreciably.Staging of diabetic neuropathy according to nociception thresholds at the feet is highly desirable as guidance to an individualised injury prevention strategy. | Ernst A Chantelau | 2015 | World Journal of Diabetes2015,6,3: | 7 |
| 2 | Progression of diabetic retinopathy during improved metabolic control may be treated with reduced insulin dosage and/or somatostatin analogue administration-a case report显示文摘 | Chantelau E Frystyk J | 2005 | Growth Hormone & IGF Research2005,15,2: | 1 |
| 3 | Antibiotic treatment for uncomplicated neuropathic forefoot ulcers in diabetes: a controlled trial显示文摘 | Chantelau E Tanudjaja T Ahenhofer F | 1996 | Diabet Med1996,13,2: | 1 |
| 4 | Effect of pa- tient-selected intensive insulin therapy on quality of life显示文摘 | Chantelau E Schiffers T Schutze J Hansen B | 1997 | Pa- tient Educ Couns1997,30,2: | 1 |
| 5 | Insulin, insu- lin analogues and diabetic retinopathy 显示文摘 | Chantelau E Kimmerle R Meyer2Schwickerath R | 2008 | Arch Physiol Bio chem2008,114,10: | 1 |
| 6 | Effect of patient - selected intensive insulin therapy on quality of life显示文摘 | Chantelau E Schiffers T Schutze J | 1997 | Patient Educ Couns1997,30,2: | 1 |
| 7 | Pressure pain thresholds at the diabetic Charcot foot: An exploratory study显示文摘 | Chantelau E Wienemann T Richter A | 2012 | J Museuloskelet Neuronal Interact2012,12,2: | 1 |
| 8 | Reversion of 'early worsening' of diabetic retinopathy by deliberate restoration of poor metabolic control显示文摘 | Chantelau E Meyer-Schwickerath R | 2003 | Ophthalmologica2003,217,5: | 1 |
| 9 | Evaluation of the diabetic Charcot foot by MR imag- ing or plain radiography-an observational study显示文摘 | Chantelau E Poll LW | 2006 | ExpClin Endocrinol Diabet2006,114,: | 1 |
| 10 | Effect of patient-selected intensive insulin therapy on quality of life 显示文摘 | Chantelau E Schiffers T Schutze J | 1997 | Patient Edu Couns1997,30,: | 1 |
| 11 | Progression of diabetic retinopathy during improved metabolic control may be treated with reduced insulin dosage and/or somatostatin analogue administration-a case report显示文摘 | Chantelau E Frystyk J | 2005 | Growth Hormone & IGF Research2005,15,2: | 1 |
| 12 | Effect of patient selected intensive insulin therapy on quality of life 显示文摘 | CHANTELAU E SCHIFFERS T SCHUTZE J | 1997 | Patient Edu Couns1997,30,2: | 1 |
| 13 | Treatment with insulin glargine(Lantus)increases the proliferative potency of the serum of patients with type-2 diabetes:apilot studyon MCF-7 breast cancer cells显示文摘 | Mayer D Chantelau E | 2010 | Arch Physiol Biochem2010,116,2: | 1 |
| 14 | Insulin,insulin analogues and diabetic retinopathy显示文摘 | Chantelau E Kimmerle R Meyer -Schwickerath R | 2008 | Arch Physiol Biochem2008,114,1: | 1 |
| 15 | Reversion of 'early worsening' of diabetic retinopathy by deliberate restoration of poor metaboliccontrol显示文摘 | Chantelau E Meyer-Schwickerath R | 2003 | Ophthalmologica2003,217,5: | 1 |
| 16 | Association of below-knee arterosclerosis to medial arterial calcification in diabetes mellitus显示文摘 | Chantelau E Lee KM Jungblut R | 1995 | Diab Res Clin Prac1995,29,: | 1 |
| 17 | Evaluation of the diabetic Charcot foot by MR imaging or plain radiography-an observational study显示文摘 | Chantelau E Poll LW | 2006 | Exp Clin Endocrinol Diabet2006,114,: | 1 |
| 18 | Effect of patient selected intensive insulin therapy on quality of life显示文摘 | Chantelau E Schiffers T Schutze J | 1997 | Patient Edu Couns1997,30,: | 1 |
| 19 | Severe lipoatrophy with human insulin:successfully treated by CSII显示文摘 | Chantelau E Reuter M Schotes S | 1993 | Diabet Med1993,10,: | 1 |
| 20 | Effect of patient-selected intensive insulin therapy on quality of life显示文摘 | Chantelau E Schiffers T Schütze J | 1997 | Patient Educ Couns1997,30,2: | 1 |