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95篇 您的检索式:作者名="les Morgan"
    题名 作者 年代 出处 被引量
1Small ubiquitin-related modifier paralogs are indispensable but functionally redundant during early development of zebrafish显示文摘到许多蛋白质的小 ubiquitin 相关的修饰词(相扑) 变化形式调整多样的细胞的过程,包括抄写,房间周期规定和染色体正直的维护。在 vivo 调查相扑 paralogs 的生物功能,我们在 zebrafish 的早开发使他们失去活性。当作为 Ubc9 缺乏的,为所有三相扑 paralogs 缺乏的 zebrafish 胚胎显示了严重缺点时,单个相扑 paralog 的损失与正常开发兼容。相扑缺乏的胚胎能被一个单个人或 zebrafish 相扑救。当关键时结构的基本离氨酸残余和 N 终端相扑的未组织的段是批评的为在 vivo 营救, SUMO2 的一致 K11 sumoylation 地点是非必需的,在这个潜在的地点上暗示那链形成为正常开发是非本质的。所有三相扑的 Inactivation 触发了 p53 依赖的 apoptosis, p53 的进一步的 inactivation 恢复了正常 zebrafish 开发。有趣地,我们也证明 p53 的主导的否定截断的形式,螖 1 13p53,显著地弄钝相扑在 vivo 的导致弄空的 p53 活动。一起拿,我们的结果建议相扑 paralogs 不可缺少,却冗余,在 zebrafish 的早发展。Hao Yuan Jun Zhou Min Deng Xi Liu Morgane Le Bras Hugues de The Sai Juan Chen Zhu Chen Ting Xi Liu Jun Zhu 2010Cell Research2010,20,2:4
2Biological consequences and health risks of low - level exposure to ioni- zing radiation: commentary on the workshop 显示文摘Feinendegen LE Brooks AL Morgan WF 2011Health Physics2011,100,3:1
3Surgical anatomy of the analcanal and theoperative treatment of hemorrhoids显示文摘Milligan ETC Morgan CN Nanton LE 1937Lancet1937,2,1:1
4The spectrum of metabolic bone disease in lymphoblastic leukemia 显示文摘Cohn SL Morgan ER Mallette LE 1987Cancer1987,59,2:1
5Factors affecting oral feeding with severe traumatic brain injury 显示文摘Mackay LE Morgan AS Bernstein BA 1999J Head Trauma Rehabil1999,14,5:1
6Surgical anatomy of the anal canal and the operative treatment of hemorrhoids 显示文摘Milligan ETC Morgan CN Nanton LE 1937Lancet1937,2,:1
7Surgical anat only of the anal canal and the operative treatment of hemorrhoids显示文摘 Morgan CN Nanton LE 1937Lancet1937,2,8:1
8Salvage of tibial pilon frac-tures using fusing of the ankle with a 90 degrees cannulated blade-plate:a preliminary report显示文摘Morgan SJ Thordarson DB Shepherd LE 1999Foot Ankle Int1999,6,:1
9Serial echocardiographic assessment of left ventricular geometry and function after large myocardial infarction in the rats显示文摘 Katz LE Morgan JP 1994Circulation1994,89,:1
10Surgical anatomy of the anal canal and the operative treatment of hemorrhoids显示文摘Miligan ETC Morgan CN Nanton LE 1937Lancet1937,2,:1
11Salvage of tibial pilon fractures using fusion of the ankle with a 90 degrees cantmlated bladeplate : apreliminary report显示文摘Morgan SJ Thordarson DB Shepherd LE 1999Foot Anbte Int1999,20,:1
12Surgical anatomy of the analcanal and the operative treatment of hemorrhoids显示文摘Milligan ET Morgan CN Nanton LE 0,,01:1
13Inflammation and dephosphorylation of the tight junction protein occludin in an experimental model of multiple scle- rosis显示文摘Morgan L Shah B Rivers LE 2007Neuroseience2007,147,3:1
14Surgical anatomy of the anal canal, and the operative treatment of haemorrhoids显示文摘Milligan ETC Morgan CN Jones LE 1937Lancet1937,230,5959:1
15Swallowing disor- ders in severe brain injury:risk factors affecting htum to oral intake 显示文摘Mackay LE Morgan AS Bemstein BA 1999Arch Phys Med Rehabil1999,,80:1
16Surgical anato- my of the anal canal and the operative treatment of hemor- rhoids显示文摘Milligan ETC Morgan CN Nanton LE et a/ 1937Lancet1937,230,5959:1
17Salvage of tibial Pilon fractures using fusion of the ankle with a 90 degrees eannulated blade-plate: a preliminary report显示文摘Morgan SJ Thordarson DB Shepherd LE 1999Foot Ankle Int1999,20,:1
18Surgical anatomy of the anal canal and the operative treatment of hemorrhoids显示文摘 Morgan CN Naaton LE 1937Lancet1937,2,:1
19Post-fire burn severity and vegetation response following eight large wildfires across the western United States 显示文摘LENT MORGAN P HUDAK A T 2007Fire Ecology2007,3,1:1
20Surgical anatomy of the anal canal and the operative treatment of hemorrhoids显示文摘Miligan ETC Morgan CN Nanton LE 1937Lancet1937,2,:1
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