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| 1 | 螺内酯与可乐定作为难治性高血压第4种治疗药物的比较:难治性高血压的最佳治疗随机研究显示文摘该研究旨在通过一个多中心随机试验对作为难治性高血压患者的第4种治疗药物的螺内酯与可乐定进行比较。采用药丸计数评估药物治疗依从性。难治性高血压患者(定义为包括1种利尿剂在内的3种药物治疗12周,诊室及动态血压监测血压仍未控制)随机给予螺内酯(12.5~50 mg/d)或可乐定(0.1~0.3mg,2次/d)继续治疗12周。 | Krieger EM Drager LF Giorgi DMA Pereira AC Barreto-Filho JAS Nogueira AR Mill JG Lotufo PA Amodeo C Batista MC Bodanese LC Carvalho ACC Castro I Chaves H Costa EAS Feitosa GS Franco RJS Fuchs FD Guimarāes AC Jardim PC Machado CA Magalhāes ME Mion D Jr Nascimento RM Nobre F Nóbrega AC Ribeiro ALP Rodrigues-Sobrinho CR Sanjuliani AF Teixeira MDCB Krieger JE ReHOT Investigators 赵狄 练桂丽 | 2018 | 中华高血压杂志2018，26，3： | 7 |
| 2 | Assessing the relationship between the rumen microbiota and feed efficiency in Nellore steers显示文摘Background:Ruminants rely upon a complex community of microbes in their rumen to convert host-indigestible feed into nutrients.However,little is known about the association between the rumen microbiota and feed efficiency traits in Nellore(Bos indicus)cattle,a breed of major economic importance to the global beef market.Here,we compare the composition of the bacterial,archaeal and fungal communities in the rumen of Nellore steers with high and low feed efficiency(FE)phenotypes,as measured by residual feed intake(RFI).Results:The Firmicutes to Bacteroidetes ratio was significantly higher(P<0.05)in positive-RFI steers(p-RFI,low feed efficiency)than in negative-RFI(n-RFI,high feed efficiency)steers.The differences in bacterial composition from steers with high and low FE were mainly associated with members of the families Lachnospiraceae,Ruminococcaceae and Christensenellaceae,as well as the genus Prevotella.Archaeal community richness was lower(P<0.05)in p-RFI than in n-RFI steers and the genus Methanobrevibacter was either increased or exclusive of p-RFI steers.The fungal genus Buwchfawromyces was more abundant in the rumen solid fraction of n-RFI steers(P<0.05)and a highly abundant OTU belonging to the genus Piromyces was also increased in the rumen microbiota of highefficiency steers.However,analysis of rumen fermentation variables and functional predictions indicated similar metabolic outputs for the microbiota of distinct FE groups.Conclusions:Our results demonstrate that differences in the ruminal microbiota of high and low FE Nellore steers comprise specific taxa from the bacterial,archaeal and fungal communities.Biomarker OTUs belonging to the genus Piromyces were identified in animals showing high feed efficiency,whereas among archaea,Methanobrevibacter was associated with steers classified as p-RFI.The identification of specific RFI-associated microorganisms in Nellore steers could guide further studies targeting the isolation and functional characterization of rumen microbes potentially important for the energy-harvesting efficiency of ruminants. | Déborah Romaskevis Gomes Lopes Márcio de Souza Duarte Alex J.La Reau Ibrahim Zuniga Chaves Tiago Antônio de Oliveira Mendes Edenio Detmann Cláudia Braga Pereira Bento Maria Eugênia Zerlotti Mercadante Sarah Figueiredo Martins Bonilha Garret Suen Hilário Cuquetto Mantovani | 2021 | Journal of Animal Science and Biotechnology2021，12，4： | 3 |
| 3 | Mechanisms ofbioleaching of a refractory mineral of gold with Thiobacillus ferrooxidans 显示文摘 | Nestor D Valdivia U Chaves A P | 2001 | Int J Miner Process2001，62，： | 2 |
| 4 | Immunogenicity of hepatitis B vaccine among hemodialysis patients: Effect of revaccination of non-responders and duration of protection显示文摘 | Sandra S. Chaves Danni Daniels Brian W. Cooper Susan Malo-Schlegel Susan MacArthur Karen C. Robbins John F. Kobetitsch Aimee McDaniel John F. D’Avella Miriam J. Alter | 2011 | Vaccine2011，，52： | 2 |
| 5 | Tree allometry and improved estimation of carbon stocks and balance in tropical forests显示文摘 | Chave J Andalo C Brown S Cairns M A Chambers J Q Eamus D Folster H Fromard F Higuchi N Kira T Lescure J P Nelson B W Ogawa H Puig H Riera B Yamakura T | | 0，，： | 1 |
| 6 | On the robust estimation of power spectra, coherences, and transfer functions显示文摘 | Chave A D Thomson D J Ander M E | 1987 | Journal of Geophysical Research1987，92，1： | 1 |
| 7 | Brucella abortus uses a stealthy strategy to avoid activation of the innate immune system during the on set of infection 显示文摘 | Barquero C Chaves E Weiss D S | 2007 | PloS One2007，2，7： | 1 |
| 8 | Controlled electromagnetic sources for measuring electrical conductivity beneath the oceans, 1 : Forward problem and model study显示文摘 | Chave A D Cox C S | 1982 | Journal of Geophysical Research1982，87，7： | 1 |
| 9 | Analysis of chlorothaloniland degradation products in soil and water by GC/MS and LC/MS显示文摘 | CHAVES A SHEA D DANEHOWER D | 2008 | Chemosphere2008，71，4： | 1 |
| 10 | Some comments on rrmgnetotelluric response function estimation 显示文摘 | Chave A D Thomson D J | 1989 | Journal of Geophysical Research1989，94，14： | 1 |
| 11 | Controlled source electromagnetic sounding of the oceanic lithosphere显示文摘 | Cox C S Constable S Chave A D | 1986 | Nature1986，320，1： | 1 |
| 12 | Prevention of vaficella : recommendations of the Advisory Committee on Immunization Practices (ACIP)显示文摘 | Matin M Guris D Chaves SS etc | 2007 | MMWR Recomm Rep2007，56，4： | 1 |
| 13 | Electromagnetic Induction by a Finite Electric Dipole Source Over a 2-D Earth显示文摘 | Unsworth M J Travis B J Chave A D | 1993 | Geophysics1993，58，1： | 1 |
| 14 | On the theory of sea-floor conductivity mapping using transient EM systems显示文摘 | CheesmanS J Edwards R N Chave A D | 1987 | Geophysics1987，52，2： | 1 |
| 15 | A transient dipole-dipole method for mapping the conductivity of the seafloor 显示文摘 | Edwards R N Chave A D | 1986 | Geophysics1986，51，4： | 1 |
| 16 | Serum levels of S100B and NSE proteins in Alzheimer's disease patients显示文摘 | CHAVES M L CAMOZZATO A L FERREIRA E D | 2010 | J Neurointlammation2010，27，6： | 1 |
| 17 | Piperdardine, a piperidine alkaloid from Piper tuberculatum 显示文摘 | Araujo-Junior J X D V L Da-Cunha E O Chaves M C D | 1997 | Phytochemistry1997，44，3： | 1 |
| 18 | Northeastern Pacific mantle conductivity profile from long-period magnetotelluric sounding using Hawaii-to-California submarine cable data显示文摘 | LIZARRALDE D CHAVE A SCHULTZ A | 1995 | Journal of Geophysical Research1995，100，17： | 1 |
| 19 | Prevention of varicella: recommendations of the Advisory Committee on Immunization Practices (ACIP)显示文摘 | Marin M Gtlris D Chaves SS | 2007 | MMWR Recomm Rep2007，56，4： | 1 |
| 20 | Epoxy silanes in reactive polymer emulsions 显示文摘 | CHEN M J OSTERHOLTZ F D CHAVES A | 1997 | Journal of Coatings Technology1997，69，875： | 1 |
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