|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models显示文摘表示为基于 radiopharmaceutical 的成像为生物体之发光成像或 HSV1 thymidine kinase (HSV1-TK ) 编码任何一个萤火虫酶(fLuc ) 的记者 transgene 的 lentiviral 向量的二种新类型被构造监视人的胚胎的干细胞(hESC ) 在在移植以后的活老鼠的嫁接和增长。任何一个 transgene 的组成的表示没在文化改变 hESCs 的性质。我们下次在 SCID 鼠标监视了 teratomas 的形成到测试(1 ) 是否修改基因的 hESCs 维持他们的发展 pluripotency,并且(2 ) 是否支撑了记者基因表示,允许 noninvasive,在一个活鼠标模型的 hESC 衍生物的整个身体的成像。我们在接种以后从修改基因的房间以及野类型的 hESCs 2-4 月的两种类型观察了 teratoma 形成。用一个光成像系统,从 fLuc-transduced hESCs 的生物体之发光容易在在摸得出的肿瘤能被检测以前,长忍受 teratomas 的老鼠被检测。开发一个 noninvasive 成像方法对诊所更容易地可译,我们也利用了 HSV1-TK 和它的特定的底层, 1-(2 鈥 ? deoxy-2 鈥 ?fluoro- 尾 - D-arabinofuranosyl )-5-[125I]iodouracil ([125I ] FIAU ) ,记者 / 探查对。在全身的管理以后,[125I ] FIAU 是仅仅由编码 transgene 的 HSV1-TK 酶的 phosphorylated 并且在 transduced 以内保留(并且移植) 房间,由单个光子的排放允许敏感、量的成像计算了断层摄影术。象这些那样的 Noninvasive 成像方法可以使我们能在实时接受者以内重复地监视移植人的干细胞的存在和分发在上一通过记者基因的表达式长期。 | Martin G Pomper Holly Hammond Xiaobing Yu Zhaohui Ye Catherine A Foss Doris D Lin James J Fox Linzhao Cheng | 2009 | Cell Research2009，19，3： | 9 |
| 2 | Primer containing dimethylaminododecyl methacrylate kills bacteria impregnated in human dentin blocks显示文摘Antibacterial dimethylaminododecyl methacrylate(DMADDM) was recently synthesized. The objectives of this study were to:(1)investigate antibacterial activity of DMADDM-containing primer on Streptococcus mutans impregnated into dentin blocks for the first time, and(2) compare the antibacterial efficacy of DMADDM with a previous quaternary ammonium dimethacrylate(QADM).Scotchbond Multi-Purpose(SBMP) bonding agent was used. DMADDM and QADM were mixed into SBMP primer. Six primers were tested: SBMP control primer P, P+2.5% DMADDM, P+5% DMADDM, P+7.5% DMADDM, P+10% DMADDM, and P+10% QADM.S. mutans were impregnated into human dentin blocks, and each primer was applied to dentin to test its ability to kill bacteria in dentinal tubules. Bacteria in dentin were collected via a sonication method, and the colony-forming units(CFU) and inhibition zones were measured. The bacterial inhibition zone of P+10% DMADDM was 10 times that of control primer(Po0.05). CFU in dentin with P+10% DMADDM was reduced by three orders of magnitude, compared with control. DMADDM had a much stronger antibacterial effect than QADM, and antibacterial efficacy increased with increasing DMADDM concentration. Dentin shear bond strengths were similar among all groups(P40.1). In conclusion, antibacterial DMADDM-containing primer was validated to kill bacteria inside dentin blocks, possessing a much stronger antibacterial potency than the previous QADM. DMADDM-containing bonding agent was effective in eradicating bacteria in dentin, and its efficacy was directly proportional to DMADDM mass fraction. Therefore, DMADDM may be promising for use in bonding agents as well as in other restorative and preventive materials to inhibit bacteria. | Chen Chen Lei Cheng Michael D Weir Nancy J Lin Sheng Lin-Gibson Xue-Dong Zhou Hockin HK Xu | 2016 | International Journal of Oral Science2016，8，4： | 4 |
| 3 | Genetic transformation of wheat mediated by Agrobacterium tumefaciens显示文摘 | Cheng M Fry J E Pang S Zhou H Hironaka C M Duncan D R Conner T W Wan Y | 1997 | Plant Physiol1997，，： | 2 |
| 4 | Simultaneous detection of classical swine fever virus and North American genotype Porcine reproductive and respiratory syndrome virus using a duplex real-time RT-PCR 显示文摘 | Cheng D Zhao J J Li N | 2008 | J Virol Methods2008，151，2： | 1 |
| 5 | A study on technique to estimate impact location of loose part using Wigner-Ville distribution显示文摘 | KIM Y B KIM S J CHENG H D | 2003 | Progress in Nuclear Energy2003，43，： | 1 |
| 6 | Threshold selection based on fuzzy c partition entropy approach 显示文摘 | Cheng H D Chen J R Li Jiguang | 1998 | Attem Recognition1998，31，7： | 1 |
| 7 | Three- dimensional modeling and application in geological exploration engineering显示文摘 | GONG J Y CHENG P G WANG Y D | 2004 | Computers & Geosciences2004，30，4： | 1 |
| 8 | Emergence of excitotoxicity in cultured forebrain neurons coincides with larger glutamate-stimulated i increases and NMDA receptor mRNA levels显示文摘 | CHENG C FASS D M REYNOLDS I J | 1999 | Brain Res1999，849，12： | 1 |
| 9 | Three-dimensional modeling and application in geological exploration engineering显示文摘 | Gong J Y Cheng P G Wang Y D | 2004 | Computers and Geosciences2004，30，4： | 1 |
| 10 | On quadratic Lyapunov functions显示文摘 | CHENG D GUO L HUANG J | 2003 | IEEE Trans on Automatic Control2003，48，5： | 1 |
| 11 | Threshold selection based on fuzzy c _ partition entropy approach显示文摘 | Cheng H D Chen J R Li Jiguang | 1998 | Pattern Recognition1998，31，7： | 1 |
| 12 | Common due- window assignment and scheduling of linear time- dependent deteriorating jobs and a deteriorating maintenance activity 显示文摘 | Cheng T C E Yang S J Yang D L | 2012 | International Journal of Production Economics2012，135，1： | 1 |
| 13 | Osthole stimulates osteoblast differentiation and bone formation by activation of beta-catenin-BMP signaling显示文摘 | Tang DZ Hou W Zhou Q Zhang M Holz J Sheu TJ Li TF Cheng SD Shi Q Harris SE Chen D Wang YJ | 2010 | J Bone Miner Res2010，25，6： | 1 |
| 14 | High-level extracellular production of α-cyclodextrin glycosyltransferase with recombinant Escherichia coli BL21 (DE3)显示文摘 | Cheng J Wu D Chen S | 2011 | Journal of Agricultural and Food Chemistry2011，59，8： | 1 |
| 15 | Automated segmentation of ultrasonic breast lesions using statistical texture classifica- tion and active contour based on probability distance 显示文摘 | LIU B CHENG H D HUANG J | 2009 | Ultrasound Med Biol2009，35，： | 1 |
| 16 | Preparation and properties of nano-silica modified nega- tive acrylate photoresist 显示文摘 | Lee C K Don T M Lai W C Chert C C Lin D J Cheng L P | 2008 | Thin Solid Films2008，516，23： | 1 |
| 17 | Characterization of a virion occlusion-defective Autographa californica multiple nucleopolyhedrovirus mutant lacking the p26,p10and p74genes显示文摘 | Wang L Salem T Z Campbell D J Turney C M Kumar C M Cheng X W | 2009 | J Gen Virol2009，90，7： | 1 |
| 18 | Evaluation of a multiplex real-time RT-PCR for quantitative and differential detection of wild-type viruses and C-strain vaccine of Classical swine fever virus 显示文摘 | ZHAO J J CHENG D LI N | 2008 | Vet Microbiol2008，126，13： | 1 |
| 19 | Swim-bed technology as an innovative attached-growth process for, high- rate wastewater treatment显示文摘 | Rouse J D Yazaki D Cheng Y | 2004 | Japanese Journal of Water Treatment Biology2004，40，3： | 1 |
| 20 | Mieroealcifieation detection using fuzzy logic and scale space approaches显示文摘 | CHENG H D WANG J L SHI X J | 2004 | Pattern Recognition2004，37，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员