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| 1 | Modeling cardiac arrest and resuscitation in the domestic pig显示文摘Cardiac arrest remains a leading cause of death and permanent disability worldwide. Although many victims are initially resuscitated, they often succumb to the extensive ischemia-reperfusion injury inflicted on the internal organs, especially the brain. Cardiac arrest initiates a complex cellular injury cascade encompassing reactive oxygen and nitrogen species, Ca2+ overload, ATP depletion, pro- and anti-apoptotic proteins, mitochondrial dysfunction, and neuronal glutamate excitotoxity, which injures and kills cells, compromises function of internal organs and ignites a destructive systemic inflammatory response. The sheer complexity and scope of this cascade challenges the development of experimental models of and effective treatments for cardiac arrest. Many experimental animal preparations have been developed to decipher the mechanisms of damage to vital internal organs following cardiac arrest and cardiopulmonary resuscitation(CPR), and to develop treatments to interrupt the lethal injury cascades. Porcine models of cardiac arrest and resuscitation offer several important advantages over other species, and outcomes in this large animal are readily translated to the clinical setting. This review summarizes porcine cardiac arrest-CPR models reported in the literature, describes clinically relevant phenomena observed during cardiac arrest and resuscitation in pigs, and discusses numerous methodological considerations in modeling cardiac arrest/CPR. Collectively, published reports show the domestic pig to be a suitable large animal model of cardiac arrest which is responsive to CPR, defibrillatory countershocks and medications, and yields extensive information to foster advances in clinical treatment of cardiac arrest. | Brandon H Cherry Anh Q Nguyen Roger A Hollrah Albert H Olivencia-Yurvati Robert T Mallet | 2015 | World Journal of Critical Care Medicine2015，4，1： | 2 |
| 2 | The one-dimensional cutting stock problem with usable leftover - A heuristic approach显示文摘 | CHERRI A C ARENALES M M YANASSE H H | 2009 | European Joumal of Operational Research2009，196，3： | 1 |
| 3 | Description of ultrasonic vocalizations of the mouse lemur(Microcebus murinus)and the fat-tailed dwarf lemur ( Cheirogaleus medius) 显示文摘 | CHERRY J A IZARD M K SIMONS E | 1987 | Am J Primatol1987，13，： | 1 |
| 4 | , Abnormally High Ammonium of Natural Origin in a Coastal Aquifer- Aquitard System in the Pearl River Delta, China 显示文摘 | Jiao J J Wang Y Cherry J A | 2010 | Environ Sei Technol :2010，44，19： | 1 |
| 5 | Pregabalin reduces pain and improves sleep and mooddisturbances in patients with post-herpetic neuralgia : resultsof a randomised,placebo-controlled clinical trial显示文摘 | SABATOWSKI R GALVEZ R CHERRY D A | 2004 | Pain2004，109，12： | 1 |
| 6 | Accumulation and cellular distribution of 241Am,210po and 210pb in two marine algae 显示文摘 | FISHER N S BURNS K A CHERRY R D | 1983 | Marine Ecology Progress Series1983，11，： | 1 |
| 7 | Trophoblasts expression Fas ligand: A proposed mechanism for immune privilege in placenta and maternal invasion显示文摘 | Uckan D Steele A Cherry | 1997 | Mol Hum Reprod1997，3，8： | 1 |
| 8 | Pregabalin re- duces pain and improves sleep and mood disturbances in patients with post-herpetic neuralgia: results of a randomised, placebo controlled clinical trial显示文摘 | SABATOWSKI R GDLVEZ R CHERRY D A | 2004 | Pain2004，109，： | 1 |
| 9 | The one-dimensional cutting stock prob- lem with usable leftover-A heuristic approach 显示文摘 | CHERRI A C | 2009 | Eu- ropean Journal of Operational Research2009，196，3： | 1 |
| 10 | CVD diamond:controlling structure and morphology显示文摘 | Ahmed W Rego C A Cherry R | 2000 | Vacuum2000，56，3： | 1 |
| 11 | On the long- term hydraulic gradient in the thick clayey aquitard in the Sarnia region, Ontario 显示文摘 | HUSA1N M M CHERRY J A FIDLER S FRAPE S K | 1998 | Canadian Geotechnical Journal1998，35，6： | 1 |
| 12 | MultiSlock Principal Component Analysis Based on a Combined Index for Semiconductor for Fault Detection and Identification 显示文摘 | G A Cherry S J Qin | 2006 | Semiconductor Manufacturing (S0894-6507)2006，19，2： | 1 |
| 13 | HIV-associated sensory neuropathies显示文摘 | Keswani SC PC Cherry CL Hoke A | 2002 | AIDS2002，816，16： | 1 |
| 14 | Groundwater contamination: Pump - and - treat remediation 显示文摘 | Mackay D M Cherry T A | 1989 | Environment Science and Technology1989，23，6： | 1 |
| 15 | Attenuation of nitrate in aquitard sediments of southern Ontario显示文摘 | Robertson W D Russell B M Cherry J A | 1996 | Journal of Hydrology1996，180，： | 1 |
| 16 | Interruptive light restricted feeding of broiler chickens显示文摘 | Beane W L Cherry J A | 1979 | Poultry Science1979，58，： | 1 |
| 17 | Supplemental ascorbic acid and heat stress in broiler chicks显示文摘 | Cherry J A | 1984 | Poult Sci1984，，： | 1 |
| 18 | Temporary floating island formation maintains wetland plant species richness: The role of the seed bank显示文摘 | Cherry J A Gough L | 2006 | Aquatic Botany2006，85，： | 1 |
| 19 | Elevated CO2enhances biological contributions to elevation change in coastal wetlands by offsetting stressors associated with sea-level rise显示文摘 | CHERRY J A MEKEE K L GRACE J B | 2009 | Journal of Ecology2009，97，： | 1 |
| 20 | Stable Isotopes of Oxygen and Nitrogen in Source Identification of Nitrate from Septic Systems显示文摘 | Aravena R Evans M L Cherry J A | 1993 | Ground Water1993，31，2： | 1 |
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