|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Uptake and mitochondrial dysfunction of alpha-synuclein in human astrocytes, cortical neurons and fibroblasts显示文摘The accumulation and aggregation of alpha-synuclein(α-syn)in several tissue including the brain is a major pathological hallmark in Parkinson’s disease(PD).In this study,we show that α-syn can be taken up by primary human cortical neurons,astrocytes and skin-derived fibroblasts in vitro.Our findings that brain and peripheral cells exposed to α-syn can lead to impaired mitochondrial function,leading to cellular degeneration and cell death,provides additional evidence for the involvement of mitochondrial dysfunction as a mechanism of toxicity of α-syn in human cells. | Nady Braidy Wei-Ping Gai Ying Hua Xu Perminder Sachdev Gilles J Guillemin Xing-Mai Jiang J William O Ballard Martin P Horan Zhi Ming Fang Beng H Chong Daniel Kam Yin Chan | 2013 | Translational Neurodegeneration2013，2，1： | 4 |
| 2 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 3 | A multiple-Doppler synthesis and continuity adjustment technique (MUSCAT) to recover wind components from Doppler radar measurements 显示文摘 | Bousquet O Chong M | 1998 | J Atmos Oceanic Tech1998，15，2： | 1 |
| 4 | Diversity among commu-nity isolates of methicillin-resistant Staphylococcus aureus in Australia显示文摘 | O'Brien FG Lim TT Chong FN | 2004 | J Clin Microbiol2004，42，7： | 1 |
| 5 | A review of microv- alves显示文摘 | KWANG W O CHONG H A | 2006 | Journal of Micromechanics and Micro- engineering2006，16，： | 1 |
| 6 | Renal dysfunction,as measured by the modification of diet in renal disease equations,and outcome in patients with advanced heart failure显示文摘 | GARDNERL R S CHONG K S O'MEARA E | 2007 | Eur Heart J2007，28，24： | 1 |
| 7 | Minia- turization of pinch type valves and pumps for practi- cal micro total analysis system integration 显示文摘 | KWANG W O RONG R CHONG H A | 2005 | Journal of Micromechanics and Microengineering2005，15，： | 1 |
| 8 | ERK1/2 activation mediates Abeta oligomer-induced neurotoxicity via caspase-3 activation and tau cleavage in rat organotypic hippocampal slice cultures显示文摘 | Chong Y H Shin Y J Lee E O | 2006 | J Biol Chem2006，281，20： | 1 |
| 9 | Poor outcomes for IgD multiple myeloma patients following high-dose melphalan and autologous stem cell transplantation:a single center experience显示文摘 | CHONG Y P KIM S KO O B | 2008 | J Korean Med Sci2008，23，5： | 1 |
| 10 | 显示文摘 | Leung A C W Chong J H Patrick B O | 2003 | Macromolecules2003，36，14： | 1 |
| 11 | An improved conjugate gradient scheme to the solution of least squares SVM显示文摘 | Wei C Chong J O Keerthi S | 2004 | IEEE Transactions on Neural Networks2004，1，11： | 1 |
| 12 | Simple Computational Methods of the AP Algorithm for Maximum Likelihood Localization of Multiple Radiating Sources 显示文摘 | SEONG K O CHONG K U | 1992 | IEEE Transactions on Signal Processing1992，40，11： | 1 |
| 13 | Combined Drying of Apple Cubes by Using of Heat Pump, Vacuum-Microwave, and Intermittent Techniques显示文摘 | Chien Hwa Chong Adam Figiel Chung Lim Law Aneta Wojdy?o | 2014 | Food and Bioprocess Technology2014，，4： | 1 |
| 14 | A review of microvalves显示文摘 | KWANG W O CHONG H A | 2006 | Journal of Micromechanics and Microenginering2006，16，5： | 1 |
| 15 | Epidemiology, clinical charac- teristics and antimierobial resistance patterns of community -ac- qired pneumonia in 1702 hospitalized children in Singapore显示文摘 | Chiang W Teoh O Chong C | 2007 | Re- spirology2007，12，2： | 1 |
| 16 | Stepping-Ran- dom Code: a Rateless Erasure Code for Short-Ingth Messa- ges显示文摘 | Chong Z K Bok-Min G O I Ohsaki H | 2013 | IEICE Transactions on Communications2013，96，7： | 1 |
| 17 | Effect of enzymatic transesterification on the melting points of palm stearin-sun- flower oil mixtures显示文摘 | Lai O Ghazali H Chong C | 1998 | J Am Oil Chem Soc1998，75，： | 1 |
| 18 | Epidemiology,clinical characteristics and antimicrobial resistance patterns of community acquired pneumonia in 1702 hospitalized children in Singapore显示文摘 | Chiang W C Teoh O H Chong C Y | 2007 | Respirology2007，12，2： | 1 |
| 19 | Numerical study of water mitigation effects on blast wave 显示文摘 | Cheng M Hung K C Chong O Y | 2005 | Shock Waves2005，14，3： | 1 |
| 20 | Locatization of stem rust resistance genes and associated molecular marker in cultivated oat 显示文摘 | DONOUGHUE O CHONG J WIGHT C P | 1996 | Phytopathology1996，86，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员