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119篇 您的检索式：作者名="Chris Y"

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	题名	作者	年代	出处	被引量
1	On tolerability and safety of a maintenance treatment with 6-thioguanine in azathioprineor 6-mercaptopurine intolerant IBD patients显示文摘AIM: To determine the tolerability and safety profile of a low-dose maintenance therapy with 6-TG in azathioprine (AZA) or 6-mercaptopurine (6-MP) intolerant inflammatory bowel disease (IBD) patients over a treatment period of at least 1 year.METHODS: Database analysis.RESULTS: Twenty out of ninety-five (21%) patients discontinued 6-TG (mean dose 24.6 mg; mean 6-TGN level 540 pmol/8×108 RBC) within 1 year. Reasons for discontinuation were GI complaints (31%), malaise (15%)and hepatotoxicity (15%). Hematological events occurred in three patients, one discontinued treatment. In the 6-TG-tolerant group, 9% (7/75) could be classified as hepatotoxicity. An abdominal ultrasound was performed in 54% of patients, one patient had splenomegaly.CONCLUSION: The majority of AZA or 6-MP-intolerant IBD patients (79%) is able to tolerate maintenance treatment with 6-TG (dosages between 0.3 and 0.4 mg/kg per d). 6-TG may still be considered as an escape maintenance immunosuppressant in this difficult to treat group of patients, taking into account potential toxicity and efficacy of other alternatives. The recently reported hepatotoxicity is worrisome and 6-TG should therefore be administered only in prospective trials.	Nanne KH de Boer Luc JJ Derijks Lennard PL Gilissen Daniel W Hommes Leopold GJB Engels Sybrand Y de Boer Gijsbertus den Hartog Piet M Hooymans Anja BU M(?)kelburg Barend D Westerveld Anton HJ Naber Chris JJ Mulder Dirk J de Jong	2005	World Journal of Gastroenterology2005，11，35：	4
2	Overriding imatinib resistance with a novel Abl kinase inhibitor显示文摘	Neil P Shah Chris Tran Francis Y Lee	2004	Science2004，305，：	1
3	Game theoretical multi-agent modelling of coalition formation for multilateral trades显示文摘	Yeung Chris S K Poon Ada S Y	1999	IEEE Trans on Power Systems1999，14，3：	1
4	Establishment of a database of emission factors for atmospheric pollutants from Chinese coal-fired power plants显示文摘	Zhao Y Wang S X Chris P Nielsen	2010	Atmospheric Environment2010，44，12：	1
5	A genetic and cytogenetic map for the Duck (Anas platyrhynchos)显示文摘	Huang Y Zhao Y Chris S H	2006	Genetics2006，173，：	1
6	Family-Supportive Work Envi- ronment and Employee Work Behaviors: An Investigation of Mediating Mechanisms显示文摘	Aryee S Chris W L C Kim T Y	2013	Journal of Management2013，39，3：	1
7	Specific expression of cytochrome P4501A1 gene in gill, intestine and liver of tilapia exposed to coastal sediments 显示文摘	Chris K C Yeung H Y Woo P S	2001	Aquatic Toxicology2001，54，：	1
8	Suppression subtractive hybridization: a method for generating differentially regulated or tissue-specific cDNA probes and libraries显示文摘	DIATCHENLO L CHRIS L Y F CAMPBELL A P	1996	Proc Natl Acad Sci USA1996，93，：	1
9	Ilearn self-learning defect classifier显示文摘	CHRIS A C THEODORE Y F CHARLES F	1998	Iron and Steel Engineer1998，75，8：	1
10	Ultrafast and direct imprint of nanostructures in silicon显示文摘	Chou S Y Keimel Chris Gu Jian		0，，20：	1
11	Ultrafast and direct imprint of nanostructures in silicon显示文摘	Stephen Y C Chris K Jian G	2002	Nature2002，417，20：	1
12	A study on the effects of high pressure and heat on Bacillus subtilis spores at low pH显示文摘	ELKE Y CHRIS W	2001	Int J of Food Microbiol2001，64，：	1
13	Experimental Investigation on CBN Turning of Hardened AISI 52100 Steel显示文摘	Chou Y K Chris J E Barash M M	2002	Journal of Materials Processing Technology2002，，124：	1
14	Data mining techniques for customer relationship management显示文摘	Chris R Jyun-Cheng W David C Y	2002	Technology in Society2002，24，4：	1
15	Holistic views of knowledge management models显示文摘	BAIYIN Y WEI Z CHRIS V	2009	Advances in Developing Human Resources2009，11，3：	1
16	Kirk, Behavior of Metal under the Conditions of Roasting MSW Incinerator Fly Ash with Chlorinating Agents显示文摘	Chris C Y Chart Donald W	1999	Journal of Hazardous Materials1999，，64：	1
17	The structure, functions and evolution of Su (Ste) repeats on the Y chromosome of drosophila melanogaster显示文摘	TU Z M HE G Y CHRIS GILLTES	2005	Journal of Entomology2005，2，1：	1
18	Isogo00 and sup- ply chain efficiency: Empirical evidence on inventory and account receivable days 显示文摘	Chris K Y Yeung A C Cheng T E	2009	International Journal of Production Economics2009，118，2：	1
19	State of charge estimation of lithium-ion batteries in electric drive vehicles using extended Kalman Filtering显示文摘	CHEN Z FU Y H CHRIS M C	2013	IEEE Transactions on Vehicular Technology2013，62，3：	1
20	The behaviour of al in MSW incinerator fly ash during thermal treatment显示文摘	Chris C Y Chan D W K Hilary M	2000	Journal of Hazardous Materials2000，76，1：	1

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